Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0013421 (dystonia)
 8,418 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors report 5 patients with bipolar disorders in the context of primary idiopathic dystonia. Four patients had DSM-III-R bipolar disorder, mixed, and one had cyclothymic disorder as diagnosed using the Structured Clinical Interview for DSM-III-R (SCID). All cases of bipolar disorder manifested rapid cycling. Three patients with bipolar disorder experienced onset of this illness soon after the onset of cervicocranial dystonia (5 neck dystonia, 4 craniofacial, 2 brachial, 1 vocal cord, 1 thoracic). These cases apparently represent a first report of bipolar disorders in dystonia. Clinical management, relevant literature, and putative neurobiology are reviewed.
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PMID:Bipolar disorder in idiopathic dystonia: clinical features and possible neurobiology. 142 71

Investigated were 55 patients with slow-progredient schizophrenia and cyclothymia aged 17 to 25 with the syndrome of vaso-autonomic dystonia (VAD) accompanying their mental disorder. VAD was found in 80% of the depressive cases, hypomaniac syndromes and psychopath-like (residual) states. Each of these disorders correlated with a distinct type of VAD. In a majority of the cases VAD manifested after several years of mental disease. The study provides grounds for combined psychotropic and rational psychotherapy with an early social rehabilitating assistance. The study substantiated the necessity of psychiatric services aimed at specialized psychiatric aid to these patients in the general out-patient clinic network.
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PMID:[Autonomic vascular asthenia as a component of the psycho- autonomic syndrome in slowly progressing schizophrenia and cyclothymic disorder in young patients]. 258 4