Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0015672 (fatigue)
51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Agouron Pharmaceuticals is making their protease inhibitor, nelfinavir mesylate (Viracept), available in an expanded access program for people who are unable to use any of the three approved protease inhibitors due to intolerance, contraindication, or prior failure with those drugs. They must also have a CD4 count below 50. Viracept has already been studied in 500 patients, with the most frequent side effects being mild to moderate diarrhea, headache, and fatigue.
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PMID:New protease inhibitor available through expanded access. 1136 81