Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013395 (dyspepsia)
 4,879 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Esophageal squamous papilloma (ESP) is considered to be a rare finding during endoscopy or autopsy. Over a 10 year period, 10 cases were identified among 14,232 patients who were endoscoped in the King Khalid University Hospital (KKUH), Riyadh. The calculated incidence was 0.07%. There were eight males and two females whose ages ranged from 24 to 65 years. The presenting symptoms were mostly dyspepsia and heartburn. All the ESPs were single growth, most of which were located in the lower segment of the esophagus. Immunoperoxidase staining was negative for human papilloma virus in all the tissue samples. It is calculated that ESPs may not be very rare in the Saudi population. Awareness of its occurrence may lead to increasing diagnosis among endoscopy patients.
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PMID:Squamous papilloma of the esophagus - a clinicopathologic study of 10 cases and review of the literature. 1758 24

Epiglottic masses may be cystic, granulomatous, infectious, benign or malignant neoplastic, or manifestations of a systemic disease. When large in size, the airway may become obstructed, and when accompanied by suspicious features such as cartilaginous invasion, extension to the pre-epiglottic or para-glottic spaces, or lymphadenopathy, the radiologist must consider malignancy as a primary differential diagnosis. However, when only benign features are identified, the differential diagnosis is broad. We present a 65-year-old female with an incidental 1 cm exophytic, pedunculated, papillomatous lesion on the laryngeal surface of the epiglottis discovered upon endoscopic evaluation for dyspepsia and heartburn. Because of her risk factors for malignancy, CT scan was requested and revealed only benign features. Subsequent excisional biopsy revealed a benign squamous papilloma; however, multiple additional differential considerations were entertained preoperatively.
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PMID:Epiglottic masses identified on CT imaging: A case report and review of the broad differential diagnosis. 2645 3