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 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

One potential complication of pedicle screw instrumentation is long-term nerve root irritation, most commonly resulting from medial or inferior screw malpositioning. This study evaluated the pullout strength and fatigue strength properties of a novel "rescue" revision screw designed to reduce the sequelae of medial screw malpositioning by eliminating threads along the section of the screw corresponding to the pedicular region. The results of this study revealed that a rescue screw with threads eliminated from one half of its circumference provided comparable pullout strength to fully threaded pedicle screws in cadaveric specimens. In addition, mechanical testing of the rescue screw did not show a decrease in fatigue strength characteristics compared with controls. These results suggest that the rescue screw may offer a way to decrease nerve root irritation caused by canal impingement without jeopardizing the overall strength of the spinal construct.
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PMID:Evaluation of the fixation and strength of a "rescue" revision pedicle screw. 1192 17

The authors of this article describe the surgical procedure for fixation of spondylolisthesis using transpedicular fixation, and offer a comparative evaluation of the DERO, CD, C-CD, SOCON, and STRYKER systems.<br /> The evaluation involved 36 patients operated in the Rehabilitation Clinic at the Lublin Academy of Medicine during the period 1994-2000. In 11 cases the DERO fixation system was used; in 5 cases, fixation with CD or C-CD instrumentation; in 15 cases, using the SOCON system; and in 5 cases with the STRYKER instrumentation.<br /> Indications for surgery included pain and symptoms of nerve root irritation with sciatic neuralgia. The concomitant neurological symptoms resulted from the displacement into the vertebral canal of fragments of the nucleus pulposus, or from bone-related stenosis of the vertebral canal and intervertebral foramina.<br /> Surgical treatment involved decompression of the nerve elements and internal fixation. In all the cases reported here posterior and postero-lateral spondylodesis was performed, while in 20 cases interbody spondylodesis was additionally performed, in 14 cases using interbody plugs.<br /> The authors analyze the reasons for complications, such implants working loose and fatigue fractures.
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PMID:Internal fixation systems in the surgical treatment of spondylolisthesis. 1803 23

In the fall of 2007, the Minnesota Department of Health was notified of 11 cases of an unexplained neurological illness, all linked to a pork processing plant, Quality Pork Processors, Inc., in Austin, MN. The cluster of workers had been experiencing similar symptoms, including fatigue, pain, numbness, and tingling in their extremities as well as weakness. The symptoms were described as more sensory than motor, and all patients had evidence of polyradiculoneuropathy with signs of nerve root irritation. An epidemiological investigation revealed that the only commonality between cases was their exposure to a pork brain extraction procedure involving compressed air. As relatives of the cases remained asymptomatic and all cultures for known pathogens were negative, the etiology of the syndrome seemed not to be infectious. Clinically, the syndrome was most akin to chronic inflammatory demyelinating polyneuropathy. Laboratory tests corroborated the clinical findings, revealing inflammation of peripheral nerves and nerve roots; however, these cases also had features clinically distinct from chronic inflammatory demyelinating polyneuropathy as well as laboratory testing revealing a novel immunoglobulin G immunostaining pattern. This suggested that the observed inflammation was the result of 1 or more unidentified antigens. This syndrome was ultimately dubbed progressive inflammatory neuropathy and was theorized to be an autoimmune reaction to aerosolized porcine neural tissue. Since the investigation's outset, 18 cases of progressive inflammatory neuropathy have been identified at the Minnesota pork processing plant, with 5 similar cases at an Indiana plant and 1 case at a Nebraskan plant. The plants in which cases have been identified have since stopped the use of compressed air in removing pork brains. All cases have stabilized or improved, with some requiring immunosuppressive and analgesic treatment. The study of progressive inflammatory neuropathy is ongoing, and the details of this investigation highlight the value of epidemiological principles in the identification and containment of outbreaks while researchers attempt to uncover the unique pathophysiology and potential etiology of the illness. Mt Sinai J Med 76:442-447, 2009. (c) 2009 Mount Sinai School of Medicine.
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PMID:Outbreak of progressive inflammatory neuropathy following exposure to aerosolized porcine neural tissue. 1978 53