Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013421 (dystonia)
8,418 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clinical and physiological examinations of 76 women in the postmenopause revealed in 64 of them the typical form of the climacteric syndrome, characterized by not only typical symptoms ("flushes", increased exudation, headaches, etc.), but also by various emotional vegetative disturbances detected at profound clinical neurological examination of the autonomic nervous system and the emotional sphere. Individual hormone therapy was associated with an appreciable alleviation of all psychovegetative disorders: "flushes", exudation, irritability, arterial hypertension, severity of vegetative dystonia, hysterical stigmata.
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PMID:[Clinical-physiological characteristics and hormone therapy of patients with typical form of climacteric syndrome]. 789 51

Overall 35 patients (20 men and 15 women aged 16 to 50 years) with consequences of craniocerebral injury of medium gravity (CCI) were examined. The standing of CCI was from 1.5 months to 6 years. On neurological examination the majority of the patients manifested non-gross organic brain deficiency and permanent symptoms of vegetative dysfunction. In 16 patients, the leading clinical syndrome was headache, in 9 vegetative dystonia, in 6 vestibulocochlear disturbances, in 3 asthenic syndrome, in 1 impairment of oculomotor innervation. In the posttraumatic period, 3 persons demonstrated complete social adaptation, 8 relative, 17 insufficient, and 7 dramatically impaired adaptation. Psychophysiological examination of the patients with consequences of CCI revealed a psychovegetative syndrome reflecting dysfunction of the nonspecific brain systems. The cardinal traits of the given syndrome are: excessive vegetative supply, derangement of the normal correlation between the desynchronizing and synchronizing brain systems in different functional conditions of daily consciousness, mental activation. In the long-term period of CCI, the risk factors, in terms of insufficient and dramatically impaired adaptation, are as follows: well-defined organic brain deficiency, premorbid personality deviations, actual psychogenias, a high level of situational and personality anxiety.
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PMID:[The nonspecific brain systems in the sequelae of craniocerebral trauma of moderate severity]. 804 65

Analysis of literature and the authors' own data suggest that laser-induced occupational disease may be diagnosed in following disorders on the part of: vision--deterioration of light and colour perception, pain and feeling of burning in the eyes; central nervous system--vegetative dysfunction, hypo- or hypertonic neuro-asthenic syndrome manifesting in weakness and fatiguability; cardiovascular system--cardialgias, hypo- or hypertonic neurocirculatory dystonia, hypertonic disease, general weakness, headache; blood--reticulocytosis; enzymes--increase of base phosphatase activity in blood. The whole complex of aforementioned disorders is quite rate (1.5-2% of cases). As a rule, only some of them are evident while sight disorders, vegetative dysfunction and increased activity of base phosphatase predominate.
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PMID:[The clinico-hygienic and experimental validation of the nosology of laser-induced disease]. 807 24

35 patients with vegetocirculatory dystonia and hyperventilation syndrome, but without the signs of organic lesion of nervous system were treated. The complex treatment included the breathing exercises with feedback mechanisms, the correction of psychovegetative and neurovascular disturbances, the massage of neck region and a head, psychotherapy, angioprotective, vegeto- and psychotropic drug therapy. The disappearance of acute vascular attacks and paroxysms of migrainous headache, the normalization of all breathing parameters and the improvement of vegetative status were observed in all patients.
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PMID:[Psychoautonomic and neurovascular disorders in patients with autonomic vascular dystonia and the hyperventilation syndrome and methods for their correction]. 853 1

26 patients with psychovegetative disorders of neurotic origin (vegetative dystonia syndrome, hyperventilation syndrome, panic attacks, headache, insomnia, motivation disorders) were treated. Light therapy (LT) was carried out every day during 2 weeks. The light of 4500-5000 lux was applied during 1 hour (the distance-60 cm). As a result positive effect was revealed in 11 patients while there was no effect in 15 individuals. The positive effect was observed as a decrease of clinical manifestations. Patients with positive treatment results were characterised by short disease duration, weak hypothalamus dysfunction, astheno-depressive disorders prevalence. Negative effect of LT was observed in patients with longer duration of disease, more severe hypothalamic dysfunction together with anxious and astheno-hypochondriac syndrome. The conclusion a made that LT effect is associated with the character and the degree of psychovegetative disorders, but not with presence or absence of hypothalamic dysfunction.
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PMID:[The phototherapy of psycho-autonomic disorders]. 899 41

We conducted a pilot study of intravenous droperidol in 35 patients (32 women and 3 men; mean age 43 years) with status migrainosus (n = 25) or refractory migraine (n = 10) in an ambulatory infusion center. Headache was graded as severe in 21 patients and moderate in 14. An intravenous line was started and kept open. Droperidol (2.5 mg) was given intravenously every 30 minutes until either three doses were given or the patient was completely or almost headache-free prior to the next dose. Seven patients received one dose, 12 received two doses, and 16, three doses (mean 5.6 mg). Our success rate (headache-free or mild headache) was 88% (22 of 25) in patients with status migrainosus and 100% (10 of 10) in patients with refractory migraine. The average time to headache improvement was 40 minutes (n = 35), to mild headache--60 minutes (n = 32), and to headache-free--105 minutes (n = 28). Nausea, vomiting, and light and sound sensitivity resolved in all but 5 patients. Four patients had an asymptomatic systolic blood pressure drop > or = 20 mm Hg. Most patients were sedated (34 of 35). Five patients developed akathisia and 1 dystonia. At follow-up 24 hours after discharge, the recurrence rate (headache intensity from none or mild to moderate or severe) was 23% in status migrainosus and 10% in refractory migraine. Twenty-one patients were sedated, while 19 had extrapyramidal symptoms, mainly restlessness. Droperidol is effective and safe in treating status migrainosus or refractory migraine. Hypotension was uncommon. Patients should be warned of sedation and akathisia.
Headache 1997 Jun
PMID:Droperidol treatment of status migrainosus and refractory migraine. 923 11

Cocaine is a substance that has significant central stimulant action in the central nervous system. As cocaine abuse spreads throughout society, many neurologic side effects are appearing with increasing frequency. These side effects include seizures, tremor, focal neurologic deficits, headache, and dizziness. Recently, there have been reports of movement disorders associated with cocaine use. Cocaine use increases the incidence of acute dystonic reactions in patients being treated with dopamine blocking agents. There have also been rare reports of cocaine causing dystonia in patients who were taking no other street drugs or medications. Our report describes the case of a patient who had an acute dystonic reaction 12 hours after a crack cocaine binge.
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PMID:Dystonia associated with crack cocaine use. 934 21

Botulinum toxin (BTx) has been administered for many years in the treatment of dystonias with great success. Its effectiveness is comparable with the best drugs. It was observed during spasmodic torticollis treatment that pain disappears as first before clinical improvement of dystonia. Different mechanisms of influence of BTx on pain are discussed. BTx was tried in tension headache, cluster headache, migraine, fibromyositis, painful cramps with varying results. It is possible that BTx will be useful in many other types of pain.
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PMID:[Botulinum toxin in the treatment of pain]. 960 54

Autogenic Training - Qualitative Meta-Analysis of Controlled Clinical Studies and Relation to NaturopathyAutogenic training is a relaxation technique based on autosuggestions and practice in the perception of 'natural' relaxating processes of the body with an increasing calm basic attitude. The psycho-physiological changes that occur after periodical exercises can be explained by a plausible model which has been empirically proved in many of its aspects. With regard to methodological aspects the present study deals with the qualitative meta-analysis of 64 controlled clinical studies from 1952 to 1997. The clinical effect of autogenic training on the main symptoms as exclusive or at least central psychotherapeutic intervention (partly in combination with a somatic basic therapy) was evaluated. It was proved that autogenic training has positive effects on psychosomatic disorders (hypertension, asthma, intestinal diseases, 'vegetative dystonia', glaucoma, atopic eczema), on preparation for childbirth, sleep disorders and anxiety disorders. A positive effect can also be expected in case of headaches and Raynaud's disease, however, other relaxation techniques seem to be superior in these cases. Moreover, positive effects on the mood (e. g. depressive symptoms) and the general subjective condition (e. g. 'quality of life') have been proved by many studies. Hence indications can be derived according to the basic rules of evidence-based medicine. Nevertheless there are contraindications, for instance regarding exogenous, acute schizophrenic or affective psychosis. Beyond that the preparedness to therapy of many patients can be improved if the therapeutic offers are enlarged by autogenic training as a 'low level' offer. Autogenic training is an effective and useful component of preventive, rehabilitative or therapeutic interventions and can last but not least be part of therapeutic interventions which include naturopathy.
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PMID:Autogenes Training - Qualitative Meta-Analyse kontrollierter klinischer Studien und Beziehungen zur Naturheilkunde. 989 18

A 76-year-old man had shown sustained excruciating facial pain in the maxillary region for more than 30 years. Since he was suffering from blepharospasm, facial electromyography was performed and revealed a perioral dystonia. This possible cause of facial pain might have been overlooked had dystonia not been considered and electromyographical studies performed. Repeated intramuscular perioral injections of botulinum toxin brought about complete pain relief. This case shows that involuntary activity of facial muscles can cause a severe chronic pain syndrome. Possible mechanisms include irritation of ascending trigeminal fibers, muscle ischemia due to compression of blood -vessels, or release of pain-producing substances.
Cephalalgia 1998 Dec
PMID:Facial pain in a case of cranial dystonia: a case report. 995 Jun 30


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