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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases of gonococcal endocarditis and their clinical features have been described. This uncommon disease typically presents in a subacute fashion but may progress to a rapidly destructive, lethal process within days. We therefore recommend a conservative approach to therapy for disseminated gonococcal infection.
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PMID:Gonococcal endocarditis. 744 61

In the postantibiotic era, systemic complications from a gonococcal infection are rare. Females tend to have a higher frequency of gonococcal sepsis than males. In contrast, males have a higher rate of gonococcal endocarditis. This article describes a case of a previously healthy young male who presented with aortic insufficiency and blood cultures positive for Neisseria gonorrhoeae. Despite adequate antibiotic coverage, the patient's aortic insufficiency worsened, requiring aortic value replacement before discharge from the hospital. The patient's recovery was uneventful.
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PMID:Gonoccocal endocarditis. 869 95

There is mounting evidence that patients with systemic lupus erythematosus (SLE) are prone to disseminated neisserial infections. We describe the first proven case of gonococcal endocarditis affecting the pulmonary valve in a patient known to have SLE. The clinical clues and pitfalls in diagnosis are discussed, and the role of echocardiography is highlighted. Possible reasons for the association of gonococcal endocarditis with SLE include pre-existing Libman. Sacks endocarditis, complement deficiency and abnormalities of the reticuloendothelial system.
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PMID:Gonococcal endocarditis in a patient with systemic lupus erythematosus. 913 45

Gonococcal endocarditis is a rare but aggressive infection that has an alarming rate of perivalvular abscess and mortality. We present a case of gonococcal endocarditis with intracardiac abscess and fistula diagnosed by transesophageal echocardiography. Given the often acute nature of gonococcal endocarditis and its propensity toward abscess formation, transesophageal echocardiography should be considered early in the course of this infection.
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PMID:Gonococcal endocarditis: assessment by transesophageal echocardiography. 916 60

This report describes a case of gonococcal endocarditis in a 28 year old male patient with no history of previous valvular heart disease. More cases of gonococcal endocarditis (a rare complication of gonorrhoea) may occur with the increase in the incidence of gonorrhoea and the increase in resistance to ciprofloxacin, which is currently used as the first line agent for the treatment of gonorrhoea in 75% of genitourinary medicine clinics.
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PMID:Gonococcal endocarditis: a rare complication of a common disease. 1522 Mar 79

Acute septic arthritis is a medical emergency both for its diagnosis and its treatment. There are numerous predisposing factors of this condition. Staphylococcus aureus is the most frequent isolated bacteria. In 15% of cases, the clinical picture is not a monoarticular involvement, but rather a polyarticular one. Diagnosis is based on the identification of the micro-organism by joint aspiration and/or blood cultures. These bacteriological samples have to be realized before antibiotics administration. Cultures remain negative in 10 to 20% of true cases of septic arthritis. The antibiotic treatment has to be started when the direct Gram stain examination is positive (50% of cases) or if the suspicion is high but the Gram stain negative. It is frequently necessary to search for an associated endocarditis. It is necessary to remember the possibility of a gonococcal arthritis (tenosynovitis, skin lesions). Joint drainage can be achieved either by closed-needle aspiration or by surgical drainage (hip, destructive lesions on radiographs, no satisfactory response to medical aspirations). Duration of antibiotic treatment varies between 6 and 12 weeks, with the exception of gonococcal arthritis (10 days).
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PMID:[Acute septic arthritis]. 1769 78

The Aptima Combo 2 assay is proposed as a rapid method of diagnosing Neisseria gonorrhoeae endocarditis or other suspected disseminated gonococcal disease.
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PMID:Neisseria gonorrhoeae endocarditis confirmed by nucleic acid amplification assays performed on aortic valve tissue. 1910 81

(1) An acute gonorrhoeal urethritis may be the starting point for a grave general septicaemia with all its possible complications. (2) These infections may be mixed or secondary, due to the entrance into the circulation of organisms other than the gonococcus, or they may be purely gonococcal in nature. (3) Endocarditis is an occasional complication of gonorrhoea. (4) This endocarditis may be transient, disappearing with but few apparent results, or it may leave the patient with a chronic valvular lesion, or it may pursue a rapidly fatal course with the symptoms of acute ulcerative endocarditis. (5) The endocarditis associated with gonorrhoea is commonly due to the direct action of the gonococcus, hut may be the result of a secondary or mixed infection. (6) Pericarditis may also occur as a complication of gonorrhoea, but it is less frequent than endocarditis. It may, as in the case of the latter, be the result either of a pure gonococcal or of a mixed infection. (7) Grave myocardial changes, necroses, purulent infiltration, embolic abscesses are common in the severe gonococcal septicaemias. (8) In instances of gonococcal septicaemia the diagnosis may, in some cases, be made during life by cultures taken from the circulating blood according to proper methods.
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PMID:A SECOND CASE OF GONORRHOEAL SEPTICAEMIA AND ULCERATIVE ENDOCARDITIS WITH OBSERVATIONS UPON THE CARDIAC COMPLICATIONS OF GONORRHOEA. 1986 2

Disseminated gonococcal infection (DGI) occurs in 1-3% of all gonococcal infections; endocarditis is a complication in 1-2% of patients with DGI. We present the fourth reported case of gonococcal tricuspid valve endocarditis, this one occurring in a 53-year-old male with a 2-month history of shortness of breath.
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PMID:Tricuspid valve gonococcal endocarditis: fourth case report. 1990 Aug 29

Gonococcal infection is a common sexually-transmitted infection in the older male population in our local setting. It is caused by Neisseria gonorrhoeae, and results in fever, dysuria and a foul-smelling discharge from the external urethral meatus. Occasionally, it may also present with disseminated gonococcal infection - dermatitis, septic arthritis and even meningitis or endocarditis. We present two unusual cases, where the primary presentation was that of multiple subcutaneous hand and wrist abscesses. This illustrates the need for competent history-taking, especially in culture-negative patients. We also recommend the use of gonococcal polymerase chain reaction tests in patients who demonstrate negative routine cultures, or in lieu of gonococcal culture when the diagnosis is equivocal or urgently required.
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PMID:Culture-negative hand abscesses in immunocompetent individuals. 2233


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