Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0014070 (encephalomyelitis)
 13,017 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The myelin sheath and oligodendrocytes in the brain may be damaged by autoimmune-mediated inflammatory processes secondary to postinfectious demyelination or nutritional and vitamin deficiency. This article describes acute disseminated encephalomyelitis, acute hemorrhagic leukoencephalitis, acute necrotizing encephalopathy, and tumefactive demyelination as well as osmotic demyelination, Wernicke encephalopathy, Marchiafava-Bignami disease, and subacute combined degeneration of the spinal cord. Although some characteristic MR imaging features allow radiologists to suggest a diagnosis, these may overlap, and images should be interpreted in light of clinical symptoms and laboratory investigations.
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PMID:Neuroimaging in postinfectious demyelination and nutritional disorders of the central nervous system. 2203 2

Potentially reversible encephalopathies do add to the morbidity and mortality in critically ill patients. They are commonly seen in patients above 50 years between the 6th to 20th day of illness. Wernicke's encephalopathy, osmotic demyelination, hypoglycemia and other less common conditions like non-convulsive status, cerebral venous thrombosis and acute disseminated encephalomyelitis should be looked for in the appropriate setting as to facilitate early treatment.
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PMID:Encephalopathy in critically ill patients. 2481 54