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Query: UMLS:C0015672 (fatigue)
 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

There is some evidence that the fatiguing characteristics during isometric back extension tasks may assist in identifying differences between individuals with and without low back pain (LBP). During these tasks, especially in standing, other abdominal trunk muscles are also active. The abdominal trunk muscles acting across multiple segments of the lumbar spine function in isolation or in synergy to create flexion torques. It is suggested that co-activation patterns of the trunk muscles are able to control the axis of rotation of the extension torque and also provide multi-segmental stability of the spine. The purpose of this study was to examine the fatigue responses in 4 asymptomatic individuals to a sustained isometric extension task of the trunk muscles evaluating the shifts in the median frequency of the electromyographic (EMG) signal. This study suggests that in asymptomatic subjects, the more superficial abdominal muscles (External Oblique and Rectus Abdominis) increased in activity as the test progressed. There was large inter-individual variation in both amplitude and median frequency changes. Rectus abdominis and the back extensors demonstrated characteristics of fatigue during the task. Studies to test for any characteristic trends in whether specific trunk muscles fatigue in standing is a feature in chronic LBP, invites a formal investigation.
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PMID:Trunk muscle fatigue during a back extension task in standing. 1167 32

Two cases of solitary plasmacytoma of bone (SPB) were diagnosed. The first case was a 41-year-old woman, complaining of fatigue from her lumbar region to her legs. The second case was a 56-year-old man complaining of poor gait and severe lumbago with numbness in the toes of both feet. Magnetic resonance imaging showed the osteolytic lesion in the 12th thoracic bone in the first patient and around the 2nd, 3rd and 4th lumbar bones in the second patient. In both patients serum analysis revealed the monoclonal component of immunoglobulin G (IgG) protein with kappa-light chain, and considering this and other findings SPB was diagnosed. Both patients were first treated with irradiation around the involved bone and then with a course of chemotherapy. In the first patient the tumour region of the bone was surgically removed and replaced with a ceramic spacer. The symptoms of both patients were ameliorated, and the patients remained in good condition for around 3 years without conversion to multiple myeloma. In view of the overall effectiveness of treatments for SPB, our therapeutic strategy deserves careful evaluation.
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PMID:A therapeutic strategy for isolated plasmacytoma of bone. 1167 11

Electromyographic (EMG) analysis has been used successfully to identify back muscle impairment in patients with low back pain. EMG signals from normal subjects during axial spinal unloading using an LTX 3000 device were obtained and spectral parameters of the electromyographic (EMG) signal were analyzed. The purpose of the study was to determine the optimal time for effective traction using the LTX 3000 rehabilitation device. These data will serve as a baseline for future studies to help assess back muscle function in low back patients undergoing rehabilitation. Three time points during axial spinal unloading were compared to pre-unloading to detect alterations in median power frequency (MPF), root-mean-square (RMS) and rectified integrated EMG (riEMG) during axial spinal unloading. There were reductions of riRMG during 0-10 minutes of axial spinal unloading in all muscle groups, followed by an increase in riEMG value from 10 to 15 minutes. A similar trend was seen in the RMS values. The MPF did not change during the course of unloading, indicating that there was likely no change in fatigue properties of the paraspinal muscles during axial spinal unloading. The optimal time for effective axial spinal unloading on the basis of muscle activity was determined to be 10 minutes of axial spinal unloading, and a back assessment procedure was presented that uses surface EMG electrodes to objectively characterize muscle activity and relative fatigue properties. Future studies will use this methodology to assess treatment outcome in a chronic low back pain population.
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PMID:Surface EMG activity of the back musculature during axial spinal unloading using an LTX 3000 Lumbar Rehabilitation System. 1172 Dec 97

We report a case of recurrent pyogenic vertebral osteomyelitis associated with type 2 diabetes mellitus. A 51-year-old male was admitted to our hospital because of lumbago and general fatigue, with multiple ulcers on the soles of his feet. Staphylococcus aureus was isolated from peripheral blood and the foot ulcers, and 67Gallium scintigram showed abnormal isotope uptake, accumulated at the lower thoracic spine. Antibiotics were administered and the patient underwent intensive insulin therapy. Magnetic resonance imaging (MRI), performed after the levels of C-reactive protein decreased to 0.0 mg/dl, indicated old inflammatory changes at the Th8-Th9 spine and antibiotics were stopped. Unexpectedly, 8 days later the patient complained of lumbago with fever again, and MRI showed acute inflammatory changes at the same lesion site. This case report suggests that it is important for complementary antibiotic therapy to continue after signs of inflammation have disappeared in cases of pyogenic vertebral osteomyelitis.
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PMID:Recurrent pyogenic vertebral osteomyelitis associated with type 2 diabetes mellitus. 1172 34

The purpose of this study was to assess different measurement strategies to increase the reliability of different electromyographic (EMG) indices developed for the assessment of back muscle impairments. Forty male volunteers (20 controls and 20 chronic low back pain patients) were assessed on three sessions at least 2 days apart within 2 weeks. Surface EMG signals were recorded from four pairs (bilaterally) of back muscles (multifidus at the L5 level, iliocostalis lumborum at L3, and longissimus at L1 and T10) while the subjects performed, in a static dynamometer, two static trunk extension tasks at 75% of the maximal voluntary contraction separated by a 60 s rest period: (1) a 30 s fatigue task and (2) a 5 s recovery task. Different EMG indices (based on individual muscles or averaged across bilateral homologous muscles or across all muscles) were computed to evaluate muscular fatigue and recovery. Intra-class correlation coefficient (ICC) and standard error of measurement (SEM) in percentage of the grand mean were calculated for each EMG variable. Reliable EMG indices are achieved for both healthy and chronic low back pain subjects when (1) electrodes are positioned on medial back muscles (multifidus at the L5 level and longissimus at L1) and (2) measures are averaged across bilateral muscles and/or across two fatigue tests performed within a session. The most reliable EMG indices were the bilateral average of medial back muscles (ICC range: 0.68-0.91; SEM range: 5-35%) and the average of all back muscles (ICC range: 0.77-0.91; SEM range: 5-30%). The averaging of measures across two fatigue tests is predicted to increase the reliability by about 13%. With regards to EMG indices of fatigue, the identification of the most fatigable muscle also lead to satisfactory results (ICC range: 0.74-0.79; SEM range: 21-26%). The assessment of back muscle impairments through EMG analysis necessitates the use of multiple electrodes to achieve reliable results.
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PMID:Evaluation of measurement strategies to increase the reliability of EMG indices to assess back muscle fatigue and recovery. 1195 81

Few studies have examined the effect of pain on the quality of life of individuals with slowly progressive neuromuscular disease (NMD). The purpose of this study was to determine the frequency and extent to which subjects with slowly progressive NMD report pain and the association between pain and health-related quality of life in persons with NMD. The study design was a descriptive, nonexperimental survey. Of a total of 1,432 subjects with slowly progressive NMDs recruited from a university-based NMD clinic and the membership rosters of worldwide NMD support organizations, 859 agreed to participate. The primary measurement tool used was the Medical Outcomes Study SF-36 health survey. Our results indicated that, with the exception of adult spinal muscular atrophy (SMA), the frequency and severity of pain reported in slowly progressive NMDs was significantly greater than levels of pain reported by the general US population and was comparable to pain reported by subjects with osteoarthritis and chronic low back pain. There was a significant correlation between increased pain and lower levels of general health, vitality, social function, and physical role. Pain was moderately associated with increased fatigue, inability to cope adequately with stress, and sleep disturbance. In conclusion, with the exception of adult SMA, the frequency and severity of pain reported in slowly progressive NMDs was significant.
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PMID:Assessment of pain and health-related quality of life in slowly progressive neuromuscular disease. 1217 12

Paraspinal electromyographic (EMG) activity was recorded bilaterally from three lumbar levels during 30-s isometric trunk extensions [40 and 80% of maximum voluntary contraction (MVC)] in 20 healthy men and 14 chronic low back pain patients in pain. EMG parameters indicating neuromuscular fatigue and contralateral imbalances in EMG root-mean-square amplitude and median frequency were analyzed. Patients in pain showed less fatigue than controls at both contraction levels and produced only 55% of their MVC. Patients in pain likely did not produce a "true" maximum effort. A low MVC estimate would mean lower absolute contraction levels and less neuromuscular fatigue, thus explaining lower scores in the patients. Contralateral root-mean-square amplitude imbalances were present in both categories of subjects although such imbalances, when averaged across lumbar levels, were significantly larger in patients. Median frequency imbalances were significantly larger in the patients, at segmental as well as across lumbar levels. These results suggest that the presence of pain in these patients caused a redistribution of the activation behavior between synergistic muscles of the lumbar back.
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PMID:Activation imbalances in lumbar spine muscles in the presence of chronic low back pain. 1248 60

Noxious stimuli and painful disorders interfere with sleep, but disturbances in sleep also contribute to the experience of pain.Chronic paroxysmal hemicrania and possibly cluster headaches are related to REM sleep. Whereas headache is associated with snoring and sleep apnea, morning headaches are not specific for any primary sleep disorder. Nevertheless, the management of the sleep disorder ameliorates both morning headache and migraine.Noxious stimuli administered into muscles during slow-wave sleep (SWS) result in decreases in delta and sigma but an increase in alpha and beta EEG frequencies during sleep. Noise stimuli that disrupt SWS result in unrefreshing sleep, diffuse musculoskeletal pain, tenderness, and fatigue in normal healthy subjects. Such symptoms accompany alpha EEG sleep patterns that often occur in patients with fibromyalgia. The alpha EEG patterns include phasic and tonic alpha EEG sleep as well as periodic K alpha EEG sleep or frequent periodic cyclical alternating pattern. Moreover, alpha EEG sleep, as well as sleep-related breathing disorder and periodic limb movement disorder, occur in some patients with fibromyalgia, rheumatoid arthritis and osteoarthritis. Depression and not alpha EEG sleep are features of somatoform pain disorder. Disturbances in sleep, pain behaviour and psychological distress influence return to work in workers who have suffered a soft tissue injury, e.g. low back pain. Patients with irritable bowel disorder have disturbed sleep and have increased REM sleep. In conclusion, there is a reciprocal relationship between sleep quality and pain. The recognition of disturbed or unrefreshing sleep influences the management of painful medical disorders.
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PMID:Sleep and pain. 1253 Oct 4

Three basic classification schemes have been developed to categorize spondylolisthesis, the slippage or forward displacement of one vertebra over another. Two rely on radiographic appearance, and the third stresses the developmental aspect of the pathology. The pathology is relatively rare in individuals younger than 18 years, appears to be influenced by race, and is found more frequently in males than females and in patients with symptomatic low back pain. Lytic spondylolisthesis occurs more frequently at certain spinal levels, and certain sports activities have been implicated in its development. The etiology remains unclear, but hereditary factors are unlikely with no evidence of the lytic defect in newborns. Recent research indicates that the architecture of the pelvis may be an important parameter. Some have postulated that the underlying pathomechanical event is a fracture, either acute or secondary to fatigue. Once the pars defect has been created, anatomic and biomechanical forces conspire to prevent healing of the fracture and create a spondylolisthesis. Although mechanical considerations are likely most significant, genetic considerations have also been discussed. All the imaging modalities play useful roles in defining the pathoanatomy, including diskography. Patients typically report symptoms as back pain and/or neurologic symptoms; however, these symptoms can have other causes even though a spondylolisthesis is present. A thorough history and physical examination, along with the radiographic investigations, are essential to determining proper treatment. Nonsurgical options are activity modification, bracing, physical therapy, and intervention in the form of medications or injections. Use of muscle relaxers and narcotics may be appropriate for managing initial acute pain. Surgical options are direct repair of the pars defect, decompression, fusion, or a combination of these procedures. The various techniques of pars repair are recommended only for patients younger than 30 years. Although decompression alone may be suitable in some situations, decompression with fusion is more standard, certainly when instability and low back pain exist.
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PMID:Low-grade isthmic/lytic spondylolisthesis in adults. 1269 Aug 77

The timing of trunk muscle activation has become an important element in the understanding of human movement in normal and chronic low back pain populations. The detection of anticipatory postural adjustment via trunk muscle onsets from electromyographic (EMG) signals can be problematic due to baseline noise or electro-cardiac (ECG) artefact. Shewhart protocols or whole signal analyses may show different degrees of sensitivity under different conditions. Muscle activity onsets were determined from surface EMG of seven muscles for five trials before and after fatigue were examined in four subjects (n=280). The objective of this study was to examine two detection methods (Shewhart and integrated protocol (IP)) in determining the onsets of trunk muscles. The variability of the baseline amplitude and the impact of added Gaussian noise on the detected onsets were used to test for robustness. The results of this study demonstrate that before and after fatigue there is a large degree of baseline variance in the trunk muscles (coefficients of variation between 40-65%) between trials. This could be normal response to body sway. The IP method was less susceptible to false onsets (detecting onsets in the baseline window) 3 vs. 51%. The findings suggest the IP method is robust with large variance in the baseline if the signal to noise ratio is greater than six. In spite of the robustness of the algorithm, the findings would suggest that statistical assessments should be used to target trials for selective visual inspection for subtle trunk muscle onsets.
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PMID:Trunk muscle onset detection technique for EMG signals with ECG artefact. 1270 1


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