Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013395 (dyspepsia)
 4,879 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Attempted suicide and suicide have been investigated among 2,619 patients suffering from duodenal ulcer, gastric ulcer and ulcer dyspepsia without ulcer demonstrable by x-ray. There was no difference in the percentage of attempted suicides and suicides among the three ulcer groups or between the sexes. Within well-defined periods, there was a statistically significant greater excess of attempted suicides among patients operated on than among unoperated patients. The distribution according to psychiatric diagnosis was very similar to the one observed among persons in general in Copenhagen attempting suicide. The number of patients committing suicide exceeded the expected number significantly, for men as well as for women, but there was no difference between patients operated on and unoperated patients. The psychiatric diagnoses of those committing suicide were predominantly neuroses and psychopathy.
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PMID:Ulcer, attempted suicide and suicide. 114 85

Among 1,780 male persons with duodenal ulcer, gastric ulcer and ulcer dyspepsia without ulcer demonstrable by x-ray, 737 (21%) had been convicted of law offences. There were no differences among the three ulcer groups with regard to the frequencies of the different crimes or the percentage of persons in each of the groups. The percentage of persons admitted to a psychiatric department was higher among those convicted than in the material in general. The dominating psychiatric diagnosis among those convicted was psychopathy. Among patients operated on, the percentage of convicted persons was significantly higher than among those not operated on. Among 168 persons convicted for offences committed while under the influence of alcohol, the percentage of heavy drinkers was higher than in the material in general. Only 3.1% of 771 women had been convicted for an offence. The observed frequencies of law breakers among the patients in the three ulcer group did not exceed the frequencies in the general population.
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PMID:Ulcer disease and the law. 114 86

Studies of dyspepsia show a 1% to 2% prevalence in adults, and 25% to 40% of these patients do not have a physical reason for their symptoms. These findings prompted us to do a retrospective follow-up study of 390 patients having motility studies for chest pain and gastrointestinal (GI) symptoms; 278 (71%) responded. Patients were asked to complete a self-rating symptom questionnaire regarding current GI symptoms and current symptoms of anxiety, panic, and depression; they were also asked to complete the Brief Symptom Inventory. Two groups were compared--those with known heart disease and those without heart disease. Substantial numbers of patients in both groups satisfied criteria for generalized anxiety disorders (> 70%), panic disorder (> 30%), and major depression (> 35%). GI symptoms compatible with nonulcer dyspepsia were strongly associated with a psychiatric diagnosis. Our data suggest that anxiety and depressive states are strongly associated with dyspepsia and other GI symptoms not caused by ulcer disease.
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PMID:Nonulcer dyspepsia associated with psychiatric disorder. 850 84

Systematic studies of psychiatric disorders in non -ulcer dyspepsia are rare. The aim of the present study was to find out the nature and prevalence of psychiatric morbidity in non-ulcer dyspepsia. Thirty three patients with non-ulcer dyspepsia and thirty with duodenal ulcer were assessed for psychiatric morbidity with the help of the regular version of the SADS, and diagnosed according to DSM-IIIR criteria. Non-ulcer dyspepsia was defined precisely and investigators who made the psychiatric diagnosis were blind to the gastroenterological diagnosis. In the non-ulcer dyspepsia group, 69.7% of patients had psychiatric morbidity, compared to 26.7% in the ulcer group. The difference between the two groups in the frequency of psychiatric morbidity was statistically significant. Dysthymic disorder (39.4%) was the most frequent psychiatric disorder in the non-ulcer dyspepsia group.
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PMID:Psychiatric disorders in non - ulcer dyspepsia. 2177 69

We wanted to examine the prevalence of psychiatric morbidity in patients diagnosed as having essential dyspepsia, as well as the short-term course of dyspeptic symptoms, following drug treatment of the psychiatric condition. Seventy-four patients with essential dyspepsia presenting to the gastroenterology outpatient department of a medical college were investigated for the presence of psychiatric disorder. The response to an open trial of pharmacotherapy in 50 patients with a psychiatric disorder and no other demonstrable pathology was assessed. These patients met the criteria for a DSM-III-R diagnosis, most commonly major depressive disorder (26) or generalized anxiety disorder (10). The mean age of those with a psychiatric disorder alone was significantly higher than that of those with another demonstrable pathology. With treatment, 16 patients with no demonstrable pathology other than psychiatric disorder (depression: 12; anxiety: 4) showed improvement over a period of 6 weeks in psychiatric as well as dyspepsia ratings. The difference was however statistically significant only for the group with major depressive disorder. We concluded that, despite differences in the characteristics of the population studied, a psychiatric diagnosis is associated with at least a proportion of cases with essential dyspepsia and emerges as a likely explanation.
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PMID:Psychiatric disorder in essential dyspepsia. 2494 46