Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
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Query: UMLS:C0014547 (
focal epilepsy
)
1,627
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We describe a patient with the coincidence of 2 ion channel disorders with autosomal dominant inheritance:
Brugada syndrome
, a potentially fatal cardiac condition, and cryptogenic
focal epilepsy
, likely due to a neurologic channelopathy. Although
Brugada syndrome
was discovered incidentally, most of the clinical features of epilepsy in this patient shared the risk factor characteristics of sudden unexplained death in epilepsy syndrome. This case provides additional information on the potential interaction between ion channel abnormalities in the heart and in the brain. Furthermore, it may suggest that patients with epilepsy at increased risk for sudden unexplained death in epilepsy syndrome should undergo a careful cardiac evaluation.
...
PMID:Electrical storm in the brain and in the heart: epilepsy and Brugada syndrome. 2407 86
