Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0015672 (
fatigue
)
51,768
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Paroxysmal Choreoathetosis (PC) is a rare disorder which is characterized by spells of involuntary movements of the limbs, the head and the trunk lasting from a minute to several hours. PC is classified in two main types. In Paroxysmal Dystonic Choreoathetosis (PDC) the attacks are prolonged and precipitated by alcohol, emotion or
fatigue
, in Paroxysmal Kinesigenic Choreoathetosis (PKC) the attacks last less than 5 minutes and are precipitated by sudden movements. Although the pathophysiology of the disorder ist still uncertain, it is supposed to be an
extrapyramidal disorder
. Clinical features, therapeutical and differential diagnostic aspects are discussed. There is a certain risk that the disorder is misinterpreted as psychogenic or hysterical in nature. The mostly good response to medication can help the patients avoid superimposed emotional problems.
...
PMID:[Paroxysmal choreoathetosis]. 188 21
