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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The possibility of acquiring a viral infection by blood transfusion, although recognized for nearly 20 yr, is often ignored. Surgeons and internists submit patients to sophisticated, and sometimes invasive, diagnostic and therapeutic procedures without considering this possibility. We report here on two patients in whom febrile illness appeared about 5 wk after surgery. Both had received multiple blood transfusions in the perioperative period. Initial diagnoses indicated typhoid fever in one patient who received chloramphenicol therapy, and endocarditis in the other patient who was given massive combined antibiotic therapy. Both were later diagnosed by serologic methods as having cytomegalovirus and Epstein-Barr virus infection, respectively. Review of the literature reveals that this mechanism of acquiring these frequently asymptomatic viral infections is surprisingly common.
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PMID:Late postoperative fever--viral infection following multiple blood transfusion. 630 80

An original methodological approach to the diagnosis of Epstein-Barr virus (EBV) infection is proposed, consisting in the detection of viral DNA in peripheral blood lymphocytes using in situ DNA hybridization. EBV DNA was found in 6 (50%) patients with lymphomas and in 1 (33%) with infective endocarditis out of 26 examined recipients of blood components. No EBV DNA was found in peripheral blood lymphocytes of 14 regular donors. Normalization of the immune status of a patient and use of blood components containing no EBV is the key factor in the prevention of EBV infection. Biohit test system for in situ hybridization of EBV DNA may be used for diagnostic monitoring of EBV infection and screening of blood and tissue donors.
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PMID:[Method of diagnosis of Epstein-Barr virus infection]. 899 77

Splenic infarction is a rare feature of infectious mononucleosis (IM) due to Epstein-Barr virus (EBV), limited to three case reports. We report the first case of splenic infarction during acute EBV infection associated with the transient induction of antiphospholipid antibodies. We discuss the role of antiphospholipid antibodies in thrombosis in acute viral infections and postulate other mechanisms of thrombosis. Once other more common causes of splenic infarction, such as endocarditis and lymphoma, have been excluded, the possibility of viral-induced antiphospholipid antibodies should be considered.
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PMID:Splenic infarction due to transient antiphospholipid antibodies induced by acute Epstein-Barr virus infection. 1572 31

Over 26 years, we found 46 infectious episodes in 350 kidney transplant recipients. Fifteen were urinary tract infections, recurrent in 4 patients. There were 8 cytomegalovirus infections, three of them fatal when intravenous (IV) ganciclovir was not available. Seven patients had a reactivation of tuberculosis (TB) in the pleura, cervical spine, lumbar spine, knee, ankle, skin and peritoneum, respectively, and were all resolved satisfactorily with conventional anti-TB therapy. Three patients transplanted before routine prophylaxis with the use of acyclovir developed an extensive herpes zoster infection in the 1st 6 months after transplantation, which was resolved with the use of oral acyclovir, and 1 had a disseminated herpes simplex infection resolved with the use of IV acyclovir. Three patients transplanted before routine prophylaxis with trimethoprim sulfa developed Pneumocystis carinii pneumonia in the 1st 6 months after transplantation, which was fatal in one of them. In 2 patients, we found a Nocardia infection, confined to the lung, which was cured in one of the cases and systemic and fatal in the other. Two patients transplanted before routine prophylaxis with the use of nystatin developed esophageal candidiasis in the 1st 6 months after transplantation. One patient developed infective endocarditis in a stenotic bicuspid aortic valve and died 10 years later after another incident of infective endocarditis at the prosthetic aortic valve. Two patients developed an extensive condyloma at the penis, perianal region, and perineum owing to human papillomavirus, requiring extensive surgical resection and podophyllin applications. Another patient developed fatal post-transplantation lymphoproliferative disease due to Epstein-Barr virus infection 15 years after transplantation. One patient developed a severe and fatal mucocutaneous leishmaniasis with no response to conventional antimonial therapy. It is interesting to note that despite Chagas disease being endemic in Bolivia, we had no patients with reactivation or transmission through the graft even though many of the patients and donors were serologically positive for Chagas disease.
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PMID:Post-transplantation Infections in Bolivia. 2711 22