Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0013911 (emaciation)
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Human Gene/Protein
C20orf72 13.3
lysosomal acid beta-galactosidase 10.4
FBXL4 10.2
CDHP 9.8
C10orf2 9.6
BCS1 9.5
stem cell growth factor 9.0
IL12RB2 8.8
exonuclease 1 8.7
BPR 8.6
MICE 8.5
LBN 8.4
PolB 8.2
IFNGR2 8.2
GLB1 8.1
IL-22 receptor 8.1
IL12RB1 8.0
NADH dehydrogenase subunit 2 8.0
alpha II 8.0
swan 7.8
Hallervorden-Spatz syndrome 7.7
SOCS-2 7.7
PFD 7.7
LBC 7.6
dystrophin-associated glycoprotein 7.5
HOXB4 7.5
raptor 7.5
polaris 7.5
IFNGR1 7.5
lysosomal alpha-mannosidase 7.5
delta-sarcoglycan 7.4
IL22 7.4
beta actin 7.4
albatross 7.2
Mule 7.2
SOCS2 7.0
SOCS 6.9
CPX 6.9
RLC 6.8
ACC1 6.8
IL23R 6.7
GTT 6.7
BCS 6.7
CD204 6.7
DGAT2 6.6
C/EBP alpha 6.6
FLI 6.6
PBG 6.6
SOCS-1 6.5
fur 6.5
REC 6.4
POLG 6.4
thyroid transcription factor 1 6.4
G6PDH 6.3
EXP 6.3
L18 6.3
somatomedin C 6.3
APOB 6.3
TREK-1 6.2
CRD 6.2
XPG 6.1
beta-2 microglobulin 6.0
ESP 6.0
TBS 6.0
ASAT 6.0
argininosuccinate synthetase 5.9
ALB 5.9
SREBP-1 5.8
TEC 5.8
intestine, liver 5.8
AE3 5.8
LSC 5.8
PCB 5.8
Raptor 5.7
LCA 5.7
ADRB2 5.7
serum protein 5.7
DST 5.6
transacylase 5.6
surfactant protein C 5.5
STAT2 5.5
SP-C 5.4
HBB 5.4
utrophin 5.4
chromogranin A 5.3
p34 5.3
TCS 5.2
GPT 5.2
AE1 5.2
cytokeratin 19 5.2
GSR 5.2
parathyroid hormone-related protein 5.1
suppressor of cytokine signaling 3 5.1
WSN 5.1
DDD 5.1
MIM 5.1
Trap 5.0
adenyl cyclase 5.0
Glutathione peroxidase 5.0
TNF-a 5.0
cytokeratin 7 5.0
TM1 4.9
glutamate pyruvate transaminase 4.9
sorbitol dehydrogenase 4.9
aspartate aminotransferase 4.9
GGT 4.9
FK506 4.9
Dakar 4.9
panhypopituitarism 4.8
RDX 4.8
PID 4.8
non-active 4.8
aryl hydrocarbon hydroxylase 4.7
SOCS1 4.7
renal amyloidosis 4.7
SOCS3 4.6
BCR-ABL1 4.6
FAS 4.6
HAT 4.6
diamine oxidase 4.6
alpha-mannosidase 4.6
melanin-concentrating hormone 4.5
RCC 4.5
cox1 4.5
p51 4.5
neuron-specific enolase 4.5
PAP 4.5
SCD1 4.5
ceruloplasmin 4.4
dystrophin gene 4.4
thyroid stimulating hormone 4.4
amyloid protein 4.4
chymase 4.4
lysyl oxidase 4.4
hsp70 4.4
insulin-like growth factor I 4.4
beach 4.3
AFP 4.3
alanine aminotransferase 4.3
CD138 4.3
ghrelin 4.3
ATA 4.3
HPO 4.2
NTP 4.2
thymus 4.2
CK7 4.2
CA125 4.2
Growth hormone 4.1
NS5 4.1
alanyl 4.1
hGH 4.1
HCH 4.0
heat shock protein 90 4.0
cytokeratin 4.0
ADM 4.0
Leptin 4.0
neurofibromatosis type 1 4.0
prealbumin 4.0
growth hormone 3.9
keratin 3.9
more...
Disease
Diencephalic syndrome 14.0
Cage layer fatigue 13.3
Steatitis 12.9
acanthocephaliasis 12.9
Visceral gout 12.6
epituberculosis 12.6
Pancreatic enlargement 12.3
Chronic polyarthritis 12.1
Horizontal nystagmus 12.1
Terminal ileitis 12.1
gongylonemiasis 11.9
Cerebral atherosclerosis 11.9
Splenic atrophy 11.6
Fungal pneumonia 11.4
Cricopharyngeal achalasia 11.2
Lenz-Majewski syndrome 11.1
Toxicosis 11.0
Ulcerative proctitis 11.0
endophlebitis 11.0
Post-weaning multisystemic wasting syndrome 10.9
Afferent loop syndrome 10.7
Mammary adenocarcinoma 10.6
Canine ehrlichiosis 10.4
cystopyelitis 10.4
posthitis 10.1
Border Disease 10.0
Frohlich 9.9
hypoglobulinemia 9.9
Hypervitaminosis A 9.6
megalocytosis 9.5
Rhodesian sleeping sickness 9.5
Lumpy skin disease 9.3
Exertional rhabdomyolysis 9.3
catatonic stupor 9.3
Sarcoptic mange 9.2
Rokitansky-Aschoff sinuses 9.1
Mitochondrial DNA depletion 9.1
splenitis 9.1
Johne's disease 9.0
Lymphoid hyperplasia 9.0
hyperproteinemia 8.9
regional enteritis 8.9
Heartwater 8.9
onychogryphosis 8.8
hypothalamic disorder 8.8
Systemic inflammatory response syndrome (SIRS) 8.8
sarcocystosis 8.7
Epithelial hyperplasia 8.7
Laurence-Moon-Biedl syndrome 8.6
Brazilian spotted fever 8.6
ATE 8.5
Hallervorden-Spatz disease 8.5
keratomalacia 8.5
Bubo 8.5
isosporiasis 8.5
Aspergillus fumigatus infection 8.4
Maedi 8.4
Tubulointerstitial nephritis 8.4
Brown tumor 8.3
WDHA syndrome 8.3
cryptitis 8.3
capillariasis 8.2
anorexia nervosa 8.2
hypoadrenocorticism 8.1
Osteoradionecrosis 8.0
optic nerve glioma 7.9
hemosiderosis 7.8
hypoglycemic coma 7.8
hepatosis 7.8
pyelitis 7.7
Cronkhite-Canada syndrome 7.7
generalized tuberculosis 7.7
mineral deficiency 7.7
Recessive dystrophic epidermolysis bullosa 7.7
avitaminosis 7.7
obstipation 7.7
PFD 7.7
dermatophilosis 7.6
Erysipelothrix 7.6
dermatomycosis 7.6
enteritis 7.5
Erysipelothrix 7.5
ACTH deficiency 7.5
tropical sprue 7.5
body lice 7.5
glossitis 7.5
perihepatitis 7.4
trichuriasis 7.4
Menetrier's disease 7.4
lymphangiectasis 7.4
trypanosomiasis 7.4
Mouse hepatitis 7.3
SGS 7.3
spastic diplegia 7.2
hypobetalipoproteinemia 7.2
mesenteric lymphadenitis 7.2
bronchopneumonia 7.2
diabetic coma 7.2
Recklinghausen 7.2
coccidiosis 7.1
parakeratosis 7.1
reticuloendotheliosis 7.1
gangliosidosis 7.1
moderate obesity 7.1
acrocyanosis 7.0
periarthritis 7.0
arachnodactyly 6.9
pasteurellosis 6.9
CPX 6.9
diffuse goiter 6.8
GSD I 6.8
ear infection 6.8
roundworm 6.8
dirofilariasis 6.8
Menkes 6.8
Sertoli cell tumor 6.8
lung consolidation 6.8
lymphangitis 6.7
perforated duodenal ulcer 6.7
Aleutian disease 6.7
sparganosis 6.7
mange 6.7
xanthomatosis 6.7
episcleritis 6.7
GM1 gangliosidosis 6.7
testicular atrophy 6.7
ventriculitis 6.6
megaesophagus 6.6
Cancer cachexia 6.6
head lice 6.6
citrullinemia 6.6
wasting syndrome 6.6
osteodystrophy 6.6
mite infestation 6.6
Copper deficiency 6.5
aspiration pneumonia 6.5
lymphosarcoma 6.5
primary tuberculosis 6.4
Alexander disease 6.4
endarteritis 6.4
microcytic anemia 6.4
dehydration 6.4
Bovine tuberculosis 6.3
APOB 6.3
failure to thrive 6.3
epiphora 6.3
psychological disturbance 6.3
lice 6.3
hypochromic anemia 6.3
Hyperplasia 6.3
hyperkeratosis 6.2
coryza 6.2
insane 6.2
Arthus reaction 6.2
nephrosclerosis 6.2
non-gonococcal urethritis 6.2
ileitis 6.2
wasting 6.2
toxemia 6.1
ASAT 6.1
more...
Symptom
emaciation 14.9
Radiating pain 11.3
dysorexia 10.6
inanition 9.9
eye discharge 8.8
intestinal angina 8.8
prostration 8.7
corpulence 8.6
Lhermitte's sign 8.5
labored breathing 8.2
localized edema 8.1
Physical findings 8.1
anorexia 8.0
lethargy 8.0
astasia 7.9
lassitude 7.7
hypoproteinemia 7.7
frequent urination 7.5
pallor 7.4
ataxic gait 7.4
adipsia 7.3
decreased appetite 7.3
bradypnea 7.2
tonic seizure 7.2
pedal edema 7.1
polydipsia 7.1
polyuria 6.9
nasal discharge 6.8
ketonuria 6.8
cachexia 6.7
hepatomegaly 6.5
incoordination 6.4
abnormal gait 6.3
diarrhea 6.2
Involuntary Movement 6.2
apathy 6.2
splenomegaly 6.1
asthenia 6.1
weakness 6.1
tenesmus 6.0
colic 5.8
hyperesthesia 5.8
ataxia 5.8
excessive sweating 5.7
hypertonia 5.6
rales 5.6
ophthalmoplegia 5.5
drooling 5.5
leg edema 5.5
starvation 5.4
hepatosplenomegaly 5.4
chest tightness 5.3
intestinal bleeding 5.2
torticollis 5.2
vomiting 5.2
exertional dyspnea 5.1
clubbing 5.1
cyanosis 5.0
dysesthesia 5.0
paresis 5.0
dry skin 4.9
hypersomnia 4.8
Hudson 4.8
catatonia 4.8
dyspnea 4.7
urinary frequency 4.7
stridor 4.7
night sweats 4.7
cerebellar ataxia 4.6
myoclonus 4.4
cough 4.3
skin damage 4.3
anosmia 4.3
hemoptysis 4.3
photophobia 4.2
bloating 4.2
constipation 4.1
epigastric pain 4.1
numbness 4.1
hypothermia 4.1
shortness of breath 4.1
oliguria 4.0
hunger 4.0
hypotonia 3.9
Depressive symptoms 3.9
twitching 3.9
chorea 3.8
tense 3.8
respiratory distress 3.8
exhaustion 3.7
rhinorrhea 3.7
tremor 3.7
wheezing 3.6
tachypnea 3.6
abdominal pain 3.5
erythema 3.5
regurgitation 3.5
sleepiness 3.2
nausea 3.2
memory loss 3.1
dysarthria 3.0
fatigue 2.9
overweight 2.8
syncope 2.7
dizziness 2.6
low back pain 2.6
ENT 2.5
Ill 2.4
thinning 2.4
collapse 2.4
seizures 2.3
tinnitus 2.2
spasm 2.0
hypercapnia 1.9
headache 1.9
dystonia 1.8
chest pain 1.8
insomnia 1.5
back pain 1.3
functional recovery 1.2
pain 0.8
discomfort 0.4
discomfort 0.3
anesthesia 0.1
Drug
Fenazox 13.3
Prednisolone farnesylate 11.4
Mofezolac 11.4
Selenium sulfide 11.1
Gentian violet 9.5
Swainsonine 8.5
Mitomycin-C 7.2
Senna 6.6
Senna 6.5
Dextrose 6.2
Lugol 6.2
CVA 6.0
ISP 6.0
PFT 5.9
PPA 5.7
CFT 5.7
PCB 5.6
VCR 5.6
Ganciclovir 5.3
Gastro 5.1
Dakar 4.8
Aloe 4.6
CoCl2 4.6
CoCl2 4.6
AZT 4.5
Growth hormone 4.3
AZT 4.3
Growth hormone 4.3
VCR 4.2
Triclosan 4.2
Diurnal 4.1
Kenyan 4.1
ADM 3.3
HCH 3.1
niacin 3.0
CTX 2.4
CTX 2.4
CAM 2.4
PTH 2.1
CSF 2.0
EE2 1.9
ampicillin 1.8
ENT 1.8
CTX 1.6
Monit 1.4
Nephron 1.3
ZnO 1.1
Gel 1.0
MAP 0.9
lactose 0.8
vitamin E 0.8
Nephron 0.8
Leaf 0.5
lysine -1.0
Cardiovasc -1.7
Dermatol -3.1
Enzyme
argininosuccinate synthetase 5.4
sorbitol dehydrogenase 4.8
3-hydroxy-3-methylglutaryl-CoA reductase 4.7
aspartate aminotransferase 4.7
lysyl oxidase 4.6
chymase 4.5
transpeptidase 4.4
alpha-mannosidase 4.3
aryl hydrocarbon hydroxylase 4.2
ceruloplasmin 4.2
alanine aminotransferase 4.0
lactase 3.8
MDR 3.8
ADH 3.7
creatine kinase 3.7
alkaline phosphatase 3.7
thioredoxin reductase 3.6
diamine oxidase 3.6
MDP 3.5
gamma-glutamyl transpeptidase 3.3
AST 3.3
glucose-6-phosphatase 3.3
glutathione reductase 3.2
ricin 3.2
lipoprotein lipase 3.1
nitrate reductase 3.0
nitrate reductase 3.0
nitrate reductase 3.0
nitrate reductase 3.0
arginase 3.0
nitrate reductase 3.0
nitrate reductase 3.0
glucose-6-phosphate dehydrogenase 2.9
phosphoenolpyruvate carboxykinase 2.8
phosphoenolpyruvate carboxykinase 2.8
cholinesterase 2.8
phosphoenolpyruvate carboxykinase 2.7
lactate dehydrogenase 2.6
glutathione peroxidase 2.5
caspase-1 2.3
reverse transcriptase 2.2
lysozyme 2.1
beta-galactosidase 2.0
glutathione S-transferase 2.0
DNase 2.0
complex I 1.8
tyrosinase 1.7
elastase 1.7
catalase 1.7
alcohol dehydrogenase 1.7
lipase 1.7
CD10 1.6
acetylcholinesterase 1.1
APC 0.9
DNA polymerase 0.8
MEK 0.7
phospholipase C 0.7
endonuclease 0.7
adenylate cyclase 0.6
superoxide dismutase 0.6
proteasome 0.1
trypsin -0.5
focal adhesion kinase -0.5
peroxidase -1.1
ERK -1.7
mitogen-activated protein kinase -1.7
Compound
DASD 12.9
o-benzyl-p-chlorophenol 10.0
Nickel sulfate 9.9
2,6-DNT 8.9
Diethyl maleate 8.8
Sphinganine 8.7
Trimetrexate 8.5
A 99 8.5
aceturate 8.3
CIPC 8.3
Swainsonine 8.3
Furazolidone 7.5
TMQ 7.5
3,4-DAP 7.3
Pyrrolizidine 7.1
benzenesulfonic acid 7.1
PBG 7.0
HBC 6.9
Azan 6.9
Cyproheptadine 6.9
Miconazole 6.7
2(5H)-furanone 6.4
acenaphthylene 6.3
acenaphthylene 6.3
2,4-DNT 6.1
Fucoidan 6.1
NNN 6.0
o-cresol 6.0
TBS 6.0
Imidacloprid 5.9
Tyramine 5.9
TEC 5.8
Bantu 5.7
MHPG 5.6
MCH 5.5
PPA 5.4
DDE 5.4
HBB 5.4
Triclosan 5.3
DON 5.2
GPT 5.2
Ether 5.2
Ether 5.1
Ivermectin 5.0
Putrescine 5.0
PID 4.9
VP-16 4.8
PID 4.8
RDX 4.8
HCB 4.7
Bilirubin 4.6
Congo red 4.5
PPA 4.5
PAP 4.5
DDD 4.4
Argentine 4.4
Cap 4.4
1,3,5-triazine 4.4
FK506 4.4
1,3,5-triazine 4.4
PAS 4.3
3TC 4.3
A 1 4.2
PAP 4.2
PAP 4.2
AZT 4.2
Amphetamine 4.2
Amphetamine 4.2
TAA 4.2
PAP 4.2
A 3 4.0
SPM 3.9
ALP 3.8
CdCl2 3.8
DMI 3.8
DMI 3.8
MBC 3.8
selenium 3.7
MBC 3.7
molybdenum 3.7
Parenteral 3.6
MDR 3.6
thioglycollate 3.6
Lead 3.6
Amphotericin B 3.5
Hematoxylin 3.5
DIC 3.5
Phosphatidylinositol 3.5
Adenine 3.4
GSSG 3.4
PPD 3.4
DDT 3.4
urea 3.4
PPD 3.3
MCA 3.3
COX 3.3
Guo 3.3
BMD 3.2
mercury 3.1
CPT 3.1
Hemoglobin 3.1
CuO 3.1
Neuronal 3.0
STZ 3.0
TSH 3.0
Tyrosine 2.9
ACTH 2.9
vitamin D 2.9
creatinine 2.8
phosphorus 2.8
DHA 2.8
CAT 2.7
CAT 2.7
aflatoxin B1 2.7
DHA 2.7
Guo 2.6
CAT 2.6
xylose 2.6
retinol 2.6
Methotrexate 2.6
phenanthrene 2.5
zinc 2.5
potassium 2.5
chlorine 2.5
copper 2.5
piperazine 2.4
Cortisol 2.4
sodium chloride 2.4
gallic acid 2.4
GM1 2.3
Estradiol 2.3
Diazepam 2.2
DSM 2.2
Vitamin D 2.2
pyrimidine 2.2
DHA 2.2
glucose 2.1
pyrimidine 2.1
Lactate 2.1
vanadium 2.1
Sucrose 2.1
tungsten 2.0
H2S 2.0
DDP 2.0
Thyroid 2.0
Primatol 1.9
Primatol 1.9
TNM 1.9
barium 1.9
iron 1.9
nicotinamide 1.9
Progesterone 1.8
alcohol dehydrogenase 1.8
Adrenal 1.8
sulfuric acid 1.8
manganese 1.8
fluorine 1.8
Primatol 1.8
BCG 1.7
L-DOPA 1.7
more...