Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0014547 (focal epilepsy)
 1,627 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
DEP domain-containing protein 5 13.6
DEP domain containing 5 13.3
DEPDC5 12.8
CPA6 12.7
SCNM1 12.3
TTC39C 11.9
KPTN 11.7
dystrobrevin alpha 11.7
XLIS 11.7
NPRL2 11.6
Proline-rich transmembrane protein 2 11.1
LGI2 10.8
KIAA1202 10.7
CHRNA2 10.6
potassium channel 1 10.3
ARHGEF9 10.3
LGI1 10.3
KCNT1 10.3
KCNAB1 10.3
TRIM3 10.3
ADLTE 10.2
HEPP 10.2
SLC6A13 10.1
SMEI 9.9
EMX2 9.8
FTSJ1 9.7
TBC1D24 9.6
SCN3A 9.6
CHRNB2 9.4
FLN 9.4
ADCY1 9.3
SLC35A2 9.3
CNTNAP2 9.3
TUBB1 9.2
SV2A 9.1
GPR56 9.1
Caspr2 9.0
ERC1 9.0
sox11 9.0
Glutamine:fructose-6-phosphate amidotransferase 9.0
GluR-C 8.9
TUBA1A 8.9
RELN 8.9
LIS1 8.8
SCN1A 8.8
CHRNA4 8.8
IGE 8.7
GABRA3 8.7
DLG4 8.7
CAMK2A 8.7
Cps1 8.7
betaine/GABA transporter 8.6
OTX1 8.5
GRIN2A 8.5
SCN8A 8.4
ADAM22 8.3
ARX 8.3
PQBP1 8.3
ADAM23 8.3
ARID5B 8.2
collybistin 8.2
GRM7 8.2
PCDH19 8.2
EEF1A2 8.0
DLG1 7.9
COL4A1 7.9
filamin A 7.8
NARP 7.8
CACNA1H 7.8
NMT 7.8
CACNA1G 7.7
Kv7.3 7.7
P58 7.7
erg3 7.7
VAMP1 7.7
AKT3 7.6
SLC2A1 7.5
PRRT2 7.5
Glutamate receptor 7.4
STXBP1 7.4
more...
Disease
focal epilepsy 14.3
Secondary generalized epilepsy 13.3
Childhood epilepsy with occipital paroxysms 13.3
Atypical benign partial epilepsy 12.4
Focal clonic seizures 12.4
Secondarily generalized seizures 12.4
partial monosomy Xq 12.3
XLIS 11.9
1q deletion syndrome 11.3
Musicogenic epilepsy 11.2
Frontal lobe epilepsy 10.9
Simple partial seizures 10.8
Rasmussen encephalitis 10.7
ADLTE 10.6
Microdysgenesis 10.6
Periventricular nodular heterotopia 10.5
GWC 10.4
Epileptic encephalopathy 9.9
IGE 9.8
hypsarhythmia 9.8
juvenile myoclonic epilepsy 9.7
Cortical dysplasia 9.5
TNDM 9.4
Landau-Kleffner syndrome 9.4
Generalized epilepsy 9.4
atonic seizure 9.3
triplegia 9.3
Feingold syndrome 9.3
Hopkins syndrome 9.2
Temporal lobe 9.2
temporal lobe epilepsy 9.1
pachygyria 9.1
schizencephaly 9.1
tonic-clonic status epilepticus 8.9
WTS 8.9
Lennox syndrome 8.9
Phosphenes 8.8
Axis II diagnosis 8.8
Lennox-Gastaut syndrome 8.8
Sandifer syndrome 8.7
Recurrent seizures 8.7
Limbic encephalitis 8.6
Lennox-Gastaut syndrome 8.5
Epilepsia partialis continua 8.4
Ohtahara syndrome 8.4
petit mal 8.4
epilepsy 8.4
GEFS+ 8.4
grand mal epilepsy 8.4
psychomotor epilepsy 8.3
complex partial seizures 8.2
audiogenic epilepsy 8.2
XYY syndrome 8.1
Central sleep apnea 8.0
LIS1 8.0
Tuberculomas 7.8
SUDEP 7.8
reflex epilepsy 7.8
lissencephaly 7.7
generalized seizure 7.7
18q- syndrome 7.7
GIN 7.7
hypomenorrhea 7.6
Sweeney 7.6
Axis I diagnosis 7.5
ganglioglioma 7.4
Hippocampal sclerosis 7.4
febrile convulsions 7.3
status epilepticus 7.1
PRS 7.1
acalculia 7.1
choreoathetosis 7.1
exhibitionism 7.0
sleepwalking 6.8
coproporphyria 6.8
Wernicke's aphasia 6.7
Dubowitz 6.7
Fahr's disease 6.7
Drechslera 6.7
pansinusitis 6.6
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Symptom
Postictal headache 11.9
Hyposexuality 11.4
Visual phenomena 10.8
Todd's paralysis 8.9
partial seizure 8.4
Circling 8.3
seizures 7.9
Hyperekplexia 7.9
Hemicrania 7.8
bigeminal 7.3
tonic-clonic seizure 7.1
startle reaction 7.0
Neurologic symptoms 6.7
clonus 6.7
tonic seizure 6.5
disturbed balance 6.4
tingling 6.3
auditory hallucination 6.2
visual hallucination 6.1
myoclonus 5.7
belching 5.6
hemiplegia 5.5
clumsiness 5.2
sleepiness 5.1
personality change 5.1
abnormal gait 5.1
excessive sweating 5.1
dizziness 5.0
drooling 4.9
hypotonia 4.5
twitching 4.3
blurred vision 4.2
hypersomnia 4.2
nasal congestion 4.1
syncope 4.1
decreased appetite 4.1
facial pain 4.1
dysarthria 4.0
asthenia 3.9
hoarseness 3.7
enuresis 3.6
paresthesia 3.6
dystonia 3.5
alexithymia 3.5
numbness 3.5
cerebellar ataxia 3.4
memory loss 3.4
tremor 3.4
headache 3.2
chorea 3.2
ataxia 3.1
vertigo 3.0
vomiting 2.9
paraparesis 2.8
sore throat 2.8
lethargy 2.8
spasticity 2.6
spasm 2.4
hypercapnia 2.3
cough 2.3
insomnia 1.9
thinning 1.8
fatigue 1.8
hepatomegaly 1.8
paresis 1.7
agitation 1.7
weakness 1.6
anorexia 1.5
discomfort 1.4
nausea 1.3
discomfort 1.3
abdominal pain 0.9
angina 0.9
Ill 0.8
back pain 0.7
anesthesia 0.7
erythema 0.6
pain 0.4
collapse -0.5
diarrhea -1.6
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Drug
Klonopin 11.1
Cloxazolam 11.1
Felbatol 11.1
Gabitril 10.4
Gabitril 10.2
Zonegran 10.1
Sulthiame 10.0
Topamax 9.3
Stiripentol 8.5
Oxaprozin 8.3
Keppra 8.2
Methohexitone 8.1
GVG 7.9
Valproic Acid 7.7
Zonisamide 7.7
Pregabalin 6.5
Phenytoin 6.5
Gabapentin 6.0
Sodium valproate 5.9
AIC 5.2
EPI 5.2
CPM 5.0
Kainic acid 4.9
9-THC 4.5
GRF 4.3
DPA 3.9
FeCl3 3.8
Frontal 3.2
Propofol 3.2
NAG 3.2
MDS 3.1
TMS 3.1
L-tyrosine 3.0
HCG 2.9
ICI 2.9
ROC 1.3
EE2 1.3
MAP 1.3
THF 1.3
ENT 1.2
CTX 0.9
NADH 0.8
CSF 0.3
Monit -0.8
Enzyme
NMT 7.9
tetanus neurotoxin 7.6
adenosine kinase 6.0
PME 5.7
CPM 4.9
Alternating 4.6
TSP-1 4.5
FFT 4.5
BIS 4.4
glutamate decarboxylase 4.2
ADH 3.1
glutamine synthetase 3.0
granzyme B 2.6
carbonic anhydrase 2.4
glutamate dehydrogenase 2.2
glutamate dehydrogenase 2.2
caspase-8 1.5
MAP 1.4
succinate dehydrogenase 1.3
complex I 1.1
gamma-glutamyl transpeptidase 1.1
alcohol dehydrogenase 1.1
creatine kinase 1.0
P-glycoprotein 0.6
acetylcholinesterase 0.5
tyrosine hydroxylase 0.4
ATPase -0.2
peroxidase -0.2
catalase -0.5
lactate dehydrogenase -0.6
protein kinase -1.1
trypsin -1.1
mitogen-activated protein kinase -1.3
alkaline phosphatase -1.3
ERK -2.3
Compound
Trimethadione 9.0
Levetiracetam 8.9
Homotaurine 8.8
IGE 8.7
Zonisamide 8.6
CZP 8.5
Oxcarbazepine 8.2
Amytal 8.2
Clobazam 8.1
Lamotrigine 8.0
Tiagabine 7.9
Ethosuximide 7.9
Vigabatrin 7.8
Topiramate 7.0
DEP 7.0
IEA 6.8
P 2 6.7
DEP 6.6
Clonazepam 6.5
methanesulfonamide 6.3
methanesulfonamide 6.3
Flumazenil 6.3
Thiopental 6.0
TBC 5.6
DPH 5.6
Penicillin 5.5
Corticotropin 5.5
Penicillin 5.5
Valproic acid 5.2
Tetraethylammonium 5.2
GAP 5.2
HOG 5.2
Tetrahydrocannabinol 5.1
Valproic acid 5.1
STP 5.0
TSC 4.9
Kainic acid 4.9
Kainic acid 4.9
Bicuculline 4.9
Neurotol 4.9
GABA 4.6
GABA 4.6
Hypo 4.3
Xenon 4.2
gamma-aminobutyric acid 4.2
4-AP 4.1
DAG 4.1
5-methylisoxazole 4.1
DMD 4.1
Midazolam 4.0
LTD 4.0
MES 3.9
MES 3.9
triphenylphosphine 3.9
MPA 3.9
MPA 3.8
Austin 3.8
Argentine 3.8
MPA 3.8
naphthoquinone 3.7
AICAR 3.7
IMP 3.6
Neuronal 3.6
N-acetylaspartate 3.6
Carbachol 3.4
SPM 3.3
AMPA 3.3
Methionine 3.3
aminomethyl 3.2
cobalt 3.2
Propofol 3.1
coenzyme Q10 3.0
SEE 3.0
isoxazole 2.9
Cereb 2.8
ACTH 2.8
glutamate 2.7
propionic acid 2.6
propionic acid 2.6
Guo 2.6
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