Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013421 (dystonia)
 8,418 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The pattern of nonesterified fatty acid consumption was assessed on the basis of the arteriovenous difference during the atrial stimulation test in patients with neurocirculatory dystonia and coronary heart disease. NEFA extraction coefficients were shown to be basically different in these two groups of patients, possible evidence of disturbed lipid metabolism in coronary disease.
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PMID:[Effect of myocardial ischemia on the metabolism of nonesterified fatty acids]. 272 69

Central hemodynamics, myocardial contractility and consumption of major energy substrates (lactate, glucose, non-esterified fatty acids, NEFA), as well as the total R wave amplitude from 12 standard leads were assessed in 20 patients with neurocirculatory dystonia (the control group) and 36 patients with chronic coronary disease. The changes in central hemodynamics and contractility were particularly marked in 12 of the more severe coronary cases with a raised total R wave amplitude. Myocardial energy supply in such patients is provided at the expense of NEFA. The mildest cases, whose total R wave amplitude was as low as that of the controls, showed unchanged left-ventricular contractility and normal hemodynamic response to the atrial stimulation test. Myocardial glucose and lactate extraction prevails in these patients. It is suggested that a relationship may exist between the pattern of myocardial energy metabolism and the amplitude of electrocardiographic R wave.
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PMID:[Comparison of the indices of left ventricular pumping function, contractility, myocardial metabolism and the magnitude of the R wave on the ECG of ischemic heart disease patients]. 402 Dec 98