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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A clinicopathological analysis of myocardial infarction with an onset of stroke-like symptoms was carried out on 30 autopsy cases at the Tokyo Metropolitan Geriatric Hospital. The cases were classified into four groups according to the types of brain lesions, I: embolism (n = 17), II: thrombosis (n = 9), III: bleeding (n = 2), and IV: no remarkable focal lesion (n = 2). Classification was made based on clinical findings, and pathological features. The characteristic clinical findings were conciousness disturbance, no elevation of blood pressure at the onset of stroke, hemiplegia and shock. However, the typical anginal chest pain was found in only 17% of cases. The underlying diseases and complications were hypertension, atrial fibrillation (Af), disseminated intravascular coagulation (DIC), renal failure, malignant neoplasma, and diabetes mellitus. The incidences of Af, DIC, mural thrombus, non-bacterial thrombotic endocarditis (NBTE) were significantly higher in the group with cerebral embolism than in the group with cerebral thrombosis. The coronary stenotic index was also smaller in the group with cerebral embolism. Therefore, the major etiology of cardio-cerebral apoplexy was a simultaneous embolism to the brain and heart due to Af, NBTE or, DIC.
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PMID:[Myocardial infarction beginning with cerebral symptoms in 30 cases of cardio-cerebral apoplexy]. 204 62

This work reports two cases of endocarditis caused by Actinobacillus actinomycetemcomitans. As noted in the medical literature, the mean clinical features are a subacute infection without know source of bacteremia, in a male patient aged 40 years or older and who is suffering from a heart disease. In our two presentations, the good response to single antibiotic treatment, although the optimal therapeutic approach is not yet defined, and the lack of embolism phenomena are of special interest. Spectrum of bacteria which can be responsible of infective endocarditis is widening rapidly; this study is an example of this trend.
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PMID:[Actinobacillus actinomycetemcomitans infectious endocarditis. Apropos of 2 cases and review of the literature]. 383 41

Geriatric medicine differs from internal medicine not in quality, but rather in the probability structures of diagnosis and outcome, presentation of illness and the need for explicit determination of aim of intervention. Older people need more investigation than the young if comparable levels of diagnostic accuracy are to be obtained. In view of the progressive loss of adaptability with its loss of sufficient functional and social reserves, the old more often need a formal program of rehabilitation than younger patients. Infectious diseases exemplify this difference. Age associated impairment of immunity, such as lower T-cell activity and IL-2 production, are associated with an increasing lethality of infections, and permit the reactivation of latent infections. The loss of adaptability has its impacts on mental functioning by increasing the risk of delirium as a consequence of infectious diseases or drug side effects. The cryptic presentation of illness makes even severe infections such as endocarditis, peritonitis or tuberculosis difficult to diagnose. The traditional exclusion of older people from research studies contributed to the still prevailing underestimation of the complexity and need of adequate therapy in geriatric patients.
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PMID:General medicine and geriatrics, where is the difference? The example of infective disease. 748 43