Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013911 (emaciation)
 1,059 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Processes of free radical lipid oxidation (FLI), endogenic intoxication, antioxidant protection system (AOP) and morphology of a liver at tetrachlormethane hepatosis and its correction by a complete fasting have been assessed. Two chains of pathogenesis of tetrachlormethane hepatosis have been determined: the metabolic chain that is accompanied by sharp activation of free radical lipid oxidation under emaciation of antioxidant protection system and increasing endotoxemia; and the ischemic chain that enhances the processes of dystrophy and necrosis of hepatocytes and neofibrous formations. The correction by a complete fasting promoted normalization of free radical lipid oxidation at simultaneous rising of antioxidant protection system function, decreasing of a level of endogenic intoxication and conservation of hepatocytes' structure, improving recovering possibilities and prevents dystrophic and necrotic changes and neofibrous formations in the liver at tetrachlormethane hepatosis.
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PMID:[Effect of correction of tetrachlormethane hepatosis by complete fasting]. 1632 96