Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0015672 (fatigue)
 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The relationship between background characteristics, stress, reported symptoms and clinical findings was studied in a group comprising 333 patients with Myofascial Pain Dysfunction Syndrome (MPD). Three-quarters of this clientele were women, most of them of young or middle age. The stressors most frequently reported were pressed working conditions, anxiety and frustration deriving from disease, and family problems. Of the symptoms, pain was reported by 78 percent of the patients, clicking by 53 percent, limitation of movement by 44 percent and feeling of stiffness and fatigue of masticatory muscles by 41 percent. Significant correlations were found between a number of variables, of which the close relationship between perceived pressors and muscle groups painful to palpation was considered to be a paramount importance. The data were combined into a hypothetic model postulating causal relations. The model was intended for testing and modification in coming studies.
 ...
PMID:Relationship between sociomedical factors and TMJ-symptoms in Norwegians with myofascial pain-dysfunction syndrome. 26 66

The Committee on Cervicobrachial Syndrome in Japan Association of Industrial Health (JAIH) made a report on the questionnaires for checking for the complaints of patients suffering from Occupational Cervicobrachial Disorder (OCD). In order to reveal how the complaints develop in the progress of OCD, we analysed the complaints of 117 workwomen in assembly lines of a cigarette factory by using the questionnaires. And the followings were made clear: 1) At the mild stage of OCD, stiffness or dullness at the neck and shoulders, and eyestrain become remarkable. 2) At the moderate stage, pain at the neck, shoulders, arms and hands, dullness at extremities, general fatigue, pain or heavy feeling in the head, increased irritability etc. become remarkable in addition to the mild stage complaints. 3) At the severe stage, pain and dullness at the back, numbness at arms and hands, hand coldness, sleep disturbance etc. become remarkable in addition to the moderate stage complaints. 4) Various sufferings in daily life such as "I want to lie down at rest time," "I lack patience to go on reading long," "It is hard for me to go on writing long," and "Fixed sitting soon tires me" become more and more frequent as the stage advances. We consider it is important in the diagnosis of OCD to pay attention to the general symptoms such as general fatigue, pain or heavy feeling in the head, increased irritability and sleep disturbance, together with complaints at the neck, shoulders, arms and hands.
 ...
PMID:Studies on the progress of occupational cervicobrachial disorder by analysing the subjective symptoms of work-women in assembly lines of a cigarette factory. 52 87

Orofacial manifestations in cases of Myofascial Pain Dysfunction Syndrome (MPD) diagnosed amongst 71 Dental patients were studied in detail. Findings of this study show that the chief complaint and associated orofacial manifestations of MPD are related to muscular hypertonicity. Stressful situations may produce muscular hypertension, which leads to muscle tenderness as a symptom of over work and fatigue. MPD may be considered a psycosomatic disease.
 ...
PMID:Orofacial manifestations of myofascial pain dysfunction syndrome amongst dental patients. 209 59

The contemporary behavior analyst, to operate ethically and effectively, must be aware of many more factors affecting behavior than simple consequences. Although the literature demonstrating the effectiveness of active behavior management is impressive, a compelling argument can be made that a great number of behavior problem seen in individuals with developmental disabilities may be attributable to factors other than consequences. Our experience has been more often than not that physiological, organic, medication, or situational variables are the actual culprits in maladaptive behavior. Individuals with severe or profound retardation may respond to aversive features of their environment by displaying noncompliance, tantrums, aggression, or self-injurious behavior. These antecedents can affect their behavior just as powerfully as can the consequences of their behavior. Behavior analysts must become sensitive to these potential factors and be prepared to employ behavioral diagnostic strategies in the search for the causes of maladaptive behavior. Finally, they must be prepared to design rather unconventional passive behavior management treatment programs involving the manipulation of the antecedent environment. In the case of Carrie, from the example at the beginning of this paper, the analysis yielded the hypothesis that her face scratching was a reaction to sinus blockage caused by seasonal allergies. Her treatment involved daily dosages of antihistamines administered by our nurses and subsequent elimination of the scratching. Tom was found to be suffering from "wheelchair fatigue." When he was allowed to recline on other surfaces (e.g., bean bag chair, mat, bolster) on a regular basis, he did not attempt any form of self-injury. Melissa was found to have a severe case of Pre Menstrual Syndrome as well as seizure disorder, and was treated with the appropriate medications. Her headbanging was reduced to a few minor incidents per month. Walter's tantrums on closer inspection seemed part of a chain of behavior leading to seizure-like attacks. Preliminary evidence suggests that when he is treated with phenobarbital the tantrums and aggression disappear. And finally, Debbie was found to be very sensitive to a variety of discomforting events. She would cry, sob, and scream when she was wet, thirsty, hungry, and tired. Changing her regularly, offering her water every hour and extra snacks in the morning as well as short naps in the early afternoon eliminated the crying and sobbing. She now participates with the other clients and seems to enjoy the house activities.(ABSTRACT TRUNCATED AT 400 WORDS)
 ...
PMID:Behavioral diagnostics. 274 44

This paper comprises a short summary of the immune system function with particular emphasis on the red blood cells' function in immunity. The basic biochemical features of Post Viral Fatigue Syndrome, Non-Antibody mediated Allergy, Autoimmunity and Immune deficiency is described and treatment procedure using Nutritional Medicine suggested.
 ...
PMID:A brief review of the immune system and its function in relation to: PVFS, non-antibody mediated allergy, autoimmunity and immune deficiency. 305 38

Sleep disturbances commonly occur in the premenstruum in both Premenstrual Syndrome (PMS) patients and in women from the general population. Reports on the Post-Sleep Inventory were obtained from a clinic sample of PMS patients and samples from the general population dichotomized into a non-clinic group with and without premenstrual disturbance on the basis of their scores on the Premenstrual Tension Syndrome Self Rating Scale. The patients reported degrees of disturbance that were consistently higher than either or both the other two groups. PMS patients reported unpleasant dreams, awakenings, failure to wake at the expected time and tiredness in the morning, and heightened mental activity during the night and upon awakening. The three groups could be reliably discriminated on this basis with an overall accuracy of 82%. Sleep disturbances form an important component of premenstrual disturbance and merit specific clinical intervention and more detailed investigation.
 ...
PMID:Sleep in the premenstrual phase: a self-report study of PMS patients and normal controls. 317

Fatigue is the commonest, yet least understood and most neglected symptom in medicine. A physiological formula for fatigue is proposed, based on the concept of a reduction of the "latent capacity" of cells, tissues and organs whose states are constantly monitored by the brain. Reduced "latent capacity" is postulated as being the sought-after, non-specific alarm signal of the General Adaptation Syndrome of Selye (G.A.S.). The relationship between fatigue and pain is discussed. Reduced "latent capacity" is postulated as being the common thread in the different kinds of fatigue - physiological, pathological, psychogenic, acute and chronic.
 ...
PMID:Fatigue: towards an analysis and a unified definition. 741 41

This article represents the contributions of the panel on "Neuropsychiatric Syndromes and Psychological Symptoms" of the National Cancer Institute of Canada Workshop on Symptom Control and Supportive Care in Patients with Advanced Cancer. The panel's presentations focused on mood disorders and cognitive disorders, and described the current state of knowledge regarding prevalence, assessment, and intervention. Recommendations for future research are presented based on a consensus of the panel as to the need to fill glaring gaps in our current state of knowledge, and a desire to improve the quality of research in this area of palliative medicine. Recommendations for future research on neuropsychiatric symptoms and syndromes in palliative care include (1) adoption of uniform terminology (taxonomy of disorders) and diagnostic classification systems, (2) utilization of existing validated tools and measures in prevalence and intervention research, (3) development of new tools and measures that are more applicable and relevant to the palliative care setting, (4) encouragement for studies of the prevalence of neuropsychiatric symptoms and syndromes, (5) promotion of intervention studies utilizing pharmacologic and nonpharmacologic treatments for depressive disorders and cognitive disorders in advanced cancer patients, and (6) expansion of the focus of such research to other neuropsychiatric disorders (for example, anxiety disorders, posttraumatic stress disorders, and sleep disorders), symptoms (fatigue and tension) and related issues (suicidal ideation and desire for hastened death).
 ...
PMID:Neuropsychiatric syndromes and psychological symptoms in patients with advanced cancer. 773 Jun 85

Chronic Fatigue Immune Dysfunction Syndrome (CFIDS) is estimated to affect 2 to 5 million people in the United States. Despite its high incidence, persons with CFIDS have been neglected by the medical community mainly because there is no singular confirming diagnostic test or proven effective treatment. The CFIDS population is incorrectly stereotyped as upper-middle-class, white, female hypochondriacs; consequently, symptoms often are belittled or ignored. In reality, CFIDS is a severe medical condition that affects women, men, and children of any race and often causes long-term or total disability. The results of a modified functional capacity evaluation developed by the author and completed on 86 persons with CFIDS between 1988 and 1990 confirm that this population has severe physical and cognitive disabilities that affect their professional, familial, and social lives. The results of these evaluations are used to present a profile of persons with CFIDS that can serve as a basis for understanding this population and for guiding intervention.
 ...
PMID:Functional capacity evaluations of persons with chronic fatigue immune dysfunction syndrome. 778 15

Syndromes characterized by chronic pain and fatigue have been described in the medical literature for centuries. Fibromyalgia is the term currently used to describe this symptom complex, and considerable research has been performed in the last decade to delineate the epidemiology, pathophysiology, and genesis of this entity. Although fibromyalgia is defined by its musculoskeletal features, it is clear that there are a large number of non-musculoskeletal symptoms, such that we now understand that there is considerable overlap with allied conditions such as the chronic fatigue syndrome, migraine and tension headaches, irritable bowel syndrome, and affective disorders. This article will review our current state of knowledge regarding fibromyalgia and these allied conditions, and present a unifying hypothesis that describes both the pathophysiology of symptoms and the genesis of these disorders.
 ...
PMID:The pathogenesis of chronic pain and fatigue syndromes, with special reference to fibromyalgia. 858 67


1 2 3 4 5 6 7 8 9 10 Next >>