Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0014070 (encephalomyelitis)
 13,017 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The principles of certain clinical symptoms first described at the beginning of the century are rediscovered again: Erythema chronicum migrans after tick-bite followed by numerous neurological manifestations. Meningopolyneuritis Garin-Bujadoux-Bannwarth is recognized to be a central nervous system-manifestation of Borrelian infection transmitted by tick-bites. In a period of 2 years we evaluated 15 patients with diagnosis neuroborreliosis. There is a good improvement after treatment with penicillin or ceftriaxone but there are also some cases with recidives and permanent lesions. We can also present a case report of a progressive borrelian encephalomyelitis.
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PMID:[Neuroborreliosis]. 322 64

Epidemiology and clinical presentation of Erythema chronicum migrans disease are not well known yet. During a period of only 19 months, serological and clinical investigation of 2955 patients rendered 1106 cases of infection whose widespread incidence was remarkable: of the 328 administration districts of the FRG, 205 were affected. Accordingly, positive antibodies against Borrelia burgdorferi could be demonstrated in an average of 15.7% of the investigated rural population (2830 persons). Typical clinical signs were encountered in 817 of 1106 infected persons. Erythema (458 cases) and meningopolyneuritis (404 cases) were especially prominent. In comparison to Lyme disease the occurrence of arthritis (63 cases), carditis (13 cases) multiple erythema, recurrence, and central nervous symptoms in meningopolyneuritis (10%) were rare. On the other hand, progressive borrelia encephalomyelitis (45 cases) was surprisingly common. Acrodermatitis chronica atrophicans occurred in 72 cases; lymphadenosis benigna cutis in 5 patients. The variability of this disease is demonstrated by the combined syndromes occurring in only 27% of the cases.
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PMID:Erythema chronicum migrans disease in the Federal Republic of Germany. 359 Oct 95