Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 35 year old man presented to his general practitioner with severe right shoulder pain and subsequent weakness and wasting of the muscles in the affected shoulder girdle three weeks after a dental filling. His symptoms persisted despite standard treatment. He developed malaise, night sweats, weight loss, a petechial rash and a microcytic anaemia. On admission to hospital three months after the start of his symptoms he had also developed splenomegaly and the murmur of aortic regurgitation. Investigations confirmed the diagnoses of infective endocarditis and neuralgic amyotrophy. In this case neuralgic amyotrophy appears to have been the presenting feature of infective endocarditis. This association has not previously been described.
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PMID:Neuralgic amyotrophy as a presenting feature of infective endocarditis. 1106 Jan 47

Whipple's disease is a very rare systemic infection caused by the bacterium Tropheryma whipplei. If untreated it can be fatal. Approximately one thousand infections caused by this microorganism have been reported globally. Our two patients with Whipple's disease suffered from weight loss, diarrhea and abdominal pain and distention, and were diagnosed with microcytic anemia and significant hypoalbuminemia. In the third patient the manifestation was blood culture negative endocarditis causing aortic insufficiency, atrial fibrillation and coronary embolisation. Antimicrobial drug therapy was effective for all three patients.
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PMID:[Whipple's disease--a rare and severe systemic infection]. 2302 54