Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0014070 (
encephalomyelitis
)
13,017
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This brief report develops the ideas of some previous works underlying a possible functional disequilibrium of tryptophan metabolism in patients affected by Multiple Sclerosis (M.S.) and in animals with experimental allergic
encephalomyelitis
. So, the urinary excretion of one of the terminal metabolites of the kynurenine pathway of tryptophan, the
N1-Methylnicotinamide
has been confronted in M.S. patients and in healthy volunteers, in order to put in evidence a possible alteration of the same in M.S. patients. The A.A. could not find any significant difference of the
N1-Methylnicotinamide
urinary output between controls and M.S. patients; afterwards they have critically revised this result.
...
PMID:N1-Methylnicotinamide urinary output in multiple sclerosis affected patients. 14 15
