Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013395 (dyspepsia)
 4,879 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The rhizomes of Zingiber officinale Roscoe (Zingiberaceae), commonly known as ginger is an important kitchen spice and also possess a myriad health benefits. The rhizomes have been used since antiquity in the various traditional systems of medicine to treat arthritis, rheumatism, sprains, muscular aches, pains, sore throats, cramps, hypertension, dementia, fever, infectious diseases, catarrh, nervous diseases, gingivitis, toothache, asthma, stroke and diabetes. Ginger is also used as home remedy and is of immense value in treating various gastric ailments like constipation, dyspepsia, belching, bloating, gastritis, epigastric discomfort, gastric ulcerations, indigestion, nausea and vomiting and scientific studies have validated the ethnomedicinal uses. Ginger is also shown to be effective in preventing gastric ulcers induced by nonsteroidal anti-inflammatory drugs [NSAIDs like indomethacin, aspirin], reserpine, ethanol, stress (hypothermic and swimming), acetic acid and Helicobacter pylori-induced gastric ulcerations in laboratory animals. Various preclinical and clinical studies have also shown ginger to possess anti-emetic effects against different emetogenic stimuli. However, conflicting reports especially in the prevention of chemotherapy-induced nausea and vomiting and motion sickness prevent us from drawing any firm conclusion on its effectiveness as a broad spectrum anti-emetic. Ginger has been shown to possess free radical scavenging, antioxidant; inhibition of lipid peroxidation and that these properties might have contributed to the observed gastroprotective effects. This review summarizes the various gastroprotective effects of ginger and also emphasizes on aspects that warranty future research to establish its activity and utility as a gastroprotective agent in humans.
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PMID:A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe). 2361 3

If one is searching for a perfect example of why the Pure Food and Drug Act of 1906 was needed, this 1901 SWANSON'S RHEUMATIC CURE CO. foldover brochure would fit the bill (Figures 1A, 1B, and 1C). The SWANSON "FIVE DROP" REMEDIES were heralded as "the faithful guardian and sentinel of the human system" that "stands at the door and challenges every germ that knocks for admittance." FIVE DROPS had an "unfailing effect in the following diseases Rheumatism in all its forms, Sciatica, Backache, Neuralgia, Nervousness, Sleeplessness, Nervous and Neuralgic Headaches, Nervous Dyspepsia, and Nervous affections of every description, Asthma, Hay Fever, Croup and Bronchitis, Catarrh, Heart Weakness, Toothache (authors' emphasis), Earache, La Grippe, Malaria, Creeping Numbness and kindred diseases." What couldn't these drops cure? A bottle of Swanson's Five Drops is pictured in Figures 2A and 2B.
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PMID:Swanson's Five Drops. 3249 39