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Query: UMLS:C0013395 (dyspepsia)
 4,879 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The various complaints after gastroscopy and the acceptability of the procedures are verified by a questionnaire in 300 consecutively examined patients with or without gastric lesions. The extent of psychic lability, neurosis and extraversion was determined by the Maudsley Personality Inventory test of Eysenck. The time necessary for the passage of the instrument (swallowing time) and the time taken by gastroscopy were registered on each patient. More than half of the patients complained of sore throat lasting more than 1 day. Less than a quarter had abdominal dyspepsia. The intensity of the sore throat was correlated with the swallowing time but not with the extent of neurosis or gastroscopy time. 98% of the patients consented to a control examination. The necessity of a gastroscope with less diameter and a non mucosal damaging top is stressed.
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PMID:[Complaints after gastroscopy and their cause (author's transl)]. 43 72

Patients with functional dyspepsia are a heterogeneous group in whom psychologic and environmental factors and stress may contribute to their reports of symptoms. There is no unique personality profile in patients with functional dyspepsia. Although they have more anxiety, neuroticism, and depression than healthy subjects, their personality scores are no different than other patients with chronic abdominal pain syndromes, be they organic or functional in nature. Social factors including older age, male gender, unmarried status, and social incongruity are associated with increased frequency and severity of symptoms but not health-care-seeking behavior. Childhood role models with abdominal pain and the tendency to perceive negative life events as having great impact on their lives may affect the coping skills of these patients. Although patients with functional dyspepsia react to acute experimental stress with gastric physiologic changes similar to healthy subjects, their visceral pain thresholds are lower, which may contribute to their reports of symptoms. Despite common beliefs, most environmental factors such as smoking, alcohol, coffee, or use of nonsteroidal anti-inflammatory drugs are not important contributors to these patients' symptoms.
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PMID:Stress and psychologic and environmental factors in functional dyspepsia. 189 29

Patients with dyspepsia of unknown origin (DUO) and those with similar upper abdominal symptoms but with an organic cause (peptic ulcer) were assessed on personality and psychological symptom measures. The DUO patients had significantly more symptoms of anxiety and tension and higher scores for trait tension and hostility than the organic group. The two groups did not differ significantly in terms of depressive symptoms, neuroticism, psychoticism, or suppression of negative affects. The implications of these findings for the aetiology and diagnosis of DUO are discussed.
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PMID:Psychological factors in dyspepsia of unknown cause: a comparison with peptic ulcer disease. 232 5

A group of 23 non-ulcer dyspepsia patients were compared with controls drawn from relatives of psychiatric outpatients. The level of hostility in both groups was high, but not significantly different. There was also no significant difference between the 2 groups on measures of extroversion, neuroticism, psychoticism and lie scores, but the ulcer group was significantly more depressed and more were diagnosed as suffering from a neurotic depression and generalized anxiety disorder.
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PMID:Psychosocial aspects of non-ulcer dyspepsia. 281 36

The aim of this study was to describe the clinical features of patients with chronic unexplained dyspepsia and compare the symptoms with peptic ulcer and biliary pain, and determine the prevalence of symptoms that may indicate psychoneurotic traits and measure chronic illness behaviour (days lost from work and doctor visits). Studied were: 113 patients with essential dyspepsia, defined as endoscopically confirmed non-ulcer dyspepsia where gallstones, the irritable bowel syndrome and gastro-esophageal reflux have been excluded and there is no ascertainable cause for the dyspepsia; 55 patients with dyspepsia and peptic ulceration at endoscopy; and 53 patients with diagnosed biliary pain and cholelithiasis, proven at cholecystectomy. All patients completed a detailed structured history questionnaire in the presence of one investigator. More patients with peptic ulcer than with essential dyspepsia experienced night pain, pain relieved by food, and vomiting, while more patients with essential dyspepsia than with cholelithiasis experienced epigastric pain, lack of radiation of pain, continuous pain, mild to moderate pain, pain before meals, pain relieved by food and antacids, pain aggravated by food and alcohol, and an absence of vomiting (all p less than 0.01). Symptoms suggesting psychoneurosis, aerophagy symptoms, and chronic illness behaviour were similar in all groups. We conclude that certain symptoms may be of value in diagnosing the underlying cause of dyspepsia.
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PMID:Comparison of the clinical features and illness behaviour of patients presenting with dyspepsia of unknown cause (essential dyspepsia) and organic disease. 346 12

Low pressure/low flow voiding in young and middle-aged males in the absence of outflow tract obstruction has been reported as being associated with anxiety and a high incidence of dyspepsia. To assess objectively the psychological basis of this condition, an unselected group of 50 men aged 25 to 55 years was evaluated by psychiatric interview, questionnaires and urodynamic tests. In addition, patients involved in an earlier study were psychologically evaluated. Low pressure/low flow voiding was demonstrated in three (6%) of the new patients. This voiding pattern was related to a long preceding history, stress-dependent symptoms and difficulty in voiding in public urinals. When compared with a control population, the experimental group scored significantly higher on measures of psychoneurosis. It is recommended that surgery be avoided in these patients and that simple behavioural therapy may be most appropriate.
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PMID:Low pressure/low flow voiding in younger men: psychological aspects. 402 11

By means of Eysenck's Maudsley Personality Inventory (MPI), the personality dimensions neuroticism and extraversion were estimated in 1148 control probands (m. 195; f. 953), in 375 patients with x-ray negative dyspepsia (m. 233; f. 142), in 77 males with duodenal ulcer, 42 patients with gastric ulcer (m. 25; f. 17), and 27 patients with gastric cancer (m. 18; f. 9). In x-ray negative dyspepsia and in duodenal ulcer, slightly higher scores for neuroticism and lower scores for extraversion than in controls were found whereas patients with stomach cancer and gastric ulcer are characterized by high emotional stability. It is assumed that knowledge of the patient's personality structure may improve the physician-patient relationship.
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PMID:[Investigation of personality structure by MPI in patients with gastric diseases (author's transl)]. 741 41

Low vagal tone may represent a mediating mechanism for relationships between personality and symptoms of functional dyspepsia (FD) through a mechanism of antral hypomotility. Twenty-one patients with FD and seventeen healthy controls completed a series of personality tests before vagal and sympathetic activity, antral motility, and abdominal symptoms were assessed in response to a laboratory task. Functional dyspepsia patients had lower scores on vagal tone (p = .054) and motility index (p = .011) in addition to the expected higher scores on epigastric discomfort (p = .002). Psychological factors explained a substantial amount of the variance in vagal activity, antral motility, and reported symptoms. Symptoms were predicted by trait anxiety (STAI-TR), depression (BDI), and neuroticism (EPQ-N). Poor vagal tone was related to neuroticism (EPQ-N). Poor motility was best explained by task-related state dysphoria (SACL-STR).
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PMID:Low vagal activity as mediating mechanism for the relationship between personality factors and gastric symptoms in functional dyspepsia. 808 63

Patients with symptoms of GERD and dyspepsia are among the most common consulters in general practice and are different from their counterparts in the community who choose not to consult although they suffer from similar symptoms. They represent a heterogeneous group with considerable symptom overlap. They have a relatively poor quality of life and endoscopic findings can only explain symptoms in about half of these patients. Thus psychosocial factors which could contribute to their morbidity should be explored. While some studies have methodological shortcomings, main findings are that key psychological factors are anxiety, tension, neuroticism, somatization, fears of malignancy, negative assessment of health, depression, a poor social network and less effective coping strategies. Physical illness is likely to bring on psychological distress due to discomfort or threat of ill health. Cognizance of psychosocial factors will facilitate an understanding of the underlying problems and will improve diagnosis and selection of optimal treatment.
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PMID:Psychosocial factors and their role in symptomatic gastroesophageal reflux disease and functional dyspepsia. 889 45

Functional disorders like functional dyspepsia, irritable bowel syndrome and non-cardiac chest pain are common diseases. No organic lesion can be found to explain the often disabling symptoms. Typical features of functional dyspepsia are anxiety, depression, neuroticism, visceral hypersensitivity, abnormal autonomic nerve activity with a weak vagal and an higher sympathetic tone, and impairment of gastric accommodation. This last abnormality may be due to weak vagal tone and poor adaptive relaxation of the proximal stomach. The degree of dysfunction of the variables is sometimes correlated, suggesting that the pathogenetic factors may be interacting in a viscious circle. Medical therapy is often unsuccessful, but extensive research in the field has given better insight into the pathophysiological mechanisms, giving hope for new therapeutic modalities, including visceral analgesics. It may still be difficult, however, to distinguish organic from functional disorders. Reliable tests of visceral hypersensitivity would be helpful in this respect.
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PMID:[When you get a gut feeling...]. 901 85


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