Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0013911 (
emaciation
)
1,059
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Canine leishmaniasis, a generally fatal
parasitic disease
, was diagnosed in 2 dogs with a medical history of foreign travel, lymphadenopathy,
emaciation
, anorexia, intermittent fever, and cutaneous lesions. Clinically, hyperproteinemia, proteinuria, azotemia, and glomerulopathy were evident. Isolation of Leishmania species was done using Schneider's Drosophila medium. Syrian hamsters were used for infectivity studies. Clear taxonomic identification was done biochemically by isoenzyme analysis and comparison of zymogram banding patterns with 6 World Health Organization reference strains. Based on the geographic origin of affected dogs, clinicopathologic presentation, visceralization with hepatosplenomegaly in hamsters, and isoenzyme analysis, a diagnosis of Leishmania leishmania infantum was made. This study, representing the first taxonomic identification of an isolate from canine leishmaniasis, demonstrates the zoonotic and epidemiologic implications of this disease.
...
PMID:Canine leishmaniasis caused by Leishmania leishmania infantum in two Labrador retrievers. 151 92
African animal trypanosomosis (AAT) is a
parasitic disease
that causes serious economic losses in livestock from anemia, loss of condition,
emaciation
and death in untreated cases. It is one of the major constraints to improved livestock production and productivity in Ethiopia. Entomological and parasitological surveys were conducted in the Omo-Ghibe tsetse belt of south Ethiopia to estimate the prevalence of bovine trypanosomosis and the apparent tsetse density (AD), and identify the potential risk factors. For the parasitological study, blood samples were collected from 1508 cattle sampled from 11 districts and assayed using the buffy coat technique and Giemsa-stained thin smears. For the entomological survey, a total of 216 biconical and NGU traps were deployed in all districts. The overall animal-level prevalence of trypanosomosis was 7.8% (95% CI: 6.5, 9.3). The trypanosome species identified were Trypanosoma congolense (75.4%), T. vivax (20.3%), T. brucei brucei (1.7%) and mixed T. congolense/T. vivax (2.6%). Regarding the entomological survey result, a total of 2243 tsetse flies were captured which identified to be Glossina pallidipes (85.1%) and G. f. fuscipes (14.9%). Besides, other biting flies of the genus Stomoxys (n=146) and Tabanus (n=17) were also trapped. The AD noted in the present study was 3.5 flies/trap/day. Both the prevalence of trypanosomosis and AD of tsetse flies were significantly (p<0.05) influenced by altitude. The prevalence of trypanosomosis was also significantly (p<0.05) associated with poor body condition score, black coat color and lower mean packed cell volume while no significant prevalence difference was noted along with age and sex category. In conclusion, the present study suggested that trypanosomosis is an important disease of cattle in the Omo-Ghibe tsetse belt in dry season. The disease is mainly caused by the most pathogenic T. congolense and transmission is predominantly by tsetse flies, particularly G. pallidipes. The study warrants the need for strengthening the vector and parasite control interventions in the area.
...
PMID:Bovine trypanosomosis and vector density in Omo-Ghibe tsetse belt, South Ethiopia. 2800 83