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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Tissue samples taken during a surgical procedure performed for therapeutic reasons in 27 patients with acquired valvular heart disease (a.v.h.d.) were subjected to histopathological examinations. The aim of the work was to carry out simultaneous studies of several organs in the same patients. The samples were taken from: left heart auricle (15 cases), heart valves (15 cases), palatine tonsils (10 cases), subcutaneous tissue (14 cases) and periodontium (9 cases). Out of the total number of 27 cases samples from 5 organs of the same person were examined once, from 4 organs twice, from 3 organs twelve times, and from 2 organs fifteen times. In 90% of cases marked qualitative and quantitative compatibility between histopathological pictures of connective tissue changes was found. These changes consisted in an increased number of collagen fibres and hyalization of connective tissue. The authors conclude that infective endocarditis could be in connection of a primary general collagenopathy.
Mater Med Pol
PMID:Histopathological studies of connective tissue in patients with acquired valvular heart disease. 248 42

Echocardiography, both transthoracic and transesophageal techniques, is the procedure of choice in the diagnosis and management of patients with endocarditis. First of all, vegetative lesions can be detected. Echocardiography also plays a major role in recognition of such complications of endocarditis as: perivalvular abscesses, aneurysms, fistulas, rupture of valvular leaflets, chordae and papillary muscles or the interventricular septum. It provides useful information on valve destruction, severity of insufficiency, prosthetic valve dysfunction and, finally, it provides a chance for optimal medical and surgical therapy.
Pediatr Pol 1995 Aug
PMID:[Use of echocardiographic examination for infective endocarditis]. 866 70

4 endocarditis lenta cases with negative blood cultures are reported: 3 patients with risk heart lesions and 1 subject with no predisposing cardiac condition. The mean age of the patients was 53.7 years. Based on the cases reported the following items are discussed: evolution of the clinical syndrome, diagnostic difficulties, problem of negative blood cultures, therapeutic procedure.
Pol Arch Med Wewn 1996 Jan
PMID:[Endocarditis lenta--a problematic disease]. 867 96

A case of pneumonia associated with pneumococcal endocarditis of bicuspid aortic valve complicated by pneumococcal meningitis and panophthalmitis successfully treated by antibiotics and late valve replacement was described.
Pneumonol Alergol Pol 1998
PMID:[Pneumonia and panophthalmitis as first signs of pneumococcal endocarditis]. 985 55

Endocarditis is an infectious and inflammatory disease of cardiac valves with other coexisting symptoms affecting heart and other organs and systems. Patients with cardiac valves diseases are in the group of high risk. The authors present a case of successfully treated endocarditis affecting mitral valve prosthesis in the course of staphylococcus septicaemia complicated by intracranial haematoma.
Neurol Neurochir Pol
PMID:[A rare case of intracranial hematoma complicating bacterial endocarditis]. 1054 Jul 30

The infective endocarditis is a septic syndrome caused by an infection in endocardium or in heart valves. The majority of patients with infective endocarditis develop normocytic anemia. The metabolic studies in septic shock syndromes documented an intensive proteolysis of muscles, visceral organs and blood proteins, and probably of erythropoietin as a glycoprotein as well. The aim of the study was to assess the erythropoietin level in patients with infective endocarditis severe anemia and preserved renal function. Erythropoietin concentration was measured in blood serum in 12 patients (11 men and 1 woman), mean age 48 +/- 8 years, with infective endocarditis. The patients had clinical symptoms of endocarditis, positive blood bacteriological cultures and echocardiography features. All patients had serious normocytic anemia with mean hemoglobin concentration 5.40 +/- 0.48 mmol/L. The control group consisted of 7 healthy persons (5 men and 2 women), mean age 50 +/- 7 years, with hemoglobin concentration 8.70 +/- 0.60 mmol/L. The concentration of erythropoietin at the patients with bacterial endocarditis was 144.04 +/- 17.80 mIU/mL versus 67.28 +/- 6.29 mIU/mL in the control group (p = 0.0002). We conclude that in patients with infective endocarditis and serious normocytic anemia without renal insufficiency the concentration of erythropoietin is increased.
Pol Arch Med Wewn 1999 Feb
PMID:[The level of erythropoietin in serum of patients with anemia during infective endocarditis]. 1072 24

In the most patients the mitral valve prolapse (MVP) syndrome has a good prognosis. The gradual progression of MR may cause the progressive LV dysfunction and development of heart failure. Long-term prognostic studies showed, that complications like endocarditis, cerebrovascular accidents occur frequently in pts. with mitral systolic murmur, thickened mitral valve leaflets and presence of MR. The diagnosis of MVP is made by cardiac auscultation and confirmed by echocardiography. The procedures usefulness in sudden death stratification are discussed. The management of the symptomatic patients, particularly the indication for prophylaxis of endocarditis and cerebrovascular accidents has been demonstrated. The indications for cardiac catheterisation and surgical treatment are presented.
Pol Merkur Lekarski 2000 Aug
PMID:[Mitral valve prolapse--diagnostic and therapeutic implications]. 1108 30

We report an analysis of clinical course of 18 patients presenting with Staphylococcus aureus sepsis. Community acquired infection was caused by Methicillin susceptible S. aureus (MSSA) in 11 patients. MSSA in 3 and Methicillin Resistant S. aureus strains (MRSA) in 4 patients, were the etiologic factor in 7 patients with nosocomial infection. From anamnestic data patients presented with: elevated body temperature--18/18, arthralgia and myalgia--9/18, headache--8/18, nausea--6/18, chills--2/18. Physical examination on admission revealed: meningismus--12/18, hepatomegaly--11/18, purulent and haemorrhagic skin lesions--7/18 and impaired neurological status (Glasgow Coma Scale < or = 12)--6/18. The mean APACHE III score, calculated from data collected at diagnosis of sepsis was 47 (7-114). Several complications had been observed: endocarditis--10, purulent meningitis--5, focal CNS lesions--5, pneumonia--8, pulmonary abscess--3, hydrothorax--1, abscesses of the spleen--5, renum--4, osteomyelitis--2. 11/18 patients required ICU treatment. Ventilator assistance of respiration was necessary in 7/18. Acute thrombocytopenia (< 100,000/ml) was diagnosed in 60%. In 5 patients suppurative meningitis had been diagnosed with a mean pleocytosis-837 (173-1898) microL. The results of treatment were satisfactory in 11 patients, 3 patients required further surgical treatment (2--cardiosurgery, 1--orthopedic surgery), 4 patients died. Infection caused by community acquired MSSA strains had been characterized by severe clinical course with increased incidence of endocarditis, organ failure and abscess forming. We conclude that Staphylococcus aureus sepsis is still a life-threatening disease, which should be treated at centers with immediate access to imaging techniques of CNS and circulatory system as well as intensive care and cardiosurgery. Community acquired S. aureus sepsis compared with nosocomial infection is characterized by more severe clinical course and higher mortality, despite of a great susceptibility to most antibiotics of causative S. aureus strains.
Pol Merkur Lekarski 2001 Oct
PMID:[Staphylococcus aureus sepsis--still life threatening disease]. 1177 Mar 18

Cardiac abnormalities has been receiving increased attention in patients with systemic lupus erythematosus (SLE). Cardiovascular system involvement has been found to have a substantial effect on mortality and morbidity in patients with SLE [1]. Recent diagnostic methods using echocardiography examination have allowed the delineation of cardiac manifestations such as myocarditis and myocardial dysfunction, valvular disease, pericardial disease or pulmonary hypertension. A report of two cases is presented: 23-year-old man with acute myocarditis with left ventricular failure and pulmonary oedema as a initial presentation of active SLE, and 51-year-old woman with SLE, antiphospholipid antibodies, with history of cerebral embolic infarction, TIA and venous thrombosis and with mitral valvular dysfunction in course of nonbacterial thrombotic endocarditis. Pulmonary hypertension has been recognised in both patients probably as a result of vasculaopathy and intimal proliferation, vasculitis, thromboembolic disease or parenchymal lung disease in SLE. Recent advances in diagnosis and treatment have substantially improved the prognosis of patients with systemic lupus erythematosus and cardiovascular system involvement [2].
Pol Arch Med Wewn 2003 Feb
PMID:[Cardiovascular involvement in systemic lupus erythematosus: report of two cases]. 1287 81

Acute, febrile disease in a young person with no previous medical history is most often caused by infection. If disease progresses despite antimicrobial treatment vascular and collagen diseases should be taken into account in differential diagnosis We present a case of a young man, with lung infiltrations and cavities in the course of febrile illness. He was referred to our hospital with a suspicion of Wegener's granulomatosis after few days of ineffective antimicrobial therapy. Positive blood culture for S. aureus and demonstration of tricuspid valve vegetation on echocardiographic examination enabled to make a final diagnosis of infective endocarditis with multiple lung abscessus.
Pneumonol Alergol Pol 2003
PMID:[Sepsis with staphylococcal vegetation on tricuspid valve. Differential diagnosis with Wegener's granulomatosis]. 1458 33


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