Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0013395 (dyspepsia)
 4,879 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 346
proton pump 286
gut 174
gastrin 68
lymphoid 52
She 44
COX-2 41
phosphodiesterase 41
ghrelin 37
cholecystokinin 34
insulin 33
somatostatin 30
IgA 29
Mol 26
cyclooxygenase-2 26
hemoglobin 24
motilin 24
Pol 23
reserved 23
cyclooxygenase 22
mast cell 19
Gen 19
5-hydroxytryptamine 17
kit 17
HT3 16
5-HT4 16
chronic renal failure 16
IL-6 15
lipopolysaccharide 15
collagen 15
pepsinogen 15
cytochrome P450 15
San 14
Men 14
glucagon 14
amylase 13
MRI 13
tumor necrosis factor 13
TNF 12
acetylcholinesterase 12
lipase 12
HDL 11
alkaline phosphatase 11
C-reactive protein 11
secretin 11
superoxide dismutase 11
COX-1 11
calcitonin 11
cytokine 11
pancreatic polypeptide 10
ghrelin receptor 10
catalase 10
IL-8 10
albumin 10
substance P 10
lactase 9
Ghrelin 9
Rec 9
CD4 9
IL-10 9
mucin 9
motilin receptor 9
alanine aminotransferase 8
CCK 8
B12 8
ASA 8
5-HT3 receptor 8
ANOVA 8
opioid receptor 8
NMR 8
myeloperoxidase 8
CD8 8
MIC 7
caspase-3 7
5-HT4 receptor 7
CO2 7
CYP3A4 7
aspartate aminotransferase 7
leptin 7
nitric oxide synthase 7
IgE 7
BID 7
CYP2C19 7
vasoactive intestinal peptide 7
prolactin 7
thrombin inhibitor 7
interleukin-6 6
p53 6
functional) 6
fibrinogen 6
PAI 6
TRPV1 6
AST 6
HMG-CoA reductase 6
beta-endorphin 6
interferon 6
serum albumin 6
CD34 6
5-HT2A 6
inducible nitric oxide synthase 6
Mil 6
non-Hodgkin's lymphoma 5
CD117 5
vimentin 5
nodal 5
c-Jun 5
lactate dehydrogenase 5
CGI 5
c-fos 5
thrombin 5
histamine H2 receptor 5
P-glycoprotein 5
glucosidase 5
ferritin 5
PC6 5
guanylate cyclase 5
ABC 5
serotonin receptor 5
GABA 5
gamma-glutamyl transpeptidase 5
5-HT1B 5
GSH 5
CAS 4
AKT 4
c-kit 4
chromogranin A 4
PDE5 4
creatine kinase 4
adenosine triphosphatase 4
serotonin transporter 4
AGA 4
short form 4
smooth muscle actin 4
desmin 4
Phosphodiesterase 4
cage 4
parathyroid hormone 4
IL-4 4
glutathione peroxidase 4
p38 4
GHRP 4
ATP 4
haptoglobin 4
tissue transglutaminase 4
reductase 4
COX 4
ABO 4
ankylosing spondylitis 4
AGS 4
neurofibromatosis 4
OPD 4
CD19 4
neuronal nitric oxide synthase 4
LPS 4
cyclooxygenase 2 4
myelo 4
Polymerase 4
TNF-alpha 4
carcinoembryonic antigen 4
PDE 4
more...
Disease
dyspepsia 4879
peptic ulcer 632
gastritis 596
irritable bowel syndrome 449
gastroesophageal reflux disease 437
duodenal ulcer 348
cancer 314
gastric cancer 305
Helicobacter pylori infection 288
gastric ulcer 209
esophagitis 150
Functional dyspepsia 140
diabetes 137
depression 132
gastroparesis 125
carcinoma 121
tumor 114
dysphagia 105
atrophic gastritis 103
adenocarcinoma 95
mucosa-associated lymphoid tissue 91
anemia 86
gallstones 85
asthma 83
lymphoma 78
hypertension 74
duodenitis 72
organic disease 72
gastrointestinal disease 71
erectile dysfunction 63
rheumatoid arthritis 62
inflammatory bowel disease 62
celiac disease 54
osteoarthritis 51
arthritis 49
pancreatitis 48
H pylori infection 48
malabsorption 45
obesity 44
infectious diseases 42
dysplasia 41
cold 41
Barrett's esophagus 39
stroke 38
reflux esophagitis 35
rash 33
enteropathy 31
metastases 30
West 30
iron deficiency anemia 30
Crohn's disease 30
migraine 29
dyskinesia 29
rheumatism 29
Infection 28
hepatitis 28
osteoporosis 28
xerostomia 28
chronic pancreatitis 28
hiatal hernia 27
gastroduodenitis 26
aerophagia 26
ulcerative colitis 26
cirrhosis 25
confusion 25
Esophageal 25
carcinogenesis 25
pneumonia 25
pruritus 24
malnutrition 24
colitis 24
biliary colic 24
eosinophilia 24
dysentery 23
Best 22
heart failure 22
Helicobacter pylori gastritis 22
piles 21
tuberculosis 21
chronic renal failure 21
bronchitis 20
worms 20
bronchitis 20
myocardial infarction 20
ileus 20
breast cancer 20
fecal incontinence 19
type 2 diabetes 19
neuroticism 19
neuropathy 18
SEM 18
Zollinger-Ellison syndrome 18
cholecystolithiasis 18
Gastric Cancer 18
liver disease 17
psychological distress 17
rhinitis 17
mental illness 17
achalasia 17
bowel obstruction 17
hypercalcemia 17
cardiovascular disease 17
heart disease 16
myocardial ischemia 16
gastroenteritis 16
HIV 16
cholecystitis 15
food allergy 15
pernicious anemia 15
rumination 15
influenza 15
schizophrenia 15
renal failure 14
renal disease 14
anxiety disorders 14
hypothyroidism 14
esophageal cancer 14
idiopathic thrombocytopenic purpura 14
esophageal cancer 14
eczema 13
chronic hepatitis 13
fibromyalgia 13
epilepsy 13
chronic disease 13
Parkinson's disease 13
giardiasis 13
coronary artery disease 13
abdominal migraine 13
hepatocellular carcinoma 12
eosinophilic gastroenteritis 12
ketosis 12
thrombocytopenia 12
portal hypertension 12
pancreatic insufficiency 12
chronic obstructive pulmonary disease 12
squamous cell carcinoma 12
adenoma 12
hypercholesterolemia 12
ischemia 12
Esophagus 12
chronic pain 12
PSS 12
Esophagus 12
lactose intolerance 12
major depressive disorder 11
incontinence 11
malaria 11
incontinence 11
sleep disturbances 11
hernia 11
peritonitis 11
systemic lupus erythematosus 11
pancreatic cancer 11
acute pancreatitis 11
iron deficiency 11
Chronic gastritis 10
renal impairment 10
B-cell lymphoma 10
fatty liver 10
metabolic alkalosis 10
more...
Symptom
pain 511
abdominal pain 425
nausea 405
diarrhea 398
vomiting 328
constipation 243
heartburn 232
epigastric pain 219
headache 208
discomfort 195
discomfort 190
bloating 158
anorexia 135
fatigue 89
belching 71
nausea and vomiting 70
chest pain 67
abdominal discomfort 66
regurgitation 65
Wind 64
flushing 63
dizziness 61
insomnia 48
sleepiness 36
Gastrointestinal symptoms 33
cough 33
weakness 30
dyspnea 30
acidity 27
colic 27
stomach pain 24
back pain 24
arthralgia 22
acid regurgitation 21
chronic constipation 20
myalgia 19
asthenia 18
nasal congestion 16
seizures 15
tremor 14
abdominal fullness 13
erythema 13
anesthesia 12
decreased appetite 12
hepatomegaly 11
cachexia 11
hunger 11
hoarseness 10
chronic cough 10
spasm 10
paresthesia 10
analgesia 9
angina 9
Ill 9
overweight 8
right upper quadrant pain 8
acute abdomen 8
vertigo 8
syncope 8
intestinal bleeding 8
agitation 7
retching 6
dental pain 6
hot flushes 5
shortness of breath 5
numbness 5
halitosis 5
splenomegaly 5
Functional abdominal pain 5
cancer pain 5
exhaustion 4
dysuria 4
lethargy 4
tingling 4
low back pain 4
pallor 4
otalgia 4
polyuria 4
ataxia 4
acute abdominal pain 4
sore throat 4
atypical chest pain 4
Visceral pain 4
hyperemesis gravidarum 4
Chronic abdominal pain 4
dyschezia 4
wheezing 4
chills 4
hyperemesis 3
bitter taste 3
neuralgia 3
alexithymia 3
loss of taste 3
Early satiety 3
tenesmus 3
hemoptysis 3
swollen joints 3
bone pain 3
GI irritation 3
acute pain 3
lightheadedness 3
apathy 2
emaciation 2
incoordination 2
clubbing 2
Food intolerance 2
prostration 2
throat irritation 2
jaw pain 2
menopausal symptoms 2
abdominal cramps 2
rectal pain 2
irregular bleeding 2
strangury 2
exertional dyspnea 2
memory loss 2
epigastric distress 2
left upper quadrant pain 2
Upper abdominal pain 2
neck pain 2
catarrh 2
hypoproteinemia 2
hypothermia 2
dry skin 2
polydipsia 2
blurred vision 2
functional recovery 2
Sedation 1
Burning 1
leg cramps 1
Nasal symptoms 1
leg pain 1
Rebound insomnia 1
photophobia 1
Depressive symptoms 1
Gastrointestinal discomfort 1
Welt 1
forgetfulness 1
enuresis 1
Postoperative nausea and vomiting 1
dysosmia 1
skin damage 1
Spastic 1
hypertonia 1
upset stomach 1
feeling of malaise 1
GI pain 1
Gastrointestinal distress 1
stigma 1
loin pain 1
Musculoskeletal symptoms 1
leg edema 1
Esophageal pain 1
exertional angina 1
oliguria 1
febricula 1
change in stool 1
limb pain 1
Psychological symptom 1
Cushingoid 1
more...
Drug
Cisapride 37
Viagra 19
lactose 16
Misoprostol 15
Omeprazole 14
Dermatol 13
CIA 12
Vardenafil 12
Viagra 12
Gastro 10
Cimetidine 10
Domperidone 9
caffeine 9
Ranitidine 9
Cardiovasc 9
Ginger 8
Cimetidine 8
Monit 8
Nephron 8
Asthma 7
Peppermint 5
Nephron 5
Histamine 5
Amoxicillin 5
ascorbate 5
ABC 5
Fluorescein 5
Sucralfate 5
Bifidobacterium 4
Glycyrrhiza 4
Portal 4
Corydalis tuber 4
Tegaserod 4
Tegaserod 4
Ethanol 4
ROC 4
Rebamipide 3
Paliperidone 3
Mosapride citrate 3
lysine 3
DEL 3
Giardiasis 3
IL-2 3
Itopride hydrochloride 3
FLP 3
Mirtazapine 3
Sulpiride 3
Indomethacin 3
ampicillin 3
PTH 3
Doxofylline 2
NADH 2
Fructose 2
Glutathione 2
Gel 2
citric acid 2
Clopidogrel 2
EDR 2
Ecabet sodium 2
Atomoxetine 2
Leaf 2
Indoprofen 2
Honey 2
Xanthium 2
Nabumetone 2
IFN-gamma 2
OTC 2
ADR 2
Carbenoxolone 2
Spectrum 2
Primperan 2
Etodolac 2
TAC 2
OTC 2
Prednisone 2
Iloperidone 2
Atropine 2
Colesevelam 2
EML 1
Azithromycin 1
Voltaren 1
Singular 1
Tacrolimus 1
Cognex 1
Trospium chloride 1
Infliximab 1
THA 1
Modafinil 1
Singulair 1
Cefditoren pivoxil 1
Infliximab 1
Levitra 1
Lornoxicam 1
Aprepitant 1
Capsicum 1
Cinacalcet hydrochloride 1
Evoxac 1
CDX 1
Mezlocillin 1
Loratadine 1
Tofisopam 1
Naprosyn 1
Peppermint oil 1
Myfortic 1
Nitazoxanide 1
Check 1
Vitamin B12 1
CDX 1
Citrus unshiu peel 1
Asn 1
Cinacalcet 1
Itraconazole 1
Caraway oil 1
linolenate 1
Lactose 1
Pirfenidone 1
ADM 1
Nicorette 1
niacin 1
Aldioxa 1
Ganciclovir 1
Cevimeline 1
Bayer 1
Orion 1
Ranitidine bismuth citrate 1
Lamisil 1
Kollidon 1
Allergen 1
Pregabalin 1
GHRP 1
Kenyan 1
Frovatriptan 1
Areca 1
Gastrin I 1
Cefditoren 1
Dial 1
Rhubarb 1
Zaltoprofen 1
Hoelen 1
Nimesulide 1
Hypaque 1
Bezafibrate 1
Helium 1
Serum albumin 1
Ibandronate 1
Gastrozepin 1
Lamisil 1
Rutin 1
DPA 1
Fenbufen 1
Reminyl 1
Escitalopram 1
Digenea 1
EPI 1
Zinat 1
Coartem 1
Gastrozepin 1
Senna 1
Sevelamer 1
Aerobid 1
more...
Enzyme
urease 172
urease 172
phosphodiesterase 41
acetylcholinesterase 17
pepsin 17
alanine aminotransferase 16
aspartate aminotransferase 12
catalase 12
lipase 12
creatine kinase 11
superoxide dismutase 11
alkaline phosphatase 11
ERK 9
lactase 9
peroxidase 9
mitogen-activated protein kinase 8
gamma-glutamyl transpeptidase 8
alpha-glucosidase 7
transglutaminase 7
CYP3A4 7
AST 6
guanylate cyclase 6
cholinesterase 6
trypsin 5
invertase 5
thrombin 5
sucrase 5
ATPase 5
lactate dehydrogenase 5
P-glycoprotein 5
PDE 4
NO synthase 4
glutathione peroxidase 4
glutathione S-transferase 4
protein kinase 3
lipoprotein lipase 3
ACE 3
caspase-3 3
glutamate dehydrogenase 3
glutamate dehydrogenase 3
glutamate dehydrogenase 3
xanthine oxidase 3
alpha-amylase 3
reverse transcriptase 3
tryptase 2
AMPK 2
protein kinase C 2
CD10 2
phospholipase C 2
monoamine oxidase 2
NOS 2
chymotrypsin 2
ornithine transcarbamylase 2
carbonic anhydrase 2
lysozyme 2
lipoxygenase 2
sucrase-isomaltase 2
elastase 2
AMP-activated protein kinase 2
prolidase 2
caspase-8 2
aspartase 1
STK11 1
isoamylase 1
CYP7A1 1
glucose oxidase 1
NADPH oxidase 1
biotinidase 1
focal adhesion kinase 1
MCS 1
beta-glucuronidase 1
delta-aminolevulinic acid dehydratase 1
caspase-9 1
thromboplastin 1
xylanase 1
xylanase 1
tissue plasminogen activator 1
DD-carboxypeptidase 1
acyl carrier protein synthase 1
IKK 1
GCA 1
phytase 1
BAL 1
NADPH oxidase 1
PKG 1
prostate-specific antigen 1
N-acetyltransferase 1
BMT 1
phytase 1
ceruloplasmin 1
phospholipase A2 1
sorbitol dehydrogenase 1
xanthine dehydrogenase 1
tryptophan hydroxylase 1
proline dehydrogenase 1
cGMP phosphodiesterase 1
heme oxygenase 1
lysyl oxidase 1
GalT 1
PARP 1
PAH 1
SOR 1
KAT 1
ADH 1
AMPK 1
adenosine deaminase 1
hormone-sensitive lipase 1
LIS 1
proteasome 1
IOR 1
transpeptidase 1
zeaxanthin epoxidase 1
kallikrein 1
UDP-glucuronosyltransferase 1
tissue kallikrein 1
adenosine deaminase 1
STR 1
acetyl-CoA carboxylase 1
alcohol dehydrogenase 1
pyruvate kinase 1
tyrosine hydroxylase 1
MDR 1
CPM 1
TMT 1
adenylate cyclase 1
AFR 1
Compound
Clin 496
Dec 304
urea 147
water 104
barium 71
calcium 61
DNA 55
glucose 54
sodium 48
5-HT 41
Cisapride 37
PPI 36
ethanol 36
nitric oxide 35
Sildenafil 28
hydrogen 27
iron 25
oxygen 24
creatinine 23
salt 20
His 19
ASA 19
Omeprazole 17
acetate 16
Cardiol 16
Acotiamide 15
acetic acid 14
Bismuth 14
methanol 13
potassium 13
carbonate 13
silver 12
TNF 12
nitrate 11
arginine 11
GMP 10
Domperidone 10
benzamide 10
sulfate 10
Clarithromycin 10
nitrogen 10
glutamate 10
caffeine 9
DSM 9
Metoclopramide 8
CO2 8
ethyl acetate 7
GSH 7
ammonia 7
phenol 7
tryptophan 7
GSH 7
tryptophan 7
MIC 7
NIDA 7
cGMP 7
Curcumin 7
Ranitidine 7
phosphorus 7
tryptophan 7
tryptophan 7
Ibuprofen 6
aluminum 6
DPPH 6
acetonitrile 6
Hematoxylin 6
methane 6
6-12 6
zinc 6
GABA 5
Meloxicam 5
GABA 5
Eosin 5
Histamine 5
copper 5
nicotinic acid 5
Capsaicin 5
hydroxide 5
Piper 5
Eosin 5
Sucralfate 5
Amoxicillin 5
A 42 5
Insulin 5
galactose 5
MTT 5
nicotinic acid 5
Pentagastrin 4
PAS 4
Sumatriptan 4
Iodo 4
nicotinic acid 4
COX 4
octanoic acid 4
tin 4
Ascorbic acid 4
HCl 4
prostaglandin E1 4
DAD 4
Warfarin 4
A 3 4
phosphate 4
Optimal 4
formaldehyde 4
Luminal 4
nicotinic acid 4
octanoic acid 4
octanoic acid 4
Buspirone 4
ATP 4
Lansoprazole 4
octanoic acid 4
Pac 4
octanoic acid 4
Risperidone 4
Sulfasalazine 3
Naproxen 3
Indomethacin 3
Diclofenac 3
DDP 3
Isoproterenol 3
bromide 3
noradrenaline 3
retinol 3
2-hydroxyethyl 3
Metformin 3
Cyclosporine 3
ammonium 3
Naloxone 3
Rutin 3
Pirenzepine 3
SDS 3
2-naphthylacetic acid 3
salicylic acid 3
succinic acid 3
NMDA 3
formaldehyde 3
Dexamethasone 3
Azathioprine 3
chloroform 3
Ziprasidone 3
glutamine 3
propionic acid 3
A 71 3
PGE 3
propionic acid 3
Metformin 3
ADR 3
cysteine 3
T 1 3
Ursodeoxycholic acid 2
CAT 2
Bismuth subsalicylate 2
Abbott 2
ITP 2
PSP 2
HMG-CoA 2
TSH 2
Hemoglobin 2
8-OHdG 2
more...