Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0013421 (
dystonia
)
8,418
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Occupational dystonia
is a frequent clinical symptom in musicians and has been described as muscle spasms and hand cramps in pianists. Robert Schumann had a neurological impairment of his right hand that was not clinically diagnosed during his life and that impaired his career as pianist from his early 20s. This disturbance was characterized by pain and by rigidity of the fingers, which extended to other segments of his right upper extremity while he was performing and that increased with stress and improved with muscle relaxation. This disturbance produced a progressive impairment of his writing. We here hypothesize that Schumann's neurological problem was consistent with
dystonia
.
...
PMID:Did Robert Schumann have dystonia? 756 19
Primary
dystonia
is believed to be rare, and its estimated prevalence is roughly around 10-20 per 100,000 in the general population. In middle-aged or elderly people, the prevalence is much higher, reported to be over 700 per 100,000.
Dystonia
also occurs secondarily in various conditions, as drug-induced (acute or tardive)
dystonia
or in association with neurological disorders. Reported prevalence values may be underestimate. The diagnosis of
dystonia
tends to be delayed for several years after the onset of symptoms, or the symptoms may be left unrecognized or misinterpreted. "Dry eye" is common in the modern society and is a frequent misdiagnosis of blepharospasm. "Stiff sensation of the neck", a ubiquitous symptom among Japanese, may actually be a phenotype of cervical
dystonia
. A subset of "essential tremor" and tremor in SWEDDs (Scans Without Evidence of Dopaminergic Deficits) reportedly have similar pathophysiology to
dystonia
.
Occupational dystonia
is common within a specific population. About 1% of musicians may suffer from musician's
dystonia
, and about one-third of professional or highly skilled golfers may have "yips", possibly a representation of
dystonia
.
Dystonia
is common against a general belief, and should be included among the differential diagnosis in patients with muscular hyperactivity and impaired voluntary movements.
...
PMID:[Dystonia as a common status against a common belief]. 2319 18
We administered the Revised Neo Personality Inventory (NEO-PI-R) to 92 Japanese patients with focal
dystonia
and analyzed the relation of their personality traits, affected body parts, and occupations using a decision tree method. Results show that participants' personality traits were related to their occupation rather than the body part.
Occupational dystonia
patients including musicians exhibited neurotic tendencies and a high level of anxiety. Moreover, patients with occupational upper limb
dystonia
had realistic thinking patterns. Patients with musicians'
dystonia
were open about their emotional experiences: both positive and negative.
...
PMID:[Personality traits of Japanese patients with focal dystonia-Variable classification by affected body part and occupation]. 3176 30