Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0014544 (epilepsy)
64,704 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 4064
MRI 2385
GABA 1786
Mol 1276
CA1 1037
CA3 727
She 588
SCN1A 449
NMDA receptor 415
axonal 360
sodium channel 344
X-linked 328
Pol 327
mTOR 308
insulin 287
glial fibrillary acidic protein 283
ATP 274
GABA(A) receptor 273
CSF 266
glutamate receptor 228
P-glycoprotein 215
parvalbumin 214
calcium channel 212
brain-derived neurotrophic factor 204
KCNQ2 204
ionotropic 199
AED 192
cytokine 189
Rett syndrome 188
olfactory 179
voltage-gated sodium channel 175
REM 175
FDG 167
TSC2 157
HBA 151
TSC1 150
somatostatin 144
glutamic acid decarboxylase 142
endoplasmic reticulum 136
MEG 133
superoxide dismutase 131
amyloid precursor protein 127
caspase-3 126
DBA 123
TNF 122
neuropeptide Y 122
ATPase 118
por 117
IL-6 117
prolactin 115
cytochrome P450 113
ACTH 107
DCX 105
KCNQ3 103
nicotinic acetylcholine receptor 101
KCC2 100
histone 100
beta-endorphin 100
tRNA 99
GSH 98
carbonic anhydrase 96
GABA transporter 95
catalase 94
tumor necrosis factor 94
nitric oxide synthase 92
CDKL5 89
LGI1 88
albumin 88
glutamate transporter 87
asymmetrical 87
Gen 86
glucose transporter 82
CA2 82
ICD 81
c-fos 81
ANOVA 79
calbindin 79
metabotropic glutamate receptor 78
voltage-gated potassium channel 78
ACS 78
more...
Disease
epilepsy 64704
temporal lobe epilepsy 3630
status epilepticus 3154
depression 2332
fits 1913
stroke 1864
mental retardation 1534
mental retardation 1529
encephalopathy 1455
autism 1391
Alzheimer's disease 1383
schizophrenia 1179
focal epilepsy 1107
migraine 1058
cognitive impairment 1027
dysplasia 1026
developmental delay 1013
tumor 1003
Parkinson's disease 985
complex partial seizures 926
dementia 840
psychosis 799
tuberous sclerosis 741
encephalitis 723
cancer 682
multiple sclerosis 669
neurological disease 654
diabetes 644
cerebral palsy 614
West 598
Lennox-Gastaut syndrome 583
ischemia 536
juvenile myoclonic epilepsy 520
febrile convulsions 517
hypertension 501
Lennox-Gastaut syndrome 464
petit mal 405
hydrocephalus 383
mental illness 381
bipolar disorder 362
glioma 346
confusion 334
hemiparesis 332
coma 314
obesity 308
asthma 293
sleep disorders 289
Huntington's disease 285
generalized seizure 281
brain tumor 275
aphasia 268
hallucinations 268
aggression 257
memory impairment 257
amyotrophic lateral sclerosis 254
brain atrophy 231
anxiety disorders 228
meningitis 224
Rett syndrome 223
chronic pain 222
lissencephaly 218
ADHD 216
major depressive disorder 216
deafness 206
hypoglycemia 202
Syndrome 201
Autism 198
cerebral ischemia 197
myoclonus epilepsy 190
amnesia 188
photosensitivity 187
severe mental retardation 185
Down syndrome 185
cysticercosis 184
rash 183
alcoholism 183
genetic disorder 175
brain dysfunction 174
hamartoma 169
Landau-Kleffner syndrome 167
more...
Symptom
seizures 29183
pain 1156
headache 986
ataxia 920
myoclonus 683
sleepiness 529
anesthesia 457
tremor 436
hypotonia 396
tonic-clonic seizure 372
partial seizure 355
syncope 348
dystonia 338
stigma 306
dizziness 303
vomiting 280
hemiplegia 268
fatigue 261
weakness 258
spasticity 233
insomnia 217
cerebellar ataxia 217
nausea 151
clonus 135
agitation 134
vertigo 115
spasm 113
lethargy 105
diarrhea 102
dysarthria 98
cough 96
paresis 90
chorea 89
memory loss 84
anorexia 82
hypothermia 82
abdominal pain 80
ophthalmoplegia 78
analgesia 71
twitching 69
discomfort 69
tonic seizure 68
discomfort 66
collapse 62
tinnitus 59
functional recovery 57
paresthesia 50
constipation 49
asthenia 48
thinning 46
respiratory distress 45
nausea and vomiting 43
overweight 40
dyspnea 40
enuresis 39
hypertonia 37
hoarseness 36
cyanosis 35
neuralgia 33
drooling 30
athetosis 28
starvation 28
paraparesis 28
angina 27
catatonia 26
apathy 26
incoordination 24
back pain 24
personality change 24
consciousness disturbance 24
livedo 23
blurred vision 23
chest pain 23
exhaustion 22
acute stress 21
pallor 21
clumsiness 21
neurological disability 21
eds 20
numbness 20
more...
Drug
CSF 268
Phenytoin 202
Gabapentin 142
Monit 114
lysine 94
Zonisamide 90
Sodium valproate 84
Vitamin B 83
Pilocarpine 71
Dermatol 67
Pregabalin 63
caffeine 60
MAP 59
Kainic acid 48
pyridoxal phosphate 45
vitamin E 42
DPA 41
DBS 40
Spectrum 39
GVG 38
Spectrum 37
Frontal 36
ABC 33
Propofol 30
Rufinamide 29
Keppra 28
ascorbate 27
Stiripentol 26
ROS 25
Cardiovasc 23
NADH 23
Histamine 22
ROC 22
Leaf 20
EPI 19
TMS 19
Nephron 18
IL-2 17
PCP 17
Portal 17
Ethanol 17
ampicillin 16
CTX 16
9-THC 16
EE2 16
FeCl3 15
Topamax 14
Fosphenytoin 14
Dakar 14
Remacemide hydrochloride 13
Everolimus 12
Ganaxolone 11
Valproic Acid 11
citric acid 11
Glutathione 11
CTX 11
Sulthiame 11
p75 11
CTX 11
Zonegran 10
Albumin 10
Atropine 10
Estrogens 10
Clonidine 9
LCM 9
LCM 9
Asthma 9
Vitamin E 9
Piracetam 9
Zmax 9
ENT 9
Dilantin 9
Azithromycin 9
Finasteride 9
Flurothyl 8
Kenyan 8
Agomelatine 8
Norplant 8
Progabide 8
Bumetanide 8
more...
Enzyme
P-glycoprotein 216
mitogen-activated protein kinase 167
superoxide dismutase 151
protein kinase 142
catalase 128
ATPase 126
carbonic anhydrase 109
ERK 106
acetylcholinesterase 101
caspase-3 100
ACS 78
protein kinase C 75
GABA transaminase 73
alkaline phosphatase 72
glutathione peroxidase 58
complex I 57
glutamine synthetase 57
glutamate decarboxylase 56
calcineurin 52
adenosine kinase 47
monoamine oxidase 45
peroxidase 44
luciferase 43
CaMKII 41
tyrosine hydroxylase 40
alanine aminotransferase 39
pyruvate dehydrogenase 38
aspartate aminotransferase 38
CYP3A4 38
cytochrome oxidase 38
NO synthase 38
creatine kinase 37
cholinesterase 36
PHT 35
proteasome 35
pyruvate dehydrogenase 30
focal adhesion kinase 30
pyruvate dehydrogenase 30
lactate dehydrogenase 29
reverse transcriptase 28
phospholipase C 28
NOS 27
succinate dehydrogenase 26
renin 25
tissue plasminogen activator 23
PME 23
phosphatidylinositol 3-kinase 22
adenosine deaminase 21
CPS 21
GSK 21
adenosine deaminase 21
succinic semialdehyde dehydrogenase 21
choline acetyltransferase 21
phosphoinositide 3-kinase 20
phosphodiesterase 19
glutamate dehydrogenase 18
thrombin 18
glutathione reductase 18
PCP 17
MEK 17
MDR 17
gamma-glutamyl transpeptidase 17
AMPK 16
neuraminidase 16
glutathione S-transferase 16
glutamate dehydrogenase 16
DNA polymerase 16
glutamate dehydrogenase 16
guanidinoacetate methyltransferase 15
AMP-activated protein kinase 14
methylenetetrahydrofolate reductase 14
phospholipase A2 14
methylenetetrahydrofolate reductase 14
ATP synthase 14
ceruloplasmin 14
beta-galactosidase 13
NADPH-diaphorase 12
adenylosuccinate lyase 12
glyceraldehyde-3-phosphate dehydrogenase 12
enolase 12
more...
Compound
Dec 4483
Clin 3402
GABA 1836
GABA 1808
glutamate 1671
sodium 1542
calcium 1299
DNA 852
potassium 801
glucose 759
water 688
gamma-aminobutyric acid 635
Valproic acid 561
oxygen 520
NMDA 462
His 407
AMPA 353
Neurotol 326
Neuronal 316
Cardiol 301
ATP 274
Lamotrigine 262
Valproic acid 262
Levetiracetam 250
DPH 246
phosphate 207
nitric oxide 193
5-HT 190
arginine 189
Glutamate 175
Cereb 175
zinc 174
Topiramate 167
acetate 158
Vigabatrin 154
glutamine 153
lysine 152
iron 147
leucine 144
ethanol 136
serine 134
Luminal 125
DBA 123
DSM 123
DBA 123
DBA 123
TNF 122
ACTH 119
Mg2+ 116
fluorine 115
tryptophan 114
bromide 111
hydrogen 109
vitamin D 107
GSH 106
GSH 106
tryptophan 105
tryptophan 103
tryptophan 103
noradrenaline 100
Adenosine 95
tyrosine 92
Zonisamide 90
Diazepam 89
ammonia 88
cobalt 85
galactose 85
homocysteine 84
alanine 83
Oxcarbazepine 81
methionine 80
vinyl 80
sulfate 79
ACS 79
ACS 78
creatinine 78
cAMP 77
cysteine 73
Pilocarpine 71
butyric acid 70
more...