Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013395 (dyspepsia)
 4,879 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 3-year old boy was referred to a paediatric psychiatry out-patient clinic for major disorders consisting of hyperphagia, intolerance to frustrations and instability since the age of one year, and pica (i.e. the indigestion of non-edible substances) since the age of two years. These symptoms developed in a context of greatly disturbed parent-child relations, predominantly made of ambivalence and inability to define limits and interdictions. Conversations with the family are restoring the parental roles and improving the child's symptoms.
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PMID:[Pica. Anomalies in mother-child relations]. 783 Dec 54

Pica, the purposive consumption of nonfood substances, is a millennia-old nutritional enigma. Its worldwide ubiquity, prevalence among pregnant women and children, and association with both positive and negative health outcomes, especially micronutrient deficiencies, underscore the importance of understanding this behavior. Multiple proposed etiologies of pica are reviewed, including cultural expectations, psychological stress, hunger, dyspepsia, micronutrient deficiencies (Fe, Zn, and Ca), and protection against toxins and pathogens. Currently available data, although limited, best support the protection hypothesis as a cause of most types of pica, although some evidence suggests that pagophagy (ice consumption) may occur during iron deficiency. It is possible that the binding capacity of pica substances explains the association with micronutrient deficiencies; earth, starch, etc. may render micronutrients in ingesta unavailable for absorption. Increased research efforts are warranted and must be hypothesis driven, interdisciplinary, and permit the testing of multiple causal inferences.
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PMID:Pica in pregnancy: new ideas about an old condition. 2042 May 23