Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013395 (dyspepsia)
 4,879 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Studies of dyspepsia show a 1% to 2% prevalence in adults, and 25% to 40% of these patients do not have a physical reason for their symptoms. These findings prompted us to do a retrospective follow-up study of 390 patients having motility studies for chest pain and gastrointestinal (GI) symptoms; 278 (71%) responded. Patients were asked to complete a self-rating symptom questionnaire regarding current GI symptoms and current symptoms of anxiety, panic, and depression; they were also asked to complete the Brief Symptom Inventory. Two groups were compared--those with known heart disease and those without heart disease. Substantial numbers of patients in both groups satisfied criteria for generalized anxiety disorders (> 70%), panic disorder (> 30%), and major depression (> 35%). GI symptoms compatible with nonulcer dyspepsia were strongly associated with a psychiatric diagnosis. Our data suggest that anxiety and depressive states are strongly associated with dyspepsia and other GI symptoms not caused by ulcer disease.
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PMID:Nonulcer dyspepsia associated with psychiatric disorder. 850 84

This report details the naturopathic treatment of a 28-y-old female with a 1 y history of abdominal pain, heartburn, and constipation as well as longstanding anxiety and depression. Clinical evaluation ruled out organic causes of dyspepsia such as peptic ulcer disease, Helicobacter pylori infection, and nonsteroidal anti-inflammatory drugs-induced dyspepsia. Treatment consisting of soft-tissue manipulation, homeopathic prescription, nutritional supplementation, and lifestyle modification greatly improved gastrointestinal and mental-emotional symptoms after 2 wk. Improvement in anxiety and depression was substantiated with Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 questionnaires.
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PMID:Treatment of Gastrointestinal Symptoms and Mood Disorder With Physical Medicine and Supplementation: A Case Report. 3096 96