Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013911 (emaciation)
 1,059 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Beach surveys for harp (Phoca groenlaandica) and hooded (Cystophora cristata) seals documented a dramatic increase in their numbers on Sable Island in mid 1990s. In the 1980s, no more than five animals of both species were observed on this island each year, however, during late 1994 to 1998, 1,191 harp and 870 hooded seals, mostly young animals, were recorded. Although some of these seals had been killed by sharks, most (roughly 75%) were found alive or as intact carcasses on the beach, and some of the live seals were later found dead. Emaciation/starvation was considered the primary cause of death in seals that were not obviously killed by sharks. Factors that may have compounded this poor body condition included gastric impaction with abnormal ingesta, hemorrhagic diathesis possibly induced by parasitic migration and secondary vasculitis, and stomatitis (in hooded seals only). Some harp and hooded seals expanding their range in recent years may be unable to feed successfully, although the reasons for this are unclear.
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PMID:Health status of harp seals (Phoca groenlandica) and hooded seals (Cystophora cristata) on Sable Island, Nova Scotia, Canada, concurrent with their expanding range. 1268 65

In September 2004, a neonatal sea otter pup was found alive on the beach in northern Monterey Bay, CA. Efforts to locate the mother were unsuccessful. Due to a poor prognosis for successful rehabilitation, the pup was euthanized. Postmortem examination revealed emaciation, systemic lymphadenopathy and a malformation of the left cerebral temporal lobe. On histopathology, free tachyzoites and tissue cysts compatible with Toxoplasma gondii were observed in the brain, heart, thymus, liver, lymph nodes and peri-umbilical adipose. The presence of T. gondii within host tissues was associated with lymphoplasmacytic inflammation and tissue necrosis. Immunofluorescent antibody tests using postmortem serum were positive for anti-T. gondii IgM and IgG (at 1:320 and 1:1280 serum dilution, respectively), but were negative for IgG directed against Sarcocystis neurona and Neospora caninum (<1:40 each). Brain immunohistochemistry revealed positive staining for tachyzoites and tissue cysts using antiserum raised to T. gondii, but not S. neurona or N. caninum. T. gondii parasite DNA was obtained from extracts of brain and muscle by PCR amplification using the diagnostic B1 locus. Restriction enzyme digestion followed by gel electrophoresis and DNA sequencing confirmed the presence of Type X T. gondii, the strain identified in the majority of southern sea otter infections.
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PMID:Transplacental toxoplasmosis in a wild southern sea otter (Enhydra lutris nereis). 1830 37