Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0014848 (achalasia)
 2,804 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 179
AAAS 61
She 60
proton pump 42
reserved 40
ACTH 35
gut 34
beta-endorphin 22
calcium channel 22
Mol 19
POEM 18
gastrin 13
nitric oxide synthase 12
ACTH receptor 11
ACG 10
p53 9
HLA 9
adrenocorticotropic hormone 8
nuclear pore protein 7
MRI 7
polypeptide 7
insulin 6
MIM 6
somatostatin 5
ENT 5
axonal 5
substance P 5
cytokine 5
Alport syndrome 5
collagen 5
acetylcholinesterase 5
Pol 5
HLA class II 4
AAA 4
vasoactive intestinal peptide 4
San 4
nucleoporin 4
vasoactive intestinal peptide (VIP) 4
nodal 4
PABPN1 4
X-linked 3
guanylyl cyclase 3
neuropeptide Y 3
CD4 3
enigma 3
IFN 3
RET 3
CO2 3
c-kit 3
Vasoactive intestinal peptide 3
melanocortin 2 receptor 3
IRP 3
CD8 3
secretin 3
PGP 9.5 3
phosphodiesterase 3
GMPPA 3
version 3 3
DES 3
pancreatic polypeptide 3
ATP 3
neuronal nitric oxide synthase 3
novel gene 3
S100 2
neuron-specific enolase 2
mast cell 2
lacrimal 2
HLA-DQ 2
calcitonin 2
eosinophil cationic protein 2
strabismus 2
KIT 2
CD20 2
COL4A6 2
Gen 2
HLA-DR 2
VIP 2
calcineurin inhibitor 2
DQB1 2
WD-repeat protein 2
enolase 2
type II keratin 2
beta 1 2
Neuropeptide Y 2
JAMA 2
glucagon 2
cholecystokinin 2
DQ1 2
anonymous 2
GUCY1A3 2
COL4A5 2
rhabdomyosarcoma 2
non-Hodgkin's lymphoma 2
thyroid stimulating hormone 2
ALD 2
p21 2
GMPPB 2
glutamic acid decarboxylase 2
MRAP 2
5-hydroxytryptamine 2
Hop 2
guanylate cyclase 2
GIF 2
neurofibromatosis 2
lymphoid 2
factor VIII 1
alpha-fetoprotein 1
POLG 1
eosinophil major basic protein 1
DQA1 1
ARMS 1
Pseudomonas 1
MHC 1
thyroglobulin 1
LHX4 1
CGRP 1
DIC 1
IL10 1
FISH 1
PRA 1
transgelin 1
catalase 1
AAS 1
VIII 1
aquaporin-4 1
synapsin I 1
TCS 1
CPR 1
lamin A 1
HPD 1
peroxidase 1
neural cell adhesion molecule 1
phosphatase 1
nitric oxide synthase 1 1
dilute 1
prostate-specific membrane antigen 1
tumor necrosis factor alpha 1
alpha-1 antitrypsin 1
CYP11A1 1
HD1 1
TNF 1
CAS 1
Ki-67 1
MAS 1
keratin 1
UDP-glucuronyltransferase 1
epithelial cadherin 1
TPIT 1
Smith-Lemli-Opitz syndrome 1
BID 1
autosomal recessive) 1
CSI 1
PEF 1
SPA 1
human leukocyte antigen class II 1
HLA DQA1 1
SCL 1
C30 1
coagulation factor VIII 1
gonadotropin deficiency 1
more...
Disease
achalasia 2804
dysphagia 853
Heller 499
gastroesophageal reflux disease 456
Esophageal 379
esophageal spasm 194
cancer 174
esophagitis 169
Esophagus 158
Esophagus 158
carcinoma 117
tumor 116
adrenal insufficiency 93
hiatal hernia 84
AAA 84
megaesophagus 72
Barrett's esophagus 66
esophageal cancer 64
Chagas 59
esophageal cancer 59
reflux esophagitis 59
squamous cell carcinoma 59
scleroderma 56
adenocarcinoma 54
gastroparesis 47
esophageal dysmotility 47
dysplasia 32
aspiration pneumonia 31
failure to thrive 27
esophageal stricture 26
rare disease 24
neuropathy 23
asthma 21
carcinoma of the esophagus 20
Zenker's diverticulum 20
esophageal varices 19
irritable bowel syndrome 19
diabetes 19
pneumonia 19
malnutrition 18
obesity 18
dyspepsia 17
autonomic neuropathy 17
leiomyoma 17
megacolon 16
mental retardation 16
mental retardation 16
mediastinitis 15
duodenal ulcer 15
hernia 14
pneumothorax 14
anorexia nervosa 14
anal fissure 14
emphysema 13
Down syndrome 13
muscular atrophy 13
sepsis 13
Parkinson's disease 13
celiac disease 12
Esophageal perforation 12
stroke 12
gastric cancer 12
sepsis 12
neuromuscular disorder 12
peptic ulcer 12
paraesophageal hernia 12
metastases 12
dyskinesia 11
varices 11
empyema 11
amyloidosis 10
West 10
hypertension 10
incontinence 10
esophageal atresia 9
morbid obesity 9
inflammatory bowel disease 9
PSS 9
herpes simplex 9
Mycobacterium 9
Thoracic 9
Crohn's disease 9
Eosinophilic esophagitis 8
Best 8
Syndrome 8
ileus 8
optic atrophy 8
sarcoidosis 8
incontinence 8
Schatzki's ring 8
neurological disease 8
lymphoma 8
peripheral neuropathy 8
polyneuropathy 8
Alport syndrome 8
lung carcinoma 8
bowel obstruction 7
enterocolitis 7
gastrointestinal disease 7
chylothorax 7
rheumatoid arthritis 7
genetic disorder 7
bronchiectasis 7
gallstones 7
tylosis 7
dementia 7
hypoglycemia 7
organic disease 7
Esophageal squamous cell carcinoma 7
Oropharyngeal dysphagia 7
infectious diseases 6
cold 6
virus infection 6
familial dysautonomia 6
SEM 6
multiple endocrine neoplasia 6
Plummer-Vinson syndrome 6
esophageal candidiasis 6
Esophageal dysphagia 6
eosinophilia 6
anemia 6
dysphonia 6
respiratory failure 6
pancreatitis 6
dysphasia 6
tuberculosis 6
amyotrophic lateral sclerosis 5
mesothelioma 5
carcinogenesis 5
bulimia nervosa 5
dysautonomia 5
systemic disease 5
deafness 5
motor neuron disease 5
leiomyosarcoma 5
Nutcracker esophagus 5
lung cancer 5
coronary artery disease 5
Zollinger-Ellison syndrome 5
recurrent pneumonia 5
eating disorder 5
gastric ulcer 5
myopathy 5
heart failure 5
peritonitis 5
Hodgkin's disease 5
depression 5
fecal incontinence 5
Adenocarcinoma 5
herpes 5
xerostomia 5
Esophageal adenocarcinoma 5
strabismus 5
Addison's disease 5
autoimmune disease 5
cirrhosis 5
adenocarcinoma of the stomach 4
respiratory disease 4
portal hypertension 4
melanoma 4
more...
Symptom
regurgitation 202
chest pain 200
pain 111
heartburn 98
vomiting 94
cough 46
anesthesia 44
spasm 42
constipation 42
weakness 21
respiratory distress 17
discomfort 17
discomfort 17
diarrhea 16
chronic constipation 15
stridor 15
dyspnea 14
abdominal pain 14
angina 12
dystonia 12
fatigue 10
epigastric pain 9
nausea 9
incoordination 8
belching 7
blepharospasm 7
spasticity 7
ataxia 7
hoarseness 7
dysarthria 6
wheezing 6
cerebellar ataxia 5
chronic cough 5
cyanosis 5
syncope 5
seizures 5
Respiratory symptoms 5
ENT 5
Regurgitation 4
anorexia 4
headache 4
bloating 4
Gastrointestinal symptoms 3
tremor 3
abdominal discomfort 3
cachexia 3
nausea and vomiting 2
shortness of breath 2
nocturnal cough 2
starvation 2
drooling 2
paresis 2
hypotonia 2
productive cough 2
excessive sweating 2
analgesia 2
Non-cardiac chest pain 2
acidity 2
asthenia 2
Motor dysfunction 2
collapse 2
dry eye 2
back pain 2
hyperemesis gravidarum 2
hypertonia 2
paraparesis 1
splenomegaly 1
CSR 1
exertional dyspnea 1
aphagia 1
No adverse effect 1
nasal discharge 1
neurological disability 1
numbness 1
dysesthesia 1
dizziness 1
bladder pain 1
retrosternal discomfort 1
rhinorrhea 1
dysuria 1
emaciation 1
retching 1
tinnitus 1
enuresis 1
right upper quadrant pain 1
Air trapping 1
abdominal fullness 1
arthralgia 1
abnormal gait 1
myoclonus 1
tachypnea 1
Wind 1
flushing 1
rales 1
Muscle fibrosis 1
halitosis 1
sore throat 1
hemiplegia 1
hemoptysis 1
Thoracic pain 1
hepatomegaly 1
erythema 1
muscular incoordination 1
chest tightness 1
Deglutitive inhibition 1
hypercapnia 1
thinning 1
vertigo 1
overweight 1
hypoproteinemia 1
hypothermia 1
atypical chest pain 1
Retrosternal pain 1
acute abdomen 1
colic 1
Spastic 1
chills 1
muscle rigidity 1
inanition 1
persistent cough 1
painful swallowing 1
Drug
Cardiovasc 34
Botox 19
Monit 5
BOTOX 5
ENT 5
nitroglycerin 5
Lugol 4
EDR 3
Atropine 3
Hypaque 2
Zmax 2
Buscopan 2
Azithromycin 2
Diphenhydramine 2
BoNT/A 1
Glucagon 1
Gastro 1
Edrophonium chloride 1
Histalog 1
Dial 1
Coral 1
lysine 1
Nesiritide 1
CPR 1
IL-2 1
Dihydroergotamine 1
CSF 1
Scopolamine 1
Vicryl 1
Dakar 1
Leaf 1
Allergen 1
Ferrous sulfate 1
Asthma 1
CSI 1
Prednisone 1
Omeprazole 1
Histalog 1
Enzyme
NO synthase 7
ERK 6
guanylate cyclase 5
NADPH-diaphorase 5
acetylcholinesterase 5
botulinum neurotoxin 4
NOS 4
phosphodiesterase 3
cholinesterase 3
enolase 2
catalase 1
protein kinase C 1
adenylate cyclase 1
MCS 1
peroxidase 1
dihydropyrimidine dehydrogenase 1
PRA 1
protein phosphatase 2A 1
mitogen-activated protein kinase 1
hypoxanthine-guanine phosphoribosyltransferase 1
UDP-glucuronosyltransferase 1
transhydrogenase 1
luciferase 1
dopamine beta-hydroxylase 1
GDP-mannose pyrophosphorylase 1
renin 1
CPR 1
ubiquitin-protein ligase 1
creatine kinase 1
granzyme B 1
glutathione reductase 1
protein kinase 1
alkaline phosphatase 1
myosin light chain kinase 1
prostate-specific membrane antigen 1
dihydropyrimidine dehydrogenase 1
DNA polymerase 1
Compound
barium 251
Clin 239
Dec 172
water 45
ACTH 35
calcium 34
nitric oxide 30
DNA 20
His 17
CO2 12
Nifedipine 9
sulfate 7
mercury 6
sodium 6
PPI 6
iodine 5
Neuronal 5
phosphate 5
cGMP 5
aldosterone 5
galactose 4
nitrate 4
AAA 4
arginine 4
bromide 4
oxygen 4
IPN 3
Cardiol 3
Adrenal 3
Asp 3
HCl 3
Luminal 3
Salix 3
ISDN 3
DES 3
Atropine 3
Sildenafil 3
ATP 3
Edrophonium 3
Estrogen 3
potassium 2
cysteine 2
tryptophan 2
Insulin 2
Allergan 2
aspartic acid 2
cAMP 2
Pentagastrin 2
Verapamil 2
CIT 2
aspartic acid 2
salt 2
5-FU 2
DQ1 2
tryptophan 2
tryptophan 2
tyrosine 2
Diphenhydramine 2
tryptophan 2
5-HT 2
Ach 2
aspartic acid 2
DSM 2
aspartic acid 2
hydrogen 2
TBE 2
iron 2
glucose 2
Optimal 2
zinc 2
DTPA 2
TSH 2
Hypaque 2
Spironolactone 1
Botulinum toxin type A 1
Mefloquine 1
EDTA 1
Thyroid 1
ANA 1
Dial 1
Verapamil 1
Austin 1
TNF 1
PPD 1
6-12 1
ethanol 1
acrylamide 1
DEP 1
DHC 1
GABA 1
Diltiazem 1
acetic acid 1
TAA 1
Diltiazem 1
Pyrazinamide 1
Lactulose 1
acetate 1
Salt 1
MMC 1
MIC 1
H2S 1
Vitamin D 1
GSH 1
Lactate 1
Cortisol 1
A 3 1
GDP 1
silver 1
DOS 1
phosphorus 1
UDP-galactose 1
Prednisone 1
A 1 1
THE 1
Sodium 1
Calcitonin 1
CAA 1
Polypeptide 1
tin 1
Glucagon 1
DNP 1
BMC 1
Hemoglobin 1
GSH 1
SEE 1
IAS 1
noradrenaline 1
Rifampicin 1
glutamic acid 1
Mefloquine 1
GTP 1
A 42 1
acetaldehyde 1
Isoproterenol 1
ASA 1
PAC 1
ANA 1
nicotinamide 1
GABA 1
Dihydroergotamine 1
Naloxone 1
PPD 1
lysine 1
folinic acid 1
copper 1
gamma-aminobutyric acid 1
Omeprazole 1
glutamate 1
Pac 1
DEP 1
N-acetylaspartate 1
Bethanechol 1
aldehyde 1
Parenteral 1
Ferrous sulfate 1