Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0013421 (dystonia)
 8,418 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Dystonia is a syndrome characterized by sustained muscle contractions frequently causing twisting and repetitive movements or abnormal postures. Dystonic reactions may be a complication of many drugs such as antipsychotics, anti-emetics and antidepressants. This report presents a 25-year-old patient who was admitted to an emergency department with acute dystonia following the use of varenicline, a pharmacological agent used for the treatment of nicotine addiction. Dystonic reactions may be related to the dopaminergic deficiency caused by the use of varenicline. In conclusion, this report suggests that varenicline can cause dystonic reaction in at least some patients.
Gen Hosp Psychiatry
PMID:Varenicline-induced acute dystonic reaction: a case report. 2457 87

Commentary to: CACNA1B mutation is linked to unique myoclonus-dystonia syndrome. (Hum. Mol. Genet. 2015, pp. 987-993).
Gen Physiol Biophys 2015 Jul
PMID:The first disease connection for Cav2.2 channels. 2621 36


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