Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0013421 (dystonia)
 8,418 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

With the use of computers it proved possible to distinguish the most informative electro- and phonocardiographic signs in variants of tonsillogenic affection of the heart and primary rheumatic carditis as the result of which the severity of the myocardial affection could be judged. These signs are very important in the choice of the treatment and in prognosis. Cardiac-type neurocirculatory dystonias are characterized by the fewest informative signs indicative of vegetative effects produced on the heart. In tonsillogenic myocardial dystrophy, the number of informative signs and their pronounced character increase, which is evidence of more complex disorders in the heart. The signs in infectious-allergic myocarditis and primary rheumatic carditis are common in character, which makes differential diagnosis difficult and calls for further research into new diagnostic methods. According to the phonocardiogram, a systolic murmur was present in patients of all the groups that were examined, which had specific features in neurocirculatory dystonia and in tonsillogenic myocardial dystrophy. No essential differences were found in myocarditides.
 ...
PMID:[Electro- and phonocardiographic changes in tonsillogenic cardiopathies and primary rheumocarditis]. 700 92

We studied the influence of activation ofpecilomycotic infection in blood on the morphofunctional state of myocardium based on the clinical and pathomorphological data. The study included 23 patients with bronchial asthma (BA) concomitant with pecilomycosis after acute viral respiratory infection; protocols of autopsies and pathological sections of the heart muscle of the patients who died from asphixy and acute cardiac insufficiency were analyzed. Histological sections showed up vascular dystonia of the microcirculation bed, arteriole spasms, wall destruction in small and medium-size vessels and the adjacent muscular tissue, stromal oedema, valvular swelling, andperiwall endocarditis. Cardiac cavities and coronary vessels contained erythrocyte-rich thrombi with ferulas of Paecilomyces at different stages of development. Clinical manifestations of destructive changes in the heart muscle developing under effect of Paecilomyces infection had the form of rhythm and conductivity disorders. The local protective inflammatory reaction of productive type had the form of intermediate and vascular-type myocarditis passing to postmyocarditic cardiosclerosis. Periodic bursts of activation ofpecilomycotic infection in blood with the accumulation of fungal phospholipase A2 and lipid metabolites produced membranotoxic effect and can play the key role in the development of atherosclerosis and hypertensive disease in patients with BA and pecilomycosis.
 ...
PMID:[Pathogenesis of myocarditis in patients with bronchial asthma and pecilomycosis]. 3029 69