Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0014070 (encephalomyelitis)
 13,017 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 42 year-old woman developed paraplegia that resolved in six months, followed by sudden right hemiparesis and dysphasia two years later. The clinical work-up, including CT and MR scans, visual evoked potential, CSF examination and cerebral biopsy suggested the possibility of either multiple sclerosis or multiphasic disseminated encephalomyelitis. The differential diagnosis between both conditions is discussed.
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PMID:Multiple sclerosis or multiphasic disseminated encephalomyelitis? A new question about an old problem. Case report. 911

We report two patients with acute cerebral conditions and zeta waves on their EEGs. The first patient, a 48-year-old lady, had acute disseminated encephalomyelitis (ADEM)following afebrile illness. Neurological examination showed expressive dysphasia and a mild right hemiparesis. The magnetic resonance imaging (MRI) scan of the brain showed multiple, bilateral, subcortical white matter hyperintensities, predominantly in the centrum semiovale region of the left hemisphere, and also in the corpus callosum. An EEG done 21 days after the onset of the neurological deficit showed intermittent, sharply contoured, predominantly biphasic delta waves (zeta waves) over the left frontotemporal region. The second patient was a 2-year-old child, who had a head-injury resulting in bilateral, frontoparietal fractures of the skull; acute epidural hematoma on the left frontoparietal region; and a cerebral contusion on the right frontotemporal region. An EEG done one day after the evacuation of the hematoma showed zeta waves over the right frontal region. To the best of our knowledge, the association of zeta waves and ADEM has not been previously reported. The EEG findings in our patients again supports the hypothesis that these waves are seen predominantly in patients with structural brain lesions. Other conditions causing zeta waves in the EEG are briefly reviewed.
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PMID:Zeta waves, an unusual EEG finding in structural brain lesions: report of two patients. 1552 72

A patient of acute disseminated encephalomyelitis (ADEM) with a rare clinical presentation is described. The temporal profile of the disease suggested parainfectious central demyelination. The magnetic resonance imaging (MRI) also showed large demyelinating lesions scattered bilaterally in the cerebral white matter, thalami and brain stem. However, clinically he had only right ataxic hemiparesis and dysphasia without any impairment of cognition or consciousness.
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PMID:Acute disseminated encephalomyelitis presenting as ataxic hemiparesis. 2950 9