Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The objective of this study was to determine the outcome of neglected minimal or moderate aortic regurgitation during mitral or mitro-tricuspid valve surgery. 42 patients were included in this survey between 1985 and 2002. There were 17 men and 25 women aged 9-54 years (mean age: 22 +/- 10 years). Etiology was dominated by acute rheumatic fever (91%). Associated lesions were observed: mitral valve incompetence 11 cases, mitral valve stenosis 9 cases, mitral valve incompetence plus mitral valve stenosis in 8 pateints and mitro-tricuspid valve disease in 14 others. All the patients were symptomatic (NYHA class II 79%, NYHA class III or IV 20%). 90% of patients had a radiological cardiomegaly: mean cardio-thoracic was 0.62. At electrocardiogram, 79% of patients were in sinus rhythm and 57% presented a left ventricular hypertrophy. Minimal or moderate aortic regurgitation has been confirmed by echocardiography and angiocardiography in all patients. Surgical treatment was a mitral valve replacement (n = 35.83%), a mitral valvuloplasty (n = 5.12%), a mitral valve replacement and a tricuspid valve annuloplasty according to DE VEGA technique (n = 2.5%). The operative mortality was 4.7% (2 deaths) due to an acute cardiac failure (1 case) and prosthetic valve endocarditis (1 case). 19 patients have been followed up from a mean 1 month to13 years (mean follow-up: 5 years). The follow-up has been marked by a regression or a stability of the neglected aortic incompetence , a regression of the mean cardio-thoracic ratio from 0.62 preoperatively to 0.56 postoperatively, an improvement of the functional status (84% of cases). We conclude that the neglected aortic incompetence during mitral or mitro-tricuspid valve surgery do not tend to aggravate during follow-up.
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PMID:[Aortic failure neglected in surgery of mitral or mitro-tricuspid valve diseases]. 1943 61