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Query: UMLS:C0015672 (fatigue)
 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Tiredness may be caused by the brain injury due to the tumor or the treatment in patients with glioblastoma multiforme (GBM). Some patients describe a sense of tiredness particularly after radiation or oral chemotherapy. To evaluate tiredness level of patients with GBM during preoperative, postoperative and radiotherapy we here eamined a sample of 38 patients. Data were collected over six months in a neurosurgery clinic. Patients assigned to Group I were given a booklet and information about radiotherapy, oral temozolomide and tiredness. Group II received only the booklet. The chi-squared test were used to determine differences in tiredness between Group I and Group II, with Spearman's correlation for post-radiotherapy results (3 and 6 months postoperative). In conclusion, the level of tiredness was assessed to be significantly better in Group I than in Group II. Levels of tiredness in patients with GBM were greatly affected by the radiotherapy and oral chemotherapy (temozolomide).
Asian Pac J Cancer Prev
PMID:Radiotherapy-related tiredness in patients with glioblastoma multiforme (GBM). 1899 27

This study was conducted to examine the feelings, symptom management, and needs of patients with gynecological cancer receiving chemotherapy at Chiang Mai University Hospital, Chiang Mai, Thailand. During the period July 2006 and June 2007, 286 patients were recruited. The most common chemotherapeutic regimen was paclitaxel and carboplatin followed by single carboplatin and weekly cisplatin. Five severe and frequent complications were as follows: alopecia, anorexia, fatigue, nausea, and vomiting. Some 41.9% could well tolerate with such complications but 50.3% had various feelings including irritability, boredom, dejection, fear, stress, and anxiety. Anorexia was the symptom that the majority of them could best manage, 17.4% by eating as much as they can and 32.6% by selecting different foods from normal, such as fruit, sweetmeats, noodles, milk. For nausea and vomiting, 31.3% managed by eating fruit, drinking sour juice, and holding sour fruit in mouth, and 16.0% used the breathing method, eating something cold, such as ice-cream, or hot food like noodles. For health needs, 41.0% needed encouragement, care, health education, and information from doctors and nurses, and 5.0% needed care and encouragement from their family, and sympathy from neighbors and colleagues. In conclusion, gynecological cancer patients receiving chemotherapy experience a variety of feelings, symptom management. and health needs. Nurses need to explain the pathology of the occurring symptoms so that the patients can understand and accept the symptoms to lessen their negative impact.
Asian Pac J Cancer Prev
PMID:Symptom management in patients with cancer of the female reproductive system receiving chemotherapy. 1925 70

The incidence and mortality of cancer are increasing day to day. Advanced cancer is cancer that has grown beyond the organ where it first started. Often it has spread widely throughout the body. In advanced cancer when cure is impossible, symptoms should be the focus of attention. Having advanced cancer can bring anxiety and uncertainty to life of patients. Most people who have survived cancer and completed their treatment will say that they live with the underlying fear that their cancer will return. Some people with advanced cancer are living longer and with better quality of life (QOL). Each person with advanced cancer has unique experience. Advanced cancer is not the same for everyone; it behaves differently depending on what patients' primary cancer diagnosis have been. Symptoms then get worse and treatments are needed to help them to control. These symptoms can often be treated. Likewise, each person faced with recurrent cancer will cope differently too. Assessing and understanding the impact of cancer on patients is, therefore, very important for providing the appropriate care and for improving patients' QOL. Understanding the reasons why some individuals become depressed and faced with some problems in advanced cancer has become an increasingly important area in palliative care. By interest in end of life care, clinicans, nurses, social workers, psychologists, and researchers alike have begun to focus their attention on identifying factors that might facilitate coping with advanced cancer. The goals of this study was to examine cancer related stressors and how patients coping with them. For understanding cancer related stressors and coping patterns of patients with advanced cancer current literature has been examined. In this study the specific symptoms and concerns which are faced by advanced cancer patients has been assigned shortly on a priori basis in to the dimensions of physicial symptomps, psychological symptoms, social concerns and, existential issues. Coping with this stressors some useful coping strategies (problem focused and emotional focused approach) are suggested in this study. Framework which is developed by this study can be useful for understanding cancer related stressors, some interventions to assist cancer patients to manage symptoms (pain, fatigue) and coping strategies for health care staff who worked with advanced cancer patients. Health care staff who are aware of the common stressors in advanced cancer, palliative care and end of life care may identify more readily the need for support and assistance with coping strategies, thus improving the overall QOL of their patients. Providing psychological and social support requires interdisciplinary collaboration guided by a perspective of QOL in palliative care.
Asian Pac J Cancer Prev 2010
PMID:Coping with stress in patients with advanced cancer. 2059 Mar 56

The epidemiology of depression showed that the rates are high. For example, the World Mental Health Survey, an epidemiologic community study conducted in 28 countries, found a life-time prevalence rate that ranged from 3.3 % in Nigeria to 21.4% % in the US. With regard to persons with cancer, 12.5% of a sample of over 17,000 respondents over the age of 50 of a US survey of community-dwelling adults found that people that reported they had cancer had higher risk of fatigue (OR =1.5 95% CI 1.3-1.6); depression (OR=1.2, 95% CI 1.1-1.4) and pain (OR =1.2, 95% CI 1.03-1.3.).The rate of depression seems to be differently associated with cancer site. For example: It is higher in pancreatic cancer (33%-50%) and lung (11%-44%), and it is lower in lymphoma (8%-19%) and colon (13% and 25%). For breast cancer--likely the most studied cancer site- the prevalence ranges from 1.5% to 46%. Ciaramelli and Poli (2001) found that depressed persons had more pain and metastasis than the non-depressed but no more lifetime depression that the non-depressed. In terminally patients, studies have found that the higher the level of disability the higher the rates of depression. Interestingly, while almost all studies of depression in the community found higher rates in women than in men--this is far from the rule among persons with cancer. Despite the marked burden and the existence of effective treatment, a very large proportion of the persons with depression remain untreated. The causes to be imputed for the treatment gap are of different nature. Some of these causes are related to the suffering person, to the social context and to the health system. Often, the treating physicians fail to identify depression and to treat it properly. For example, in one evaluation of 456 outpatients with solid tumors a minority (14%) of the depressed were identified as such. Why is it important to assess depression in persons with cancer? Untreated depression both enhances the risks to life and it lowers the quality of life. It may be associated to a reduced chance of survival in women with early stage breast cancer. One possible reason is limited adherence to the treatment plan. Timely identification and well prescribed and conducted tre.
Asian Pac J Cancer Prev 2010
PMID:The treatment gap of depression in persons with cancer. 2059 Mar 62

The aim of this descriptive, cross-sectional study was to determine information requirements of patients with typical meningiomas after surgery. The study sample consisted of 20 patients who underwent surgery for brain tumours in neurosurgery clinics of a university hospital. Permission to conduct research was obtained from all patients and from the hospital. Before the surgery, a booklet was given to patients for training. Patients were followed up one, three, six and 12 months later by the phone after the surgery and asked to report their problems. All questions were recorded and answered. Data were collected by the socio-demographic, patient symptom and health status questionnaire. Descriptive data were analyzed using percentage and arithmetic averages. Comparative statistics were evaluated using chi-square. Patients wanted information about diet, physical therapy and rehabilitation, quick thinking difficulties, fasting, headache, irritability, personality change, fatigue, driving, deep vein thrombosis during the follow up. There was a significant difference between their health status and fear of seizures and recurrent tumor, forgetfulness, lack of concentration (p < 0.05). Although they received health education and booklet, patients needed more information during the 12 months after surgery. Therefore it suggested that monitoring the patient's needs is necessary.
Asian Pac J Cancer Prev 2011
PMID:Information needs of patients with meningiomas. 2154 9

Breast and cervical cancers impose large costs on society. Performing breast and cervical cancer screening tests (BCCST), considered as a health promotion behavior, is therefore important. This qualitative study based on the "integrated model of planned behavior and self-efficacy (PBSEIM)" was conducted to assess influencing factors. A total of seventy female workers aged between 20-45 years from Tehran suburban factories were recruited by purposeful sampling to participate in ten focus group discussions. Data were analyzed using the conventional content analysis method. The majority had an appropriate attitude toward BCCST, stressing the importance of family' s especially husband' s encouragement as the subjective norm. Low knowledge, depression, fatigue, shyness and fear of examination and diagnosis of cancer, poor quality of services and financial barriers were mentioned as effective negative factors. The majority reported low self efficacy for planning to perform the behavior and had no intention to undergo screening in the next three months. So interventions are necessary to overcome effective barriers and improve women's health.
Asian Pac J Cancer Prev 2011
PMID:Factors for performing breast and cervix cancer screening by Iranian female workers: a qualitative-model study. 2212 91

Allergic rhinitis is a disease with an increasing prevalence throughout the world that severely affects the quality of life of individuals suffering from it. Nasal congestion is the most common and bothersome symptom, and is often associated with sleep-disordered breathing, which is thought to be the reason for sleep impairment in individuals with rhinitis. The end result is a decrease in quality of life and productivity and an increase in daytime sleepiness. Treatment with intranasal corticosteroids has been shown to reduce nasal congestion. Data on sleep-related end points from clinical trials of intranasal corticosteroids indicate that this reduction is associated with improved sleep, reduced daytime fatigue, and improved quality of life. Other therapies, such as montelukast, also have a positive influence on congestion and sleep. This review examines nasal congestion and the associated sleep impairment of allergic rhinitis patients. It explores the adverse effects of disturbed sleep on quality of life and how these conditions can be reduced by therapies that decrease congestion.
Asian Pac J Allergy Immunol 2011 Dec
PMID:Congestion and sleep impairment in allergic rhinitis. 2229 8

Quality of life (QOL) was assessed in 141 filarial lymphedema patients and 128 healthy people in the Colombo district, Sri Lanka, by administering modified, translated, and validated (in Sri Lanka) versions of the Short Form 36 health survey questionnaire (SF-36) and the 30-item General Health questionnaire (GHQ-30). The GHQ-30 assesses the current mental health status. The SF-36 measures health on 8 multi-item dimensions covering functional state, well-being, and overall evaluation of health (physical functioning, role limitations resulting from physical health problems, role limitations resulting from emotional problems, energy/fatigue, emotional well-being, social functioning, pain and general health). By SF-36, patients experienced poorer physical functioning, more role limitations resulting from physical health conditions, less emotional well-being, poorer social functioning, and more pain than healthy individuals. By GHQ-30, mental well-being of healthy controls was significantly better than that of patients. The significant difference in the QOL as perceived by filarial lymphedema patients and healthy individuals reiterates the importance of morbidity control in patients affected by this disease.
Asia Pac J Public Health 2015 Mar
PMID:Physical, psychological, and social aspects of quality of life in filarial lymphedema patients in Colombo, Sri Lanka. 2230 36

Sunitinib is the gold standard of care for patients with metastatic renal cell carcinoma, demonstrating an overall survival benefit of over 2 years in a pivotal phase 3 trial of 750 patients. While sunitinib is generally well tolerated with most adverse events, manifesting as mild to moderate in severity and manageability, it has a distinctive adverse event profile that benefits from careful monitoring during treatment. As sunitinib gains widespread use across the globe, best practices are being developed for specific patient groups. This review will focus on the current clinical trial data in Asian populations and on the mechanism, incidence and management of selected sunitinib-related adverse events, including hand-foot syndrome, hypertension, proteinuria, cardiac toxicities, myelosupression, fatigue/asthenia, hypothyroidism, diarrhea and hepatotoxicity. Taken together, the developing body of literature reviewed here demonstrates that sunitinib is well tolerated in Asian patients and provides efficacy that is similar, if not superior, to other patient groups. Asian patients, like all patients, should begin treatment of sunitinib at 50 mg on Schedule 4/2 (4 weeks on treatment/2 weeks off). Prophylactic measures, good communication between patient and health-care providers, and early, aggressive intervention at the development of adverse events can limit the dose reductions required and maximize both patients' response to treatment and their quality of life.
Asia Pac J Clin Oncol 2012 Jun
PMID:Management of sunitinib adverse events in renal cell carcinoma patients: the Asian experience. 2252 72

Allergic rhinitis (AR) is the most common chronic pediatric disorder. The International Study for Asthma and Allergies in Childhood phase III found that the global average of current rhinoconjunctivitis symptoms in the 13-14 year age-group was 14.6% and the average prevalence of rhinoconjunctivitis symptoms in the 6-7 year age-group was 8.5%. In addition to classical symptoms, AR is associated with a multidimensional impact on the health related quality of life in children. AR affects the quality of sleep in children and frequently leads to day-time fatigue as well as sleepiness. It is also thought to be a risk factor for sleep disordered breathing. AR results in increased school absenteeism and distraction during class hours. These children are often embarrassed in school and have decreased social interaction which significantly hampers the process of learning and school performance. All these aspects upset the family too. Multiple co-morbidities like sinusitis, asthma, conjunctivitis, eczema, eustachian tube dysfunction and otitis media are generally associated with AR. These mostly remain undiagnosed and untreated adding to the morbidity. To compound the problems, medications have bothersome side effects which cause the children to resist therapy. Children customarily do not complain while parents and health care professionals, more often than not, fail to accord the attention that this not so trivial disease deserves. AR, especially in developing countries, continues to remain a neglected disorder.
Asia Pac Allergy 2012 Apr
PMID:Impact of allergic rhinitis in school going children. 2270 58


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