Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0014848 (achalasia)
 2,804 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 61-year-old male was evaluated for dysphagia. Esophageal manometry revealed vigorous achalasia. Upper-gastrointestinal endoscopy revealed a probable gastric neoplasm which was confirmed at laparotomy. Histologically the tumor was a lymphoma. Antineoplastic therapy resuted in rapid and complete improvement in the patient's dysphagia. Repeat esophageal manometry was normal. It is concluded that: (1) patients presenting with achalasia or vigorous achalasia should be carefully evaluated for the presence of a gastric malignancy involving the gastric fundus and lower esophagus; (2) chemotherapy may produce a resolution of esophageal symptoms.
 ...
PMID:Successful treatment of vigorous achalasia associated with gastric lymphoma. 738 32