Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0014070 (encephalomyelitis)
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Human Gene/Protein
KLHL7 protein 11.3
Raftlin-2 11.3
Histamine receptor H1 11.3
misshapen/NIK-related kinase 11.3
Myelin-oligodendrocyte glycoprotein 10.7
myelin oligodendrocyte glycoprotein 10.6
MOG 10.4
IL-12R-beta2 10.3
raft-linking protein 10.3
modulator recognition factor 1 10.3
MOG protein 10.2
Myelin oligodendrocyte glycoprotein 10.1
PLSJ 9.8
PGG/HS 9.7
TCRBV5S2 9.7
coiled-coil domain containing 134 9.7
serine/threonine kinase 24 9.7
Tetraspanin-32 9.7
C2TA 9.3
IDD 9.2
proteolipid protein 9.1
myelin basic protein 9.1
Mog 9.0
Oct-binding factor 1 8.9
TSPAN32 8.9
IL-12 subunit p35 8.9
Retinoid-related orphan receptor gamma 8.9
STOML3 8.9
c-MIR 8.9
MBP1 8.9
MOG1 8.8
Interleukin-25 8.8
ELL3 8.7
GTP-binding protein 2 8.7
CCL11 protein 8.7
GPBP 8.7
OGFr 8.6
SLAMF9 8.4
CCDC134 8.4
Chemokine receptor CCR5 8.4
RNA binding motif protein 5 8.4
potassium channel 1 8.3
LRCH1 8.3
PCD17 8.3
ARID5A 8.3
ASR2 8.1
ELP-1 8.1
myelin P2 protein 8.0
GPR174 8.0
RRN3 8.0
oligodendrocyte-specific protein 8.0
PLP 8.0
toll-like receptor 6 7.9
interleukin 27 7.9
CD99L2 7.9
TMEM176B 7.9
C6orf4 7.8
TIMM23 7.8
pyrin domain containing 1 7.8
PLA2G4D 7.8
KIR4.1 7.8
C12orf57 7.8
IGKV3 7.8
LPHN2 7.8
CEA family member 7.8
S1P5 7.8
calcium-activated neutral proteinase 7.7
TRBV13 7.7
semaphorin 6B 7.7
MOSP 7.7
FAIM3 7.7
Raftlin 7.7
bomapin 7.7
CTRP6 7.7
IL-23R 7.7
CerS6 7.6
MBP 7.6
KLHL7 7.6
SLAT 7.6
POLR1D 7.6
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Disease
Other CNS disorders 11.3
Propionibacterium infection 11.3
Leukoencephalomyelitis 11.3
encephalomyelitis 11.3
Bhanja fever 11.3
Thogoto fever 11.3
PLSJ 10.5
Specific viral infections 10.3
infectious encephalomyelitis 10.3
Intranuclear Ophthalmoplegia 10.3
Placental necrosis 10.3
Cladosporiosis 10.3
Acute haemorrhagic leukoencephalopathy 10.3
Paraneoplastic encephalomyelitis 10.1
polioencephalomyelitis 9.8
Acute viral encephalitis 9.7
Paralytic rabies 9.7
CNS demyelinating disease 9.5
Secondary progressive multiple sclerosis 9.4
Inflammation of the central nervous system 9.3
Paraneoplastic encephalitis 9.3
polioencephalitis 9.2
Acute disseminated encephalomyelitis 9.2
IDD 9.1
Balo's concentric sclerosis 8.8
Progressive multiple sclerosis 8.7
Teschen disease 8.6
Demyelinating disorders 8.5
Streptococcus pyogenes pharyngitis 8.4
Influenza encephalopathy 8.4
Paraneoplastic retinopathy 8.4
viral CNS infection 8.4
Hydrophobia 8.4
multiple sclerosis 8.4
leukoencephalitis 8.3
VIIth nerve palsy 8.3
Atrophy of the corpus callosum 8.3
Meningoradiculitis 8.3
louping ill 8.2
Septicemic melioidosis 8.1
Avian encephalomyelitis 7.9
diffuse sclerosis 7.8
Theiler's disease 7.8
Relapsing-remitting multiple sclerosis 7.8
Multiple cranial nerve palsies 7.8
myelitis 7.6
Acute transverse myelitis 7.5
optic neuritis 7.5
Primary progressive multiple sclerosis 7.5
Brainstem encephalitis 7.4
Equine Encephalitis 7.4
Erythema chronicum migrans 7.4
Mouse hepatitis 7.3
western equine encephalomyelitis 7.3
Neuropathogenesis 7.3
radiculoneuritis 7.3
Viral encephalitis 7.2
eastern equine encephalitis 7.2
neuritis 7.2
infectious encephalitis 7.2
Neuromyelitis optica 7.1
meningomyelitis 7.0
Cranial neuropathy 7.0
perineuritis 7.0
Brain lesion 7.0
autoimmune disease 6.9
Powassan encephalitis 6.9
PSN 6.9
radiculitis 6.9
Neuroborreliosis 6.9
Cerebellar degeneration 6.9
AD4 6.8
polyneuritis 6.8
nervous system infection 6.8
acute disease 6.7
Primary HIV infection 6.7
neuromyasthenia 6.7
Russian spring-summer encephalitis 6.7
West Nile encephalitis 6.7
polyradiculitis 6.6
more...
Symptom
Limb ataxia 8.1
Koplik spots 7.5
neurological disability 7.3
unable to urinate 7.3
Flaccid paralysis 7.1
ischuria 6.6
Spastic paraparesis 6.2
Mechanical pain 6.2
meningism 6.2
abnormal reflex 5.4
myoclonus 5.3
Bell's phenomenon 5.3
Grimace 5.2
staggering gait 5.1
Lhermitte's sign 4.9
hyperesthesia 4.8
paraparesis 4.8
Neurologic symptoms 4.7
neck stiffness 4.6
monoplegia 4.5
muscle stiffness 4.5
consciousness disturbance 4.4
astasia 4.3
paresis 4.3
photopsia 4.2
visual hallucination 4.1
ataxia 4.0
cerebellar ataxia 4.0
loss of balance 4.0
startle reaction 4.0
abnormal gait 3.9
muscle rigidity 3.8
clumsiness 3.7
ataxic gait 3.7
arm weakness 3.7
spasticity 3.7
loss of taste 3.7
impaired motor coordination 3.7
Neuropathic pain 3.6
dyschezia 3.5
inanition 3.4
disturbed balance 3.4
metamorphopsia 3.3
dysarthria 3.3
auditory hallucination 3.2
hypersomnia 3.2
athetosis 3.2
functional recovery 3.2
lethargy 3.2
weakness 3.1
dysesthesia 3.0
torticollis 2.9
intention tremor 2.8
emaciation 2.8
incoordination 2.8
clonus 2.7
hemiplegia 2.6
ophthalmoplegia 2.6
chorea 2.5
fasciculation 2.5
sore throat 2.4
motor symptom 2.4
headache 2.4
pallor 2.3
seizures 2.3
anosmia 2.3
tremor 2.3
sleepiness 2.2
Decreased activity 2.2
catatonia 2.1
personality change 2.1
excessive sweating 2.1
Gastrointestinal symptoms 2.1
decreased appetite 2.1
myalgia 2.0
erythema 2.0
Fluctuation 2.0
hypertonia 2.0
rales 1.9
numbness 1.9
more...
Drug
Sophora root 10.3
Fenclorac 10.3
Lenercept 9.3
Copaxone 9.2
Actarit 8.3
Loxoribine 7.7
Fingolimod hydrochloride 7.6
Ibudilast 7.4
Roquinimex 7.3
Pixantrone 7.2
Pertussis vaccine 7.1
Glatiramer Acetate 7.1
SR 57746A 7.1
Smallpox vaccine 6.9
Natalizumab 6.7
Ferumoxides 6.7
Iguratimod 6.6
Camostat mesilate 6.4
Rabies vaccine 6.4
Batroxobin 6.3
Interferon beta-1a 6.2
Feldene 6.0
Ciglitazone 6.0
Dazmegrel 5.9
BLyS 5.9
Ocrelizumab 5.9
Diclazuril 5.8
Peridinin 5.8
Cortisporin 5.6
Lumiracoxib 5.6
Sodium benzoate 5.6
Interferon beta 5.6
IFN-gamma 5.6
Estriol 5.5
Ulinastatin 5.4
Rolipram 5.3
IFN-beta 5.3
Hyperforin 5.2
Sesame oil 5.2
Avonex 5.1
Propentofylline 4.9
Lipitor 4.9
Aminoguanidine 4.8
Ziconotide 4.8
Seroquel 4.7
Betaseron 4.7
IL-2 4.7
Miglustat 4.6
Novantrone 4.6
Methylprednisolone 4.6
Epoetin alfa 4.6
CSF 4.5
Resovist 4.5
Lipitor 4.5
Lipitor 4.5
Isoprinosine 4.5
Red ginseng 4.4
CCL 4.4
Protamine sulfate 4.3
Pepstatin 4.3
NAH 4.3
Clodronate 4.3
PDL 4.2
Cidofovir 4.2
Lovastatin 4.1
Molsidomine 4.0
Vitamin K2 4.0
Ganciclovir 4.0
Epoetin alfa 4.0
Acamprosate 4.0
Gemfibrozil 3.9
2-Methoxyestradiol 3.9
Dexrazoxane 3.9
p75 3.8
HPMPC 3.8
IL-11 3.7
Carbenoxolone 3.7
Lupron 3.6
Cilostazol 3.6
PE2 3.4
more...
Enzyme
D-dopachrome tautomerase 6.8
CNPase 6.5
bothropasin 6.5
neurosin 6.2
cholesterol 25-hydroxylase 5.8
CYP7B1 5.3
PWD 5.2
acetylesterase 5.1
PAF acetyltransferase 5.0
pyruvate dehydrogenase phosphatase 4.8
asparaginyl-tRNA synthetase 4.8
indoleamine 2,3-dioxygenase 4.7
neuropsin 4.6
prolyl-tRNA synthetase 4.6
ancrod 4.4
2A protease 4.4
caspase-11 4.4
caspase-11 4.4
macrophage elastase 4.1
MIP 4.0
N-acetylglucosaminyltransferase V 3.9
neuropsin 3.9
3-hydroxy-3-methylglutaryl coenzyme A reductase 3.9
3C protease 3.9
cathepsin S 3.9
matrix metalloproteinase 9 3.8
Thy1 3.8
kynurenine aminotransferase 3.8
granzyme B 3.8
CYP46A1 3.8
caspase-10 3.8
caspase-10 3.7
histidyl-tRNA synthetase 3.7
kynurenine 3-monooxygenase 3.7
neutrophil collagenase 3.7
arginase 3.6
N-acetylglucosaminyltransferase I 3.6
RNase T1 3.6
APC 3.5
aminopeptidase B 3.5
lysophospholipase D 3.5
inositol 3-kinase 3.4
HVS 3.3
dihydroorotate dehydrogenase 3.3
dihydroorotate dehydrogenase 3.3
cathepsin G 3.2
caspase-1 3.2
m-calpain 3.2
p80 3.2
dihydropyrimidinase 3.1
biliverdin reductase 3.1
GalT 3.1
GRK2 3.1
IMP dehydrogenase 3.0
arylsulfatase A 3.0
NO synthase 2.9
dipeptidyl peptidase IV 2.9
ADP-ribosyltransferase 2.8
monoacylglycerol lipase 2.8
bromelain 2.8
C3 convertase 2.8
tryptophanase 2.8
IKK 2.8
ADP-ribosyltransferase 2.8
peptidylarginine deiminase 2.8
histidine decarboxylase 2.7
nicotinamide phosphoribosyltransferase 2.7
sphingosine kinase 2.7
GRK5 2.7
BMT 2.7
NADPH oxidase 2.7
SNO 2.7
MMP 2.7
cathepsin C 2.7
transaldolase 2.6
NADPH oxidase 2.6
galactocerebrosidase 2.6
SCP 2.4
NPL 2.4
C3 convertase 2.4
more...
Compound
2-azaspiro[4.5]decane 9.3
9H-xanthene-9-carboxylic acid 8.9
6-ECDCA 8.4
Cyanin 8.4
Tempamine 8.3
Caerulomycin 8.1
Anatabine 7.9
Euphol 7.8
Lanthionine ketimine 7.7
PLP 7.6
Interferon beta-1b 7.4
Capsidiol 7.3
Talampanel 7.2
Dimethyl fumarate 7.1
Bisphenol A diglycidyl ether 7.0
Cuprizone 7.0
Matrine 6.9
Matrine 6.9
Matrine 6.9
Neu5,9Ac2 6.8
(aminooxy)acetic acid 6.8
Biloptin 6.7
Sulfatide 6.5
Queuine 6.5
Ro 61-8048 6.4
Ethyl pyruvate 6.4
Tamibarotene 6.4
Estragole 6.4
Nedocromil 6.3
LNFP III 6.3
Androstenediol 6.3
Pactamycin 6.2
3-pyridinol 6.0
X 13 6.0
Homotaurine 5.8
Berbamine 5.8
Methylguanidine 5.7
AICA-riboside 5.7
OLN 5.6
14,15-DHET 5.5
Alantolactone 5.5
NAAG 5.4
Methionine enkephalin 5.4
2-NP 5.3
NKT 5.2
Carnosol 5.2
Hyperforin 5.2
Mitoxantrone 5.1
Tilorone 5.1
Mitoxantrone 5.1
Sinomenine 5.1
Sphingosine 1-phosphate 5.1
Gliotoxin 5.0
Gliotoxin 5.0
Estriol 5.0
Niridazole 5.0
Bilobalide 5.0
ASN 5.0
Castanospermine 5.0
Triethylamine 5.0
Lovastatin 4.9
Cannabidiol 4.9
Phytanic acid 4.9
2-NP 4.9
BPQ 4.9
VLA 4.9
Gramicidin S 4.9
methyl hydrogen 4.8
TMF 4.8
methyl hydrogen 4.8
Minocycline 4.8
Idazoxan 4.8
N'-methylnicotinamide 4.8
Deoxypyridinoline 4.8
Deoxyspergualin 4.7
Methylprednisolone 4.7
pentanedioic acid 4.7
MPB 4.7
Diacetoxyscirpenol 4.7
Brimonidine 4.6
more...