Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0013421 (dystonia)
 8,418 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In recent years, ,perioral dermatitis' though practically unknown in the past, has been observed rather frequently in female patients. It has proven remarkably refractory against external dermatotherapy, and numerous attempts to analyse the causality have failed. However, we very often noted certain characteristics of personality structure and social attitude in the patients afflicted with the disease. Both clinical findings and various signs of vegetative dystonia suggested psychoneurotic rather than purely somatic causes. We therefore set about to elucidate the psychic and other clinical symptoms of our patients in co-operation with a psychoanalyst and a clinical psychologist. Throughout a period of several years, this interdisciplinary teamwork helped us develop biographically and psychoanalytically oriented case studies in so-called Balint seminars. We thereby gained a better understanding of the psychodynamics in each of our cases, which enabled us to treat the disease successfully. We consider ,perioral dermatitis' a primarily psychosomatic disorder which, in most cases, responds well to short-term psychotherapy. Other findings reported in dermatological literature are controversial as to their causal interpretation, even when assuming an origin by infecting microbes. We regard bacterial and other findings as sequelae which may give rise to clinical exacerbation, yet not as genuine causes of the disease. Our conception is strongly supported by the success of psychotherapy, through which the symptomatic tetracyclin and/or corticosteroid treatment has been rendered superflous.
 ...
PMID:[Development of the psychosomatic concept of perioral dermatitis]. 94 35

Autogenic Training - Qualitative Meta-Analysis of Controlled Clinical Studies and Relation to NaturopathyAutogenic training is a relaxation technique based on autosuggestions and practice in the perception of 'natural' relaxating processes of the body with an increasing calm basic attitude. The psycho-physiological changes that occur after periodical exercises can be explained by a plausible model which has been empirically proved in many of its aspects. With regard to methodological aspects the present study deals with the qualitative meta-analysis of 64 controlled clinical studies from 1952 to 1997. The clinical effect of autogenic training on the main symptoms as exclusive or at least central psychotherapeutic intervention (partly in combination with a somatic basic therapy) was evaluated. It was proved that autogenic training has positive effects on psychosomatic disorders (hypertension, asthma, intestinal diseases, 'vegetative dystonia', glaucoma, atopic eczema), on preparation for childbirth, sleep disorders and anxiety disorders. A positive effect can also be expected in case of headaches and Raynaud's disease, however, other relaxation techniques seem to be superior in these cases. Moreover, positive effects on the mood (e. g. depressive symptoms) and the general subjective condition (e. g. 'quality of life') have been proved by many studies. Hence indications can be derived according to the basic rules of evidence-based medicine. Nevertheless there are contraindications, for instance regarding exogenous, acute schizophrenic or affective psychosis. Beyond that the preparedness to therapy of many patients can be improved if the therapeutic offers are enlarged by autogenic training as a 'low level' offer. Autogenic training is an effective and useful component of preventive, rehabilitative or therapeutic interventions and can last but not least be part of therapeutic interventions which include naturopathy.
 ...
PMID:Autogenes Training - Qualitative Meta-Analyse kontrollierter klinischer Studien und Beziehungen zur Naturheilkunde. 989 18

Examination of 85 female inpatients with psychogenic neurotic mood disorders aged from 18 to 48 years has found the following depression syndrome variants: asthenic (42 patients), anxiety (14), asthenoanxiety (15), anxiety-melancholic (14). Hypothymia both mildly or moderately expressed and psychosomatic disorders as functional disturbances of reproductive, nervous and cardiovascular systems, were found. These disturbances were qualified as somatoform disorders. The most typical was autonomic dystonia syndrome. During the course of depression, somatization of psychic disorders was increasing, being most distinct in asthenic variants.
 ...
PMID:[Psychogenic neurotic depression in women (psychopathological and psychosomatic aspects)]. 1176 6