Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0014848 (achalasia)
 2,804 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Diverticula of the oesophagus are a rare disease with an interesting patho-physiology which is the basis for a correct indication and surgical procedure. Our experience bases on 72 operated cases with a long follow-up. The pharyngo-oesophageal or Zenker's diverticulum and the epiphrenic diverticulum are pulsion diverticula above an achalasic sphincter: the upper cervical and the LES. A surgical treatment is necessary in the most cases of Zenker's, in the epiphrenic form depending on symptoms and risk. The treatment of Zenker's is a cervicotomy with diverticulectomy (we use a stapler) and accurate myotomy of the cricopharyngeus. A beginning little D or a cervical achalasia without D are often the cause of serious and lasting symptoms. Here the alone cricomyotomy is the procedure of choice. Reflux disease is frequently associated with Zenker's, sometimes a surgical problem too. The operation of the epiphrenic D is a left thoracotomy with diverticulectomy and the very important abolition of the causal achalasia with myotomy and antireflux (by us a fundoplication). The traction diverticula of the thoracic oesophagus are frequently asymptomatic. Operation with right thoracotomy is exceptionally necessary on painful segmental dyskinesia of bezoar. It is essential on oesophago-respiratory fistula.
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PMID:[Surgical indication and technique in diverticulosis of the esophagus]. 184 11

Esophageal bezoars are rare, but are recognized as a distinct clinical entity. They are known to occur in patients with esophageal structural and functional abnormalities, but only a few cases of the development of esophageal bezoars in patients with esophageal motility disorders have only been described. We report a rare case of an esophageal bezoar that developed in a patient with achalasia, and review the literature concerning esophageal bezoars associated with esophageal motility disorders.
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PMID:Esophageal bezoar in a patient with achalasia: case report and literature review. 2047 21

A few cases with esophageal bezoar have been reported in achalasia. We describe here a rare case of esophageal pharmacobezoar after ingestion of ferrous sulfate capsules in a patient with achalasia. A 29-year-old woman presented with severe dysphagia since five days earlier. She had history of achalasia since 3 years ago but had refused any treatment option. After about 3 weeks of ferrous sulfate capsules ingestion, she developed severe dysphagia and was referred to a gastroenterologist. Physical examination was unremarkable. A barium swallow revealed dilated esophagus and bird's beak appearance. Esophagogastroduodenoscopy (EGD) showed dilated esophagus and soft black color bezoar in distal part of esophagus. The bezoar was retrieved with basket. In the next endoscopic session, achalasia balloon dilation was successfully applied. Ferrous sulfate capsules can cause pharmacobezoar in patients with achalasia. Esophageal bezoar should be considered in differential diagnosis of untreated achalasia and acute exacerbation of dysphagia.
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PMID:Esophageal Pharmacobezoar in a Patient with Achalasia: A Case Report. 3168 17