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Query: UMLS:C0015672 (fatigue)
 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Investigated auditory word discrimination skill in children diagnosed as having minimal brain dysfunction (MBD), a heretofore unexplored topic in the study of MBD. A lack of auditory discrimination skill seems relevant to learning deficiency in language acquisition, a typical sign of MBD. The present study tested the hypothesis that phonemic aural discriminations would be difficult to make for boys diagnosed as having MBD. Errors and nonresponses made while Ss performed an extended auditory word discrimination task were compared between a group of 26 boys diagnosed as having MBD and a matched normal group. As expected, the MBD group had a significantly higher error rate than the normal group even when Ss were discriminating easy word pairs composed of dissimilar items (e.g., reading, math). These and other results suggested that the MBD group was very susceptible to fatigue even while motivated to perform well and while able to improve with practice. The relatively inferior performance of the MBD group was interpreted as resulting directly from a lack of auditory discrimination skill and indirectly from fatigue and its accompanying attention loss.
J Clin Psychol 1977 Oct
PMID:Auditory word discrimination in male children diagnosed as having minimal brain dysfunction. 2 90

The work output and the mental and physical fatigue generated by a dental procedure is affected by the length and type of operation, physical facilities, the amount of cooperation given by the patient, operating techniques, and the effective teamwork and rapport of the operatory dental team. Fatigue is also generated by stresses that arise outside of the office and which, when superimposed over the normal operating stresses of the office, can have a cumulative effect of decreasing output and increasing mental and physical fatigue for the dentist, the assistant, and the patient. Probably the three most important means to compensate for both routine and nonroutine physical and mental stresses of any type or origin are: (1) learn to cope with or resolve the origin of the stress; (2) develop a pattern of healthy living; (3) cultivate job satisfaction.
Dent Clin North Am 1978 Jul
PMID:Ergonomics. Reducing mental and physical fatigue in the dental operatory. 2 55

1 We have studied the effects of single oral doses of 80 mg propranolol and 100 mg metoprolol on the cardiovascular and respiratory responses to progressive exercise in nine healthy men in double-blind, placebo-controlled experiment. As judged by their effects on exercise heart rate and cardiac output the doses of the two drugs used were equivalent. 2 Beta-adrenoceptor blockade reduced oxygen consumption by 3.5% over the whole work range with an increase in the respiratory exchange ratio of 0.056 units. Carbon dioxide production and exercise ventilation were unchanged. The two drugs had similar effects. Possible mechanisms for these observations are discussed. 3 Perceived exertion during exercise was increased by both the beta-adrenoceptor blocking drugs and this may be of relevance to the symptom of fatigue reported by patients on these drugs. Endurance, assessed as either total work done or maximal work achieved, was reduced by 15%.
Br J Clin Pharmacol 1979 Aug
PMID:The effect of beta-adrenoceptor blockade on factors affecting exercise tolerance in normal man. 3 85

The effect standardized exercise had upon sleep was studied with eight subjects. A pilot study assessed individual work capacity by the sub-maximal estimation of VO2 max. In the main study each subject performed the exercise, once a.m. and once p. m., on different days. Sleep was scored into stages and an additional sub-division of stage 2 containing 10-20% by time of delta. Comparison with baseline showed no significant whole night changes with any criteria following either a.m. or p. m. exercise. After p.m. exercise there was a significant increase in stage 3 for the first half of the night. It was concluded that ensuing wakefulness following early daytime exercise is sufficient for recovery, but late daytime exercise may result in an intrusion of recovery into initial sleep. Sleep is not seen to be necessary for recovery from muscular fatigue.
Electroencephalogr Clin Neurophysiol 1976 Feb
PMID:Time of day effects with standardized exercise upon subsequent sleep. 5 58

The EEG was recorded in 27 subjects during hangover. Male healthy volunteers drank 1.75 g/kg body weight of ethanol in 3 h and the EEG was recorded 14-16 h later when the degree of hangover was highest. For control purposes a second EEG was recorded after a similar session when subjects drank water instead of ethanol. A third record was taken in normal laboratory conditions. T5-A1 and O1-A1 derivations were subjected to computer analysis from which spectral and frequency parameters were calculated. Visual analysis of the EEG during hangover showed a decrease and slowing of alpha activity and an increase in theta activity. Spectral analysis of the EEG gave a statistically significant increase in 7-8 c/sec activity during hangover. The EEG change could not be explained in terms of blood alcohol level, hypoglycaemia or acidosis. Also fatigue could be excluded as a cause of EEG change by means of "water controls". The conclusion is that the slowing of the EEG during hangover is caused by the depressant action of ethanol, or its metabolites, on cortical function.
Electroencephalogr Clin Neurophysiol 1976 May
PMID:Electroencephalographic changes during experimental hangover. 5 42

The immunoglobulin class and subclass of cytophilic antibodies have been studied using peripheral leucocytes from twenty-two patients with allergic bronchopulmonary aspergillosis, aspergilloma and cryptogenic pulmonary eosinophilia. In patients with allergic bronchopulmonary aspergillosis, significantly increased histamine liberation occurred following challenge of their leucocytes with antisera to IgE, IgG2, IgG3 and IgG4 as well as with Aspergillus fumigatus antigen. The results were considerably modified if the patient was receiving corticosteroids at the time of the test. The presence of IgG2-specific antibody to A. fumigatus in the serum of one patient, capable of sensitizing donor leucocytes, was demonstrated in passive sensitization experiments. In two patients with uncomplicated aspergillomas no evidence of cytophilic antibody to any class was found although large amounts of precipitating IgG antibody was present in the serum. Two patients with aspergilloma and systemic symptoms of weight loss and fatigue (which have been interpreted by others as 'hypersensitivity' responses) had increased amounts of cytophilic antibody similar to those with allergic bronchopulmonary aspergillosis. Six patients with cryptogenic pulmonary eosinophilia were also studied. No evidence of specific antibody to A. fumigatus was found but, as a group, significantly increased histamine liberation using antisera to IgG2 was demonstrated. Individual patients also showed evidence of other classes of cytophilic antibody, one having IgE, three IgG3 and two IgG4. The relationship between heat-stable short-term sensitizing antibody (IgG STS) inducing immediate skin responses and the pattern of cytophilic antibodies found in our patients with bronchopulmonary aspergillosis having dual (immediate and late reactions) is discussed. Clinically these tests are of diagnostic value and they may be helpful in assessing symptomatic patients with aspergillomas for corticosteroid treatment.
Clin Exp Immunol 1976 Oct
PMID:Cytophilic antibodies in bronchopulmonary aspergilloma and cryptogenic pulmonary eosinophilia. 6 46

Neuromuscular adaptations to a submaximal static contraction for a period of 2 min were investigated using children as subjects to detect changes in the contributing frequency components of the electromyogram (EMG) recorded from surface electrodes. The purpose of this study was to determine the similarity between EMG response patterns of children and published data for adult subjects under similar conditions. Spectral analysis of the EMG signal revealed a shift to lower frequency components and a concurrent increase in total variance of the signal as a response to fatigue. The frequency shift and increase amplitude for the EMG signal were discussed in light of evidence for recruitment and synchronization of motor units and changes in muscle fiber conduction velocity as possible mechanisms.
Electroencephalogr Clin Neurophysiol 1978 Aug
PMID:Myoelectric frequency changes in children during static force production. 7 27

The professional ballet dancer presents all of the problems of any vigorous athlete. The problems include osteochondral fractures, fatigue fractures, sprains, chronic ligamentous instability of the knee, meniscal tears, impingement syndrome, degenerative arthritis of multiple joints and low back pain. Attention to minor problems with sound conservative therapy can avoid many major developments and lost hours. Observations included the extraordinary external rotation of at the hip without demonstrable alteration in the hip version angle and hypertrophy of the femur, tibia and particularly the second metatarsal (in female dancers). Careful evaluation of the range of motion of the extremities, serial roentgenographic examination, and systematic review of previous injuries, training programs and rehearsal techniques have been evaluated in a series of cases to provide the basis for advice to directors and teachers of the ballet.
Clin Orthop Relat Res 1975 Sep
PMID:A new consideration in athletic injuries. The classical ballet dancer. 12 36

The authors report 4 cases of pseudo-myasthenic syndrome followed with EMG for a period varying from a few months to 4 years. They go over the electrophysiological points which led to the diagnosis: small amplitude of the muscle potential evoked by simple shock and, in particular, the phenomenon of potentiation which may reach 2000 p. 100 during repetitive stimulation at high frequencies. Study of the behaviour of the muscle potential during ischaemia, which was carried out twice, showed an absence of fatigue of the potential which may be considered a sign of disturbance at the muscle level of the motor-end plate. On the other hand, EMG signs of peripheral neuropathy, which were found 3 times, rather suggests a motor neuropathy responsible for the presynaptic block. In 3 patients guanidine had a beneficial effect and no signs of paraneoplastic aetiology had occurred yet. The fourth case, with a bronchial neoplasm discovered at autopsy, was clearly improved by injectable lidocaine, for which no explanation can be supplied.
Rev Electroencephalogr Neurophysiol Clin
PMID:[Pseudo-myasthenic syndromes. Clinical and electromyographic review of 4 cases, one with an unusual reaction to lidocaine (author's transl)]. 20 77

The Compu-pet 100 diluter/dispenser is a versatile and accurate instrument which can be employed for a wide variety of microbiological tests and techniques. Time in performing tests is often more than halved when the diluter is used. Large numbers of tests can be performed with minimal fatigue.
J Clin Pathol 1975 Jan
PMID:The Compu-pet 100: a versatile dispenser-diluter for the mechanization of microbiological techniques. 23 70


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