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Query: UMLS:C0013911 (emaciation)
 1,059 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effects of the inoculation of a canine strain of rabies virus in sheep were studied using ten animals which received different amounts of this virus. Two subjects, inoculated with 10(5.4) mouse intracerebral lethal doses 50% (MICLD50), died from rabies after 19 and 40 days of incubation. Clinical signs were anorexia, emaciation, nervous reactions and prostration before death. The virus was recovered from different parts of the central nervous system and salivary glands with high titres. Only three animals showed an antibody response, at very low levels.
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PMID:[Experimental infection of sheep with a rabies virus of canine origin: study of the pathogenicity for that species]. 147 29

A total of 1300 birds in flock of breeder Pharaoh quail (Coturinix coturnix) experienced a moderate rate of mortality (13%) during a 7-day period. Clinical signs included depression, ruffled feathers, prostration, lameness, inapetence, diarrhea, and periorbital sinus swelling with mucoid discharge and lameness. Gross lesions observed in dead quail were emaciation, carcass congestion, mild hepatomegaly with green discoloration, congested intestinal mucosa, caseous purulent arthritis-osteomyelitis, and thickened crop mucosal epithelium. Histopathologic examination revealed mild hepatic amyloidosis, proliferative parabronchitis, splenic reticular cell hyperplasia, thymic cortical atrophy, subacute bacterial osteomyelitis, periarthritis, and crop mycosis. Pasteurella multocida was isolated from the joints of these birds and the isolates were serotype 3 x 4. These findings suggest that Pharaoh quail are susceptible to P. multocida and are likely to develop subacute to chronic fowl cholera.
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PMID:Subacute to chronic fowl cholera in a flock of Pharaoh breeder quail. 953 3

Johne's disease (paratuberculosis) is reported in eight goats. Clinical signs were mainly those of a chronic wasting disease which lead to emaciation, severe weakness, prostration and death. Soft pasty stool and/or profuse diarrhea were observed only after several weeks of illness, in the terminal stages of the disease, in six of the eight goats. Gross lesions were characterized by emaciation and mesenteric lymphadenopathy with more or less extensive areas of caseous necrosis and calcification. Gross lesions in the intestinal tract were limited to a mild thickening and corrugation of the mucosa of the distal small intestine, cecum and proximal parts of the colon in three of the affected animals. Caseous necrosis of Peyer's patches and ulceration were observed in two goats when small tuberculoid nodules were present in the liver of another one. Histologically, the intestinal lesions were characterized by accumulations of large foamy or vacuolated macrophages in the intestinal mucosa. Lesions were usually mild and multifocal in the proximal and middle parts of the small intestine, more diffuse and severe in the distal jejunum, ileum and proximal parts of the colon. Several of the macrophages infiltrated in the intestinal mucosa and mesenteric lymph nodes were packed with acid fast bacilli. Observations made on these animals stress the importance of a careful histological examination of the intestines and mesenteric lymph nodes of adult goats submitted to necropsy because of a chronic wasting disease.
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PMID:Johne's Disease (Paratuberculosis) in Goats: A Report of Eight Cases in Quebec. 1742 11

1. Certain anaerobically produced autolysates of pneumococcus injected intravenously kill mice in 0.1 to 0.2 cc. quantities in a few hours to 8 days. 2. The symptoms of mice inoculated with these autolysates are weakness and increasing prostration until death. Massive albuminuria is found, appearing 18 hours after injection. During the course of a prolonged intoxication ascites and edema of the subcutaneous tissues may develop. Large pale yellow or white kidneys are found in mice that survive 5 days. In these latter animals, emaciation is usually marked at death. 3. The antitoxin prepared in horses by immunization with the anaerobically prepared toxic autolysates of pneumococcus neutralizes the poisonous autolysates whether mixed in vitro before injection or injected separately after the autolysate. 4. The injection of pneumococcus autolysate toxin incompletely neutralized with autolysate antitoxin causes a protracted intoxication with symptoms and pathologic findings similar to those found in mice dying slowly after injections of the toxic autolysate alone.
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PMID:EFFECT OF ANAEROBICALLY PREPARED PNEUMOCOCCUS AUTOLYSATE TOXIN ON MICE AND EVALUATION OF PNEUMOCOCCUS AUTOLYSATE ANTITOXIN IN MICE. 1987 Mar 98

The clinical importance of heartworm infection in cats has indeed increased in recent years. Dirofilaria immitis infection has been reported worldwide in cats and continues to be regularly diagnosed in endemic areas. The diagnosis can be overlooked easily, especially in Brazil, where there is not a specific feline immunodiagnostic test, forcing the veterinarians to use a test made for the canine host. In 2015, a 10-year-old female neutered cat was diagnosed with D. immitis using an antigen serological test, based on imunocromatography and designed for dogs. The modified Knott test was negative. As the disease progressed, the cat showed clinical signals of respiratory distress, such as dyspnoea and polypnea in addition to prostration and emaciation, and died a few weeks after the diagnosis. During necropsy, one adult nematode was found in the pulmonary artery. D. immitis infection was confirmed by molecular amplification, performed in the worm fragment. This is the first report of serological diagnosis of feline dirofilariasis in Brazil. A chemoprophylaxis routine in cats should be done, as is done in dogs from endemic areas.
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PMID:Feline heartworm (Dirofilaria immitis) infection: first case report of serological diagnosis in Brazil, confirmed by molecular assay. 3006 43