Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 19 year old woman presented with chest pain after a dental extraction for a dentoalveolar abscess. Electrocardiographic and serum isoenzyme changes were consistent with acute anterior myocardial infarction. At autopsy bacteria were demonstrated, within the myocardium in the absence of a myocardial abscess or endocarditis. This case illustrates the occurrence of isolated acute bacterial myocarditis after a dental extraction.
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PMID:Fatal acute bacterial myocarditis after dentoalveolar abscess. 44 82

Cardiogenic embolism has accounted for one in six ischemic strokes in recent clinical studies. We review the recent clinical literature about the natural history, diagnosis, and management of cardioembolic stroke. Long-term anticoagulation may be indicated for primary stroke prevention in high-risk patient subgroups with non-rheumatic atrial fibrillation. The prevalence of left ventricular thrombi, and probably also emboli, following an acute anterior myocardial infarction has been reduced by heparin, but the value of subsequent oral anticoagulation for persistent left ventricular thrombi has been disputed. Two clinical subgroups of mitral valve prolapse have been emerging: one benign and the other prone to complications, including embolism. Paradoxical embolism has increasingly been reported as contrast echocardiography has permitted a reliable diagnosis of patent foramen ovale. The embolic risk of infective endocarditis is low (less than 5%) when infection is controlled; early embolism during uncontrolled infection does not strongly predict later stroke. Low-intensity anticoagulation (international normalized ratio, 2.0 to 3.0) may be sufficient prophylaxis for many embolism-prone cardiac disorders.
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PMID:Cardiogenic brain embolism. The second report of the Cerebral Embolism Task Force. 185 32

A 65-year-old man was hospitalized with persistent fever (up to 39 degrees C) of 3 weeks' duration 9 years after aortic valve replacement with a Hall-Kaster prosthesis. Multiple blood cultures demonstrated beta-Streptococcus. Transesophageal echocardiography disclosed mobile vegetations at the prosthetic valve with normal valve function. A diagnosis of late prosthetic valve endocarditis was made. Therapy was begun with penicillin G, cefazolin, and gentamycin. On the 20th hospital day, he suddenly developed severe chest pain. Electrocardiography was consistent with acute extensive anterior myocardial infarction. Coronary angiography revealed that the left anterior descending coronary artery was occluded in its proximal portion with an intraluminal filling defect, which was morphologically the same as the vegetation that had been demonstrated previously. Percutaneous transluminal coronary angioplasty was performed, and coronary artery perfusion was restored 4.5 hours after the onset of chest pain. Transesophageal echocardiography performed 2 days later revealed that the vegetation at the prosthetic valve level had nearly disappeared. This is the first reported case of coronary angioplasty in a patient with acute myocardial infarction caused by prosthetic valve endocarditis in Japan.
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PMID:[Successful coronary angioplasty in a patient with acute myocardial infarction caused by prosthetic valve endocarditis]. 906 26

A 39 year old woman presented with acute anterior myocardial infarction. At coronary angiography the distal left anterior descending coronary artery (LAD)was occluded despite otherwise normal coronary arteries. The LAD was successfully recanalized using PTCA. Subsequently, a transesophageal echocardiogram revealed vegetations and a significant incompetence of the mitral valve. Blood cultures identified out enterococcus faecalis. Despite intra-venous antibiotic treatment guided by sensitivity testing, the patient ultimately required elective mitral valve replacement. During a prior outpatient diagnostic work-up of fever/malaise, the diagnosis of infective endocarditis was not made.This case conveys two main messages: 1) because the history and physical sings of bacterial endocarditis can be subtle or non-specific, the first step to diagnose infective endocarditis is to include it in the differential diagnosis. 2) Percutaneous coronary intervention is an effective treatment of septic embolic occlusion of a major coronary artery.
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PMID:Mitral valve endocarditis: an uncommon cause of myocardial infarction. 1457 47