Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

1013 patients with cardiac valve replacement during a 12-year period from 1978 to 1990 were reported. 566 cases were implanted with Shanghai-made tilting disc valve prostheses and 447 with Lanzhou-made (C-L valves). Mitral valve replacement (MVR) in 753 patients, aortic valve replacement (AVR) in 102 and double valves replacement (DVR) in 158. The overall early mortality rate was 6.2% with 4.9%, 7.8% and 11.3% after MVR, AVR and DVR respectively. Follow-up study was made in 3097.43 patient-year (mean 3.26 years). The late death rate was 1.6% patient-years and with 1.4, 1.8 and 3.2 after MVR, AVR and DVR respectively. The incidence of late valve-related complication (% patient-years) were: thromboembolism 0.39, anticoagulant-related hemorrhages 0.77, prostheses failure 0.22, prosthetic valve endocarditis 0.38, periprosthetic leak 0.12, and reoperations 0.38. The domestic tilting disc valve prostheses are considered to be qualified valves with low mortality and satisfactory results.
Zhonghua Xin Xue Guan Bing Za Zhi 1992 Feb
PMID:[A 12-year clinical experience of cardiac valve replacement with domestic tilting disc valve prostheses in 1013 cases]. 139 87

To assess the value of intraoperative transesophageal echocardiographical Doppler color flow imaging (TEE-DCFI) during cardiac valvular surgery, 85 consecutive patients with 102 diseased valves for surgery were studied with pre-and post-operative TEE-DCFI. There were 34 women and 51 men with an age range of 15 to 55 years (mean age, 34.91 +/- 9.33 years). The etiology of valve lesion was rheumatic in 57 (AV 10, MV 47), prolapse in 9 (AV 2, MV 7), endocarditis in 21 (AV 12, MV 3, PV 2, prosthetic infection 4), prosthetic dysfunction in 14 (AV 5, MV 9), congenital in 1 (TV). Preoperative TEE-DCFI findings were helpful either in completing with some new information or changing the operation plan in 29 valves (28.43%) including abscess at aortic root in 1, perforation of aortic valve in 2, perforation of mitral valve leaflets in 5 patients with aortic valvular endocarditis, regurgitation or perivalvular leak of prosthetic valve in 4 MVs and 4AVs, left atrial thrombus detected in 8 and excluded in 3 patients with MV disease, small calcified vegetation on PV with normal valve function in 2 patients with congenital heart disease. Postoperative TEE-DCFI evaluation was performed in 53 patients with 70 diseased valves. There was only one mild regurgitation of mitral bioprosthesis and one mild perivalvular leak of aortic prosthesis detected among 40 replaced prosthetic valves. Of 30 valves repaired 23 (77%) valves had trivial or mild residual regurgitation (Group A) and 7 (23%) had moderate residual regurgitation (Group B). Postoperative congestive heart failure was seen in 6 (26.09%) of Group A and 5 (71.43%) of Group B (P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
Zhonghua Xin Xue Guan Bing Za Zhi 1990 Aug
PMID:[The value of using transesophageal echocardiographic Doppler color flow imaging in patients undergoing cardiac valvular surgery]. 208 76

Between January, 1976 and April 1988, 1279 patients underwent open-heart operation in Ren Ji Hospital. Thirty three patients were complicated by infective endocarditis postoperatively, an incidence of 2.58%. Medical treatment was carried out in 29 cases and thirteen were cured. In another three patients of valve prosthetic endocarditis, replacement of prosthetic valve was necessary for their cure. In our series, Gram negative bacilli had been proved by blood culture, autopsy and arterial thrombi in thirteen patients and candida in four, mixed infection in five and staphylococcus aureus in only one case. One should not rely on positive blood culture for the diagnosis. Echocardiographic studies are helpful to early diagnosis and proper treatment. The presence of vegetation or signs of prosthetic valve failure are strong indication for reoperation. In prevention, in addition to strict aseptic technic in the operating room, special emphasis should be focused on the preventive administration of sensitive antibiotics against hospital borne pathogens. All indwelling catheters in arteries and veins, tracheal tubes and urethral catheters should be removed after 72 hours. Efforts to prevent infection after reoperation are important measures for the prevention of infective endocarditis after open-heart operation.
Zhonghua Xin Xue Guan Bing Za Zhi 1989 Aug
PMID:[Endocarditis after extracorporeal circulation surgery]. 262 71

One hundred patients with patent ductus arterious (PDA) were treated successfully by percutaneous transfemoral plug closure since 1985. Age ranged from 5 to 48 years. Among them five had previous ligation of PDA, One was complicated with infective endocarditis, and in four pulmonary hypertension were found. The internal diameter shown in aortograph ranged from 0.26-1.0 cm. Primary success was accomplished after the first trial in 97 patients and second trial was necessary in three cases. However in one patient plug closure was given up after unsuccessful trial. The plug closure was carried out with domestic-made material and instrument in all cases. We adopted the modified Porstmann technique. We believe that the infrainguinal transfemoral approach is simple, and less traumatic. The indication of plug closure can be extended especially to residual or recanalization cases after ligation in selected cases. It may become the method of first choice for PDA. The "papillary type" of PDA is discussed and a specially designed and tailored plug and also a spontaneous flow-directed method were recommended. Frequent ventricular premature beats usually occurred while the catheters were being pushed through chordae tendinae of the tricuspid valve and the way of prevention was discussed. In case of dislodgement of plug, reestablishing the wire locus would be necessary. One to sixty-eight months follow up study after closure showed no sign of recanalization or residual shunt.
Zhonghua Xin Xue Guan Bing Za Zhi 1993 Jun
PMID:[Percutaneous transfemoral plug closure of patent ductus arteriosus in 100 cases]. 824 30