Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0014118 (endocarditis)
15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

161 patients underwent an aortic valve replacement from 1966 till January 1995 for active infective endocarditIS of the native aortic valve. The disease extended to the other cardiac valves in 39 patients and to the surrounding areas in 42 (aortic root and subaortic myocardial tissues). Indications for surgery were: congestive heart failure in 123, uncontrolled sepsis in 44 and emboli in 24. Total follow-up was 1,120 patient-years with a maximum follow-up of 29 years. Early mortality was 8%; late mortality was 3.6%/patient-year; recurrence rate of endocarditis was 1.3%/patient year; survival and reoperation free curve was 68% (S.E. +/- 0.04) at 10 years. These long term results are in favour of a surgical attitude with an acceptable surgical risk without delay.
Bull Mem Acad R Med Belg 1995
PMID:[The role of surgery in infectious endocarditis]. 884 90

Bartonellae are fastidious Gram-negative bacteria that are widespread in nature with several animal reservoirs (mainly cats, dogs, and rodents) and insect vectors (mainly fleas, sandflies, and human lice). Thirteen species or subspecies of Bartonella have been recognized as agents causing human disease, including B. bacilliformis, B. quintana, B. vinsonii berkhoffii, B. henselae, B. elizabethae, B. grahamii, B. washoensis, B. koehlerae, B. rocha-limaea, and B. tamiae. The clinical spectrum of infection includes lymphadenopathy, fever of unknown origin, endocarditis, neurological and ophthalmological syndromes, Carrion's disease, and others. This review provides updated information on clinical manifestations and seroepidemiological studies with an emphasis on data available from Brazil.
Mem Inst Oswaldo Cruz 2008 May
PMID:Human bartonellosis: seroepidemiological and clinical features with an emphasis on data from Brazil - a review. 1859 96

Candida albicans is the most common fungal pathogen known to cause endovascular infections, such as vascular catheter sepsis, infections of vascular prostheses and infective endocarditis. A C. albicans isolate was used to determine the apoptotic potential of the fungus in a rat endocarditis model. This study confirms the ability of C. albicans to induce apoptosis in myocardial tissue.
Mem Inst Oswaldo Cruz 2009 Sep
PMID:Candida albicans isolated from human fungaemia induces apoptosis in an experimental endocarditis model. 1987 56

Coxiella burnetii is the agent of Q fever , an emergent worldwide zoonosis of wide clinical spectrum. Although C. burnetii infection is typically associated with acute infection, atypical pneumonia and flu-like symptoms, endocarditis, osteoarticular manifestations and severe disease are possible, especially when the patient has a suppressed immune system; however, these severe complications are typically neglected. This study reports the sequencing of the repetitive element IS1111 of the transposase gene of C. burnetii from blood and bronchoalveolar lavage (BAL) samples from a patient with severe pneumonia following methotrexate therapy, resulting in the molecular diagnosis of Q fever in a patient who had been diagnosed with active seronegative polyarthritis two years earlier. To the best of our knowledge, this represents the first documented case of the isolation of C. burnetii DNA from a BAL sample.
Mem Inst Oswaldo Cruz 2012 Aug
PMID:Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene. 2285 Sep 65

We report the complete genome sequence and analysis of an invasive Corynebacterium diphtheriae strain that caused endocarditis in Rio de Janeiro, Brazil. It was selected for sequencing on the basis of the current relevance of nontoxigenic strains for public health. The genomic information was explored in the context of diversity, plasticity and genetic relatedness with other contemporary strains.
Mem Inst Oswaldo Cruz 2015 Sep
PMID:Genomic analysis of a nontoxigenic, invasive Corynebacterium diphtheriae strain from Brazil. 2651 65

Staphylococcus aureus subsp. aureus, commonly referred as S. aureus, is an important bacterial pathogen frequently involved in hospital- and community-acquired infections in humans, ranging from skin infections to more severe diseases such as pneumonia, bacteraemia, endocarditis, osteomyelitis, and disseminated infections. Here, we report the complete closed genome sequence of a community-acquired methicillin-resistant S. aureus strain, USA400-0051, which is a prototype of the USA400 clone.
Mem Inst Oswaldo Cruz 2017 Nov
PMID:Complete genome sequence of community-associated methicillin-resistant Staphylococcus aureus (strain USA400-0051), a prototype of the USA400 clone. 2909 Nov 41