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Query: UMLS:C0015672 (fatigue)
 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

As part of its investigation of the EXXON VALDEZ tankship accident and oil spill, the National Transportation Safety Board (NTSB) examined the master's speech for alcohol-related effects. Recorded speech samples were obtained from marine radio communications tapes. The samples were tested for four effects associated with alcohol consumption is available scientific literature: slowed speech, speech errors, misarticulation of difficult sounds ("slurring"), and audible changes in speech quality. It was found that speech immediately before and after the accident displayed large changes of the sort associated with alcohol consumption. These changes were not readily explained by fatigue, psychological stress, drug effects, or medical problems. Speech analysis appears to be a useful technique to provide secondary evidence of alcohol impairment.
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PMID:Speech analysis as an index of alcohol intoxication--the Exxon Valdez accident. 193 83

The present study systematically compared the effects of fatigue and alcohol intoxication on a range of neurobehavioural tasks. By doing so, it was possible to quantify the performance impairment associated with fatigue and express it as a blood alcohol impairment equivalent. Twenty-two healthy subjects aged 19-26 years participated in three counterbalanced conditions. In the sustained wakefulness condition, subjects were kept awake for 28 h. In the alcohol and placebo conditions, subjects consumed either an alcoholic or non-alcoholic beverage at 30 min intervals, until their blood alcohol concentration reached 0.10%. In each session, performance was measured at hourly intervals using four tasks from a standardised computer-based test battery. Analysis indicated that the placebo beverage did not significantly effect mean relative performance. In contrast, as blood alcohol concentration increased performance on all the tasks, except for one, significantly decreased. Similarly, as hours of wakefulness increased performance levels for four of the six parameters significantly decreased. More importantly, equating the performance impairment in the two conditions indicated that, depending on the task measured, approximately 20-25 h of wakefulness produced performance decrements equivalent to those observed at a blood alcohol concentration (BAC) of 0.10%. Overall, these results suggest that moderate levels of fatigue produce performance equivalent to or greater than those observed at levels of alcohol intoxication deemed unacceptable when driving, working and/or operating dangerous equipment.
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PMID:Quantifying the performance impairment associated with fatigue. 1064 65