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Query: UMLS:C0014118 (endocarditis)
 15,629 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The paper describes the results of 100 annuloplastic operations for the mitral valve with the aid of support rings of varying constructions. Hospital mortality rate was 10%, late mortality rate 4.6%. Five-year survival was 85.5%. In 87.1% of patients the result was good or satisfactory. Unsatisfactory results are due to the initial state of the valve (gross fibrosis, subvalvular adhesions, calcinosis), exacerbation of rheumatic carditis, septic endocarditis. Six patients with unsatisfactory results were reoperated. In 5 the valve was replaced by artificial prosthesis, in one case additional sutures were placed on the fixing ring.
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PMID:[Results of the lst 100 open-heart operations for mitral valve annuloplasty]. 731 Dec 72

We report the case of a 67 years old woman diagnosed of CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, telangiectasias) variant of generalized scleroderma, that suffered a Brucella endocarditis on mitral valve affected by the primary disease. We examine the cardiac lesions in progressive systemic sclerosis, pointing up the rare involvement of the valves, together with the evolution and treatment of Brucella endocarditis, uncommon entity.
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PMID:[Brucella infective endocarditis on sclerodermic mitral valve. Report of a case]. 823 16

Splenic arterial aneurysms (SAA) are rare and are usually atherosclerotic and/or related to pregnancy. Because pregnancy is the most important predisposing factor, the strong predilection of SAA for women is not surprising. The authors report a case of SAA rupture in a man with chronic pancreatitis as the predisposing factor. A 56-year-old man with abdominal pain and hematemesis was resuscitated and underwent endoscopy, but he died 18 hours later of massive hematemesis before definitive surgery could be carried out. At autopsy, there was chronic pancreatitis with fibrous adhesions tethering the tail of the pancreas, spleen, and posterior wall of the stomach together. The SAA was indented into the posterior wall of the stomach, into which it had ruptured from without. He also had alcoholic cirrhosis but no esophageal varices or conventional gastric ulcers. Other important predisposing factors such as abdominal trauma, infective endocarditis, polyarteritis nodosa, and segmental medial arteriopathy were absent. Histologic examination confirmed the rupture of the SAA. The SAA had Monckeberg medial calcinosis but little evidence of atherosclerosis. The well-documented complications of acute and chronic pancreatitis include shock, abscess, pseudocyst formation, and duodenal obstruction. This report describes the rare complication of SAA rupture, which may be fatal.
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PMID:Fatal splenic arterial aneurysmal rupture associated with chronic pancreatitis. 1219 58

Bakulev Scientific Center for Cardiovascular Surgery resumed research into cryopreservation and creation of valve bank in 1990. This technology allowed preparation of valve allo-grafts with preserved cell reproductive capacity for clinical use. A new technology, allowing reduction of calcinosis in the graft's aortic wall, was developed and experimentally tested in 2003. 61 aortic valve replacements with cryopreserved allo-grafts were performed between 1992 and 2003. The three techniques of implantation included: subcoronary (38), intraaortic cylinder (8) and "free-standing root" (15). 44 patients developed active infective or prosthetic endocarditis. Hospital mortality rate was 11.5%, 12-year survival rate--90%. Dysfunctions and reoperations were significantly rarer in cases of inclusion cylinder and free standing root. The authors conclude that cryopreserved allo-grafts allow good quality of life without use of anticoagulants and low rate of reinfection. The use of subcoronary technique for implantation must be limited and method of choice should be free-standing root, especially in cases of destructive infective or prosthetic endocarditis. Cellular engineering probably will elongate the stability of long-term results.
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PMID:[Cryopreserved allo-grafts in aortic valve surgery]. 1590 26

The antiphospholipid syndrome (APhS) is autoimmune non-inflammatory trombotic vasculopathy, associated with damage of vessels of any caliber and localization that determines the diversity of clinical manifestations of this syndrome. One of possible localizations of thrombosis in AphS is pseudoinfective endocarditis (PsIE). We have performed analysis of clinical and laboratory features of APhS, associated with PsIE. 28 APhS patients with PsIE, average age--44+/-13 years, were included in the study. Among them 21 patients had primary form of APhS, 7 cases had secondary form of APhS. For statistical treatment of the results the logistic regression (SPSS for Windows. Release 11.5.0.) was used, the confidence level of differences between groups was determined with the use of Student's test. Heart valve abnormalities occurred in 100% of patients and included valvular thickening, induration and sclerosis, the presence of valve vegetations, focip of calcinosis and different grade of valve dysfunction. Mitral and aortal valve vegetations occurred with the same incidence (64%), both valves were been involved in 29% of cases. Positive associations with presence/development of PsIE in APhS from multivariant model data included mitral valve lesion (OR: 0.029), focal cardiofibrosis (OR: 0.084), prior valve lesion (OR: 0.087), negative associations--hemicrania (OR: 8.627) and secondary form of APhS (OR: 6.425). Moderately high titer of lupous anticoagulant (multivariant model) (OR: 3.753) seemed to be prognostic marker of PsIE. In half of patients with APhS and PsIE systemic embolisms appeared, embolic cerebrovascular complications were the most frequent (32%). The possibility of development of hemodynamically significant valve dysfunction that needs valve replacement and nececcity of making of differential diagnosis with infective endocarditis are related to other aspects, important for clinical practice.
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PMID:[Pseudoinfectious endocarditis in antiphospholipid syndrome]. 1875 40

End stage renal disease has a list of consequences, cardiovascular being the most common. Inefficient dialysis can cause significant deposition of calcium all over the body, including heart valves making heart function impaired. We illustrate a case of 38-year-old female with end stage renal disease on peritoneal dialysis. The patient had been complaining of pain and swelling of the right hand for the last few months and had been seen by hand surgeon and was admitted electively for the biopsy of hand lesions. Before her planned surgery, she developed severe shortness of breath. Urgent echocardiogram revealed severe aortic regurgitation and large vegetation on the aortic valve. Infective endocarditis was suspected but blood cultures were negative for any microorganism and the patient did not meet the Duke criteria. Because of her hemodynamic instability immediate mechanical valve replacement surgery was performed. The pathology report showed extensive calcification and myxoid degeneration. No infectious agent was found. Later on, biopsy of her hand lesions showed extensive calcification with macrophages and giant cells. No atypia or malignancy was identified. This is a rare case of the metastatic calcinosis of aortic valve secondary to renal failure mimicking aortic valve infective endocarditis.
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PMID:Metastatic Calcinosis of Aortic Valve Secondary to Renal Failure Mimicking Infective Endocarditis. 2773 29