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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Questions regarding the relative frequency of vascular complications in nontyphoid Salmonella bacteremia are pending, and the true population-based age-related incidence is not known. We reviewed all cases of nontyphoid Salmonella bacteremia during a 10-year period from 1994 through 2003 in a well-defined population of 492,843 residents in North Jutland County, Denmark. 77 of a total of 111 cases occurred in patients >50 years old. In this age group, five cases of mycotic aneurysm and two cases of endocarditis were documented, corresponding to a 9% occurrence. The annual incidence rate of endovascular nontyphoid Salmonella infection in this age group was 4.4 per 1,000,000 person years. The mortality was 43% in cases with endovascular infection, and surgical procedures were important for survival. We conclude that in patients older than 50 years, detection of nontyphoid Salmonella bloodstream infection should be followed by examinations for mycotic aneurysms and endocarditis.
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PMID:High incidence of intravascular focus in nontyphoid Salmonella bacteremia in the age group above 50 years: a population-based study. 1694 17

We report a case of thoracoabdominal aortic aneurysm (TAAA) due to Salmonella Enteritidis making final diagnosis difficult. A 63-year-old man with a history of diabetes mellitus, hypertension, and cerebral infarction was seen elsewhere for a 40 degrees C fever, vomiting, and shaking on day 1 after onset. He was diagnosed with Salmonella bacteremia and hospitalized by us for intensive care. Computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound imaging did not, however, show critical findings of aneurysm, endocarditis, or osteomyelitis, and laboratory testing suggest significant inflammatory symptoms. He did not respond to antibiotics, but had an intermittent low fever during the first hospitalization. On day 48 after onset during the second hospitalization, abdominal CT showed an aneurysm -3 cm in diameter in the thoracoabdominal aorta above the renal artery- small enough to have been missed in earlier diagnosis. Surgery and TAAA graft replacement were done on day 64. Bacterial culture of the graft showed no Salmonella growth due to long-term in vivo antibiotic exposure. He recovered without significant complications, with oral ciprofloxacin antibiotic therapy continued to the present. This case indicates the importance of an early diagnosis through continuous blood culture and imaging for Salmonella sp blood stream infection.
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PMID:[A case of Salmonella-infected thoracoabdominal aortic aneurysm making final diagnosis difficult]. 2170 50