Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Based on the observation that adenomatous carcinomas are frequently associated with tumor endocarditis, whereas undifferentiated tumors are not, autopsy material of tumor cases was examined for differences in the immune response with regard to the histological typing of the tumors. In the former group signs of stimulated cellular and humoral immune mechanisms were markedly stronger developed than in the latter group. From these findings it is suggested that tumor endocarditis represents an immune complex disease.
 ...
PMID:[Association between tumor immunology, stromal reaction, and tumor endocarditis (author's transl)]. 12 44

Only nine cases of Q fever were recorded in Canada in the 20 years prior to 1978. In the 18 months from August 1979 to January 1981 the disease was diagnosed serologically in six patients from the Maritime provinces. All were epidemiologically unrelated and none had been exposed to animals. Five had pneumonia and one had chronic Q fever with probable prosthetic valve endocarditis. Three of the five pneumonia patients presented with signs and symptoms of an acute lower respiratory tract infection and were indistinguishable clinically from other patients with atypical pneumonias. The other two with pneumonia presented with nonresolving pulmonary infiltrates and complained of decreased energy. Four of the five pneumonia patients responded well to treatment with erythromycin; the fifth required two courses of tetracycline. The patient with chronic Q fever had a large amount of cryoglobulins in his serum and evidence of immune complex disease. These cases indicate that Q fever should be considered as a possible cause of atypical pneumonia in Canada.
 ...
PMID:Q fever in maritime Canada. 707 57